Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Celestine, the Living Saint

Flying, lifelink
Healing Tears — At the beginning of your end step, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Shattered Angel

Flying
Whenever a land an opponent controls enters, you may gain 3 life.

Vampire Nighthawk

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Markov Purifier

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay {2}. If you do, draw a card.

Valkyrie Harbinger

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of each end step, if you gained 4 or more life this turn, create a 4/4 white Angel creature token with flying and vigilance.

Thran Dynamo

Mangara, the Diplomat

Lifelink
Whenever an opponent attacks with creatures, if two or more of those creatures are attacking you and/or planeswalkers you control, draw a card.
Whenever an opponent casts their second spell each turn, draw a card.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Liesa, Forgotten Archangel

Flying, lifelink
Whenever another nontoken creature you control dies, return that card to its owner's hand at the beginning of the next end step.
If a creature an opponent controls would die, exile it instead.

Pristine Talisman

Resplendent Angel

Flying
At the beginning of each end step, if you gained 5 or more life this turn, create a 4/4 white Angel creature token with flying and vigilance.
{3}{W}{W}{W}: Until end of turn, Resplendent Angel gets +2/+2 and gains lifelink.

Monologue Tax

Whenever an opponent casts their second spell each turn, you create a Treasure token.

Boon Reflection

If you would gain life, you gain twice that much life instead.

Kaya's Guile

Choose two —
• Each opponent sacrifices a creature of their choice.
• Exile all opponents' graveyards.
• Create a 1/1 white and black Spirit creature token with flying.
• You gain 4 life.
Entwine {3} (Choose all if you pay the entwine cost.)

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Plains

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature of their choice and you return up to one target creature card from your graveyard to your hand.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Leaden Myr

Kaya's Ghostform

Enchant creature or planeswalker you control
When enchanted permanent dies or is put into exile, return that card to the battlefield under your control.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Baleful Mastery

You may pay {1}{B} rather than pay this spell's mana cost.
If the {1}{B} cost was paid, an opponent draws a card.
Exile target creature or planeswalker.

Gold Myr

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Shineshadow Snarl

As Shineshadow Snarl enters, you may reveal a Plains or Swamp card from your hand. If you don't, Shineshadow Snarl enters tapped.
{T}: Add {W} or {B}.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Gilded Lotus

Kunoros, Hound of Athreos

Vigilance, menace, lifelink
Creature cards in graveyards can't enter the battlefield.
Players can't cast spells from graveyards.

Dawn of Hope

Whenever you gain life, you may pay {2}. If you do, draw a card.
{3}{W}: Create a 1/1 white Soldier creature token with lifelink.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Liesa, Shroud of Dusk

Rather than pay {2} for each previous time you've cast this spell from the command zone this game, pay 2 life that many times.
Flying, lifelink
Whenever a player casts a spell, they lose 2 life.

Orzhov Signet

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Blackblade Reforged

Equipped creature gets +1/+1 for each land you control.
Equip legendary creature {3}
Equip {7}

Not Dead After All

Until end of turn, target creature you control gains "When this creature dies, return it to the battlefield tapped under its owner's control, then create a Wicked Role token attached to it." (Enchanted creature gets +1/+1. When this Aura is put into a graveyard, each opponent loses 1 life.)

Dark Ritual

Consuming Sepulcher

At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Tithing Blade

When Tithing Blade enters, each opponent sacrifices a creature of their choice.
Craft with creature {4}{B} ({4}{B}, Exile this artifact, Exile a creature you control or a creature card from your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Tithing Blade // Consuming Sepulcher

Night's Whisper

Grimclimb Pathway

Brightclimb Pathway

Brightclimb Pathway // Grimclimb Pathway

Swamp

True Conviction

Creatures you control have double strike and lifelink.

Sunscorch Regent

Flying
Whenever an opponent casts a spell, put a +1/+1 counter on Sunscorch Regent and you gain 1 life.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Sol Ring

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Blade of Selves

Equipped creature has myriad. (Whenever it attacks, for each opponent other than defending player, you may create a token copy that's tapped and attacking that player or a planeswalker they control. Exile the tokens at end of combat.)
Equip {4}

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

The Book of Exalted Deeds

At the beginning of your end step, if you gained 3 or more life this turn, create a 3/3 white Angel creature token with flying.
{W}{W}{W}, {T}, Exile The Book of Exalted Deeds: Put an enlightened counter on target Angel. It gains "You can't lose the game and your opponents can't win the game." Activate only as a sorcery.

Sephara, Sky's Blade

You may pay {W} and tap four untapped creatures you control with flying rather than pay this spell's mana cost.
Flying, lifelink
Other creatures you control with flying have indestructible. (Damage and effects that say "destroy" don't destroy them.)

Loran's Escape

Target artifact or creature gains hexproof and indestructible until end of turn. Scry 1.

Ancient Craving

You draw three cards and you lose 3 life.

Soul Warden

Whenever another creature enters, you gain 1 life.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Command Tower

Clackbridge Troll

Trample, haste
When Clackbridge Troll enters, target opponent creates three 0/1 white Goat creature tokens.
At the beginning of combat on your turn, any opponent may sacrifice a creature of their choice. If a player does, tap Clackbridge Troll, you gain 3 life, and you draw a card.

Fellwar Stone

Baneslayer Angel

Flying, first strike, lifelink, protection from Demons and from Dragons

Fetid Heath

{T}: Add {C}.
{W/B}, {T}: Add {W}{W}, {W}{B}, or {B}{B}.

Ambition's Cost

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Nykthos Paragon

Whenever you gain life, you may put that many +1/+1 counters on each creature you control. Do this only once each turn.

Sign in Blood

Target player draws two cards and loses 2 life.

Lyra Dawnbringer

Flying, first strike, lifelink
Other Angels you control get +1/+1 and have lifelink.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.