Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Extirpate

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Choose target card in a graveyard other than a basic land card. Search its owner's graveyard, hand, and library for all cards with the same name as that card and exile them. Then that player shuffles.

Go Blank

Target player discards two cards. Then exile that player's graveyard.

Raven's Crime

Target player discards a card.
Retrace (You may cast this card from your graveyard by discarding a land card in addition to paying its other costs.)

Hopeless Nightmare

When Hopeless Nightmare enters, each opponent discards a card and loses 2 life.
When Hopeless Nightmare is put into a graveyard from the battlefield, scry 2.
{2}{B}: Sacrifice Hopeless Nightmare.

Davriel's Shadowfugue

Target player discards two cards and loses 2 life.

Horrifying Revelation

Target player discards a card, then mills a card.

Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Hymn to Tourach

Target player discards two cards at random.

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Cloak of Confusion

Enchant creature you control
Whenever enchanted creature attacks and isn't blocked, you may have it assign no combat damage this turn. If you do, defending player discards a card at random.

Lightning Skelemental

Trample, haste
Whenever Lightning Skelemental deals combat damage to a player, that player discards two cards.
At the beginning of the end step, sacrifice Lightning Skelemental.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Mind Peel

Buyback {2}{B}{B} (You may pay an additional {2}{B}{B} as you cast this spell. If you do, put this card into your hand as it resolves.)
Target player discards a card.

Death Cloud

Each player loses X life, discards X cards, sacrifices X creatures of their choice, then sacrifices X lands of their choice.

Cabal Shrine

Whenever a player casts a spell, that player discards X cards, where X is the number of cards in all graveyards with the same name as that spell.

Tendrils of Despair

As an additional cost to cast this spell, sacrifice a creature.
Target opponent discards two cards.

Deception

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Black Lotus

{T}, Sacrifice Black Lotus: Add three mana of any one color.

Gnat Miser

Each opponent's maximum hand size is reduced by one.

Demogorgon's Clutches

Target opponent discards two cards, mills two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Funeral Charm

Choose one —
• Target player discards a card.
• Target creature gets +2/-1 until end of turn.
• Target creature gains swampwalk until end of turn. (It can't be blocked as long as defending player controls a Swamp.)

Mox Jet

Mind Twist

Target player discards X cards at random.

Kroxa, Titan of Death's Hunger

When Kroxa enters, sacrifice it unless it escaped.
Whenever Kroxa enters or attacks, each opponent discards a card, then each opponent who didn't discard a nonland card this way loses 3 life.
Escape—{B}{B}{R}{R}, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Distress

Target player reveals their hand. You choose a nonland card from it. That player discards that card.

Dream Salvage

Draw cards equal to the number of cards target opponent discarded this turn.

Dire Undercurrents

Whenever a blue creature you control enters, you may have target player draw a card.
Whenever a black creature you control enters, you may have target player discard a card.

Swamp

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Coercion

Target opponent reveals their hand. You choose a card from it. That player discards that card.

Delirium Skeins

Hypnotic Specter

Flying
Whenever Hypnotic Specter deals damage to an opponent, that player discards a card at random.

Cabal Interrogator

{X}{B}, {T}: Target player reveals X cards from their hand and you choose one of them. That player discards that card. Activate only as a sorcery.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Elderfang Disciple

When Elderfang Disciple enters, each opponent discards a card.

Blackmail

Target player reveals three cards from their hand and you choose one of them. That player discards that card.

Pilfer

Target opponent reveals their hand. You choose a nonland card from it. That player discards that card.

Encroach

Target player reveals their hand. You choose a nonbasic land card from it. That player discards that card.

Heartless Pillage

Target opponent discards two cards.
Raid — If you attacked this turn, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Drill Bit

Spectacle {B} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Target player reveals their hand. You choose a nonland card from it. That player discards that card.

Cabal Slaver

Whenever a Goblin deals combat damage to a player, that player discards a card.

Chain of Smog

Target player discards two cards. That player may copy this spell and may choose a new target for that copy.

Lay Bare the Heart

Target opponent reveals their hand. You choose a nonlegendary, nonland card from it. That player discards that card.

Mardu Skullhunter

Mardu Skullhunter enters tapped.
Raid — When Mardu Skullhunter enters, if you attacked this turn, target opponent discards a card.

Bog Down

Kicker—Sacrifice two lands. (You may sacrifice two lands in addition to any other costs as you cast this spell.)
Target player discards two cards. If this spell was kicked, that player discards three cards instead.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Burglar Rat

When this creature enters, each opponent discards a card.

Dark Inquiry

Shattered Dreams

Target opponent reveals their hand. You choose an artifact card from it. That player discards that card.

Memory Leak

Target opponent reveals their hand. You choose a nonland card from that player's graveyard or hand and exile it.
Cycling {1} ({1}, Discard this card: Draw a card.)

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Diplomacy of the Wastes

Target opponent reveals their hand. You choose a nonland card from it. That player discards that card. If you control a Warrior, that player loses 2 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Scroll Rack

{1}, {T}: Exile any number of cards from your hand face down. Put that many cards from the top of your library into your hand. Then look at the exiled cards and put them on top of your library in any order.

Wrench Mind

Target player discards two cards unless they discard an artifact card.

Inquisition of Kozilek

Target player reveals their hand. You choose a nonland card from it with mana value 3 or less. That player discards that card.

Blightning

Blightning deals 3 damage to target player or planeswalker. That player or that planeswalker's controller discards two cards.

Memory Theft

Target opponent reveals their hand. You choose a nonland card from it. That player discards that card. You may put a card that has an Adventure that player owns from exile into that player's graveyard.

Ostracize

Target opponent reveals their hand. You choose a creature card from it. That player discards that card.

Specter's Wail

Mire's Toll

Target player reveals a number of cards from their hand equal to the number of Swamps you control. You choose one of them. That player discards that card.

Mental Agony

The Rack

As The Rack enters, choose an opponent.
At the beginning of the chosen player's upkeep, The Rack deals X damage to that player, where X is 3 minus the number of cards in their hand.

Down for Repairs

Target opponent reveals their hand. You choose a nonland card from it. That player discards that card. Destroy up to one target Attraction that player controls. (It's put into their junkyard.)

Cabal Therapy

Choose a nonland card name. Target player reveals their hand and discards all cards with that name.
Flashback—Sacrifice a creature. (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Skullscorch

Target player discards two cards at random unless that player has Skullscorch deal 4 damage to them.

Stabwhisker the Odious

At the beginning of each opponent's upkeep, that player loses 1 life for each card fewer than three in their hand.

Nezumi Shortfang

{1}{B}, {T}: Target opponent discards a card. Then if that player has no cards in hand, flip Nezumi Shortfang.

Nezumi Shortfang // Stabwhisker the Odious

Surgical Extraction

({B/P} can be paid with either {B} or 2 life.)
Choose target card in a graveyard other than a basic land card. Search its owner's graveyard, hand, and library for any number of cards with the same name as that card and exile them. Then that player shuffles.

Divest

Target player reveals their hand. You choose an artifact or creature card from it. That player discards that card.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Honden of Night's Reach

At the beginning of your upkeep, target opponent discards a card for each Shrine you control.

Mind Drain

Target opponent discards two cards, mills a card, and loses 1 life. You gain 1 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Gamble

Search your library for a card, put that card into your hand, discard a card at random, then shuffle.

Scepter of Fugue

{1}{B}, {T}: Target player discards a card. Activate only during your turn.

Chilling Apparition

{B}: Regenerate Chilling Apparition.
Whenever Chilling Apparition deals combat damage to a player, that player discards a card.

Hollow Specter

Flying
Whenever Hollow Specter deals combat damage to a player, you may pay {X}. If you do, that player reveals X cards from their hand and you choose one of them. That player discards that card.

Devour Intellect

Target opponent discards a card. If mana from a Treasure was spent to cast this spell, instead that player reveals their hand, you choose a nonland card from it, then that player discards that card.