Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Swamp

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.