Eternal Isolation

Put target creature with power 4 or greater on the bottom of its owner's library.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Garza Zol, Plague Queen

Flying, haste
Whenever a creature dealt damage by Garza Zol, Plague Queen this turn dies, put a +1/+1 counter on Garza Zol.
Whenever Garza Zol deals combat damage to a player, you may draw a card.

Plague Spitter

At the beginning of your upkeep, Plague Spitter deals 1 damage to each creature and each player.
When Plague Spitter dies, it deals 1 damage to each creature and each player.

Sick and Tired

Two target creatures each get -1/-1 until end of turn.

Festering Wound

Enchant creature
At the beginning of your upkeep, you may put an infection counter on Festering Wound.
At the beginning of the upkeep of enchanted creature's controller, Festering Wound deals X damage to that player, where X is the number of infection counters on Festering Wound.

Blight Sickle

Equipped creature gets +1/+0 and has wither. (It deals damage to creatures in the form of -1/-1 counters.)
Equip {2}

Illness in the Ranks

Fevered Convulsions

{2}{B}{B}: Put a -1/-1 counter on target creature.

Toxic Nim

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Regenerate Toxic Nim.

Oversold Cemetery

At the beginning of your upkeep, if you have four or more creature cards in your graveyard, you may return target creature card from your graveyard to your hand.

Mountain

Plague Engineer

Deathtouch
As Plague Engineer enters, choose a creature type.
Creatures of the chosen type your opponents control get -1/-1.

Void Beckoner

Deathtouch
Cycling {2}{B} ({2}{B}, Discard this card: Draw a card.)
When you cycle Void Beckoner, put a deathtouch counter on target creature you control.

Isolation Zone

When Isolation Zone enters, exile target creature or enchantment an opponent controls until Isolation Zone leaves the battlefield. (That permanent returns under its owner's control.)

Tainted Peak

{T}: Add {C}.
{T}: Add {B} or {R}. Activate only if you control a Swamp.

Toxin Sliver

Whenever a Sliver deals combat damage to a creature, destroy that creature. It can't be regenerated.

Sickening Shoal

You may exile a black card with mana value X from your hand rather than pay this spell's mana cost.
Target creature gets -X/-X until end of turn.

Infectious Bloodlust

Enchant creature
Enchanted creature gets +2/+1, has haste, and attacks each combat if able.
When enchanted creature dies, you may search your library for a card named Infectious Bloodlust, reveal it, put it into your hand, then shuffle.

Plaguecrafter

When Plaguecrafter enters, each player sacrifices a creature or planeswalker of their choice. Each player who can't discards a card.

Plague Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{T}: Add {C}.

Blighted Woodland

{T}: Add {C}.
{3}{G}, {T}, Sacrifice Blighted Woodland: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Viral Drake

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{3}{U}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Virulent Sliver

All Sliver creatures have poisonous 1. (Whenever a Sliver deals combat damage to a player, that player gets a poison counter. A player with ten or more poison counters loses the game.)

Infectious Rage

Enchant creature
Enchanted creature gets +2/-1.
When enchanted creature dies, choose a creature at random Infectious Rage can enchant. Return Infectious Rage to the battlefield attached to that creature.

Quag Sickness

Enchant creature
Enchanted creature gets -1/-1 for each Swamp you control.

Virulent Plague

Isolate

Exile target permanent with mana value 1.

Necrotic Plague

Enchant creature
Enchanted creature has "At the beginning of your upkeep, sacrifice this creature."
When enchanted creature dies, its controller chooses target creature one of their opponents controls. Return Necrotic Plague from its owner's graveyard to the battlefield attached to that creature.

Island

Plague Belcher

Menace
When Plague Belcher enters, put two -1/-1 counters on target creature you control.
Whenever another Zombie you control dies, each opponent loses 1 life.

Tainted Isle

{T}: Add {C}.
{T}: Add {U} or {B}. Activate only if you control a Swamp.

Contagion

You may pay 1 life and exile a black card from your hand rather than pay this spell's mana cost.
Distribute two -2/-1 counters among one or two target creatures.

Forest

Nausea

All creatures get -1/-1 until end of turn.

Tainted Field

{T}: Add {C}.
{T}: Add {W} or {B}. Activate only if you control a Swamp.

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Dust Corona

Enchant creature
Enchanted creature gets +2/+0 and can't be blocked by creatures with flying.

Incremental Blight

Put a -1/-1 counter on target creature, two -1/-1 counters on another target creature, and three -1/-1 counters on a third target creature.

Blightwidow

Reach (This creature can block creatures with flying.)
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Sicken

Enchant creature
Enchanted creature gets -1/-1.
Cycling {2} ({2}, Discard this card: Draw a card.)

Blighted Agent

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Blighted Agent can't be blocked.

Plague Boiler

At the beginning of your upkeep, put a plague counter on Plague Boiler.
{1}{B}{G}: Put a plague counter on Plague Boiler or remove a plague counter from it.
When Plague Boiler has three or more plague counters on it, sacrifice it. If you do, destroy all nonland permanents.

Skithiryx, the Blight Dragon

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx, the Blight Dragon gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

Diseased Vermin

Whenever Diseased Vermin deals combat damage to a player, put an infection counter on it.
At the beginning of your upkeep, Diseased Vermin deals X damage to target opponent previously dealt damage by it, where X is the number of infection counters on it.

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Suffering

Pain

Pain // Suffering

Karona, False God

Haste
At the beginning of each player's upkeep, that player untaps Karona, False God and gains control of it.
Whenever Karona attacks, creatures of the creature type of your choice get +3/+3 until end of turn.

Plains

Desecration Plague

Blowfly Infestation

Whenever a creature dies, if it had a -1/-1 counter on it, put a -1/-1 counter on target creature.

Virulent Wound

Put a -1/-1 counter on target creature. When that creature dies this turn, its controller gets a poison counter.

Fevered Visions

At the beginning of each player's end step, that player draws a card. If the player is your opponent and has four or more cards in hand, Fevered Visions deals 2 damage to that player.

Spread the Sickness

Destroy target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Plague Stinger

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Plague Wind

Destroy all creatures you don't control. They can't be regenerated.

Quarantine Field

Quarantine Field enters with X isolation counters on it.
When Quarantine Field enters, for each isolation counter on it, exile up to one target nonland permanent an opponent controls until Quarantine Field leaves the battlefield.

Each player loses a third of their life, then discards a third of the cards in their hand, then sacrifices a third of the creatures they control of their choice, then sacrifices a third of the lands they control of their choice. Round up each time.

Engineered Plague

As Engineered Plague enters, choose a creature type.
All creatures of the chosen type get -1/-1.

Temple of Malady

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {B} or {G}.

Karona's Zealot

Morph {3}{W}{W} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)
When Karona's Zealot is turned face up, all damage that would be dealt to it this turn is dealt to target creature instead.

Blight Mamba

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{1}{G}: Regenerate Blight Mamba.

Swamp

Spreading Plague

Whenever a creature enters, destroy all other creatures that share a color with it. They can't be regenerated.

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Traveling Plague

Enchant creature
At the beginning of each upkeep, put a plague counter on Traveling Plague.
Enchanted creature gets -1/-1 for each plague counter on Traveling Plague.
When enchanted creature leaves the battlefield, that creature's controller returns Traveling Plague from its owner's graveyard to the battlefield.

Infectious Horror

Whenever Infectious Horror attacks, each opponent loses 2 life.

Virulent Swipe

Target creature gets +2/+0 and gains deathtouch until end of turn.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)

Instill Infection

Put a -1/-1 counter on target creature.
Draw a card.

Tainted Wood

{T}: Add {C}.
{T}: Add {B} or {G}. Activate only if you control a Swamp.

Contagious Nim

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)