Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Chittering Rats

When Chittering Rats enters, target opponent puts a card from their hand on top of their library.

Spider

Lolth, Spider Queen Emblem

Whenever an opponent is dealt combat damage by one or more creatures you control, if that player lost less than 8 life this turn, they lose life equal to the difference.

Gixian Puppeteer

Whenever you draw your second card each turn, each opponent loses 2 life and you gain 2 life.
When Gixian Puppeteer dies, return another target creature card with mana value 3 or less from your graveyard to the battlefield.

Insatiable Avarice

Spree (Choose one or more additional costs.)
+ {2} — Search your library for a card, then shuffle and put that card on top.
+ {B}{B} — Target player draws three cards and loses 3 life.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Myr Convert

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
{T}, Pay 2 life: Add one mana of any color.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Feed the Infection

You draw three cards and you lose 3 life.
Corrupted — Each opponent who has three or more poison counters loses 3 life.

Sheoldred's Headcleaver

Menace
Toxic 2 (Players dealt combat damage by this creature also get two poison counters.)

Bonepicker Skirge

Flying
Corrupted — As long as an opponent has three or more poison counters, Bonepicker Skirge has deathtouch and lifelink.

Offer Immortality

Target creature gains deathtouch and indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Howling Mine

At the beginning of each player's draw step, if Howling Mine is untapped, that player draws an additional card.

Mikokoro, Center of the Sea

{T}: Add {C}.
{2}, {T}: Each player draws a card.

Commander's Plate

Equipped creature gets +3/+3 and has protection from each color that's not in your commander's color identity.
Equip commander {3}
Equip {5}

Pestilent Syphoner

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Zenith Chronicler

Whenever a player casts their first multicolored spell each turn, each other player draws a card.

Caress of Phyrexia

Target player draws three cards, loses 3 life, and gets three poison counters.

Phyrexian Rager

When Phyrexian Rager enters, you draw a card and you lose 1 life.

Plague Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{T}: Add {C}.

Whisper of the Dross

Target creature gets -1/-1 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Cruel Grimnarch

Deathtouch
When Cruel Grimnarch enters, each opponent discards a card. For each opponent who can't, you gain 4 life.

Dross Skullbomb

{1}, Sacrifice Dross Skullbomb: Draw a card.
{2}{B}, Sacrifice Dross Skullbomb: Return target creature card from your graveyard to your hand. Draw a card. Activate only as a sorcery.

Doom Blade

Drown in Ichor

Target creature gets -4/-4 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Vraan, Executioner Thane

Whenever one or more other creatures you control die, each opponent loses 2 life and you gain 2 life. This ability triggers only once each turn.

Reaper of Sheoldred

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever a source deals damage to Reaper of Sheoldred, that source's controller gets a poison counter.

Core Prowler

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Core Prowler dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Phyrexian Gargantua

When Phyrexian Gargantua enters, you draw two cards and you lose 2 life.

Jet Medallion

Black spells you cast cost {1} less to cast.

Stinging Hivemaster

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Stinging Hivemaster dies, create a 1/1 colorless Phyrexian Mite artifact creature token with toxic 1 and "This creature can't block."

Annihilating Glare

As an additional cost to cast this spell, pay {4} or sacrifice an artifact or creature.
Destroy target creature or planeswalker.

Virulent Wound

Put a -1/-1 counter on target creature. When that creature dies this turn, its controller gets a poison counter.

Phyrexian Mite

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
This creature can't block.

Geth's Verdict

Target player sacrifices a creature of their choice and loses 1 life.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

The Seedcore

{T}: Add {C}.
{T}: Add one mana of any color. Spend this mana only to cast Phyrexian creature spells.
Corrupted — {T}: Target 1/1 creature gets +2/+1 until end of turn. Activate only if an opponent has three or more poison counters.

Gulping Scraptrap

When Gulping Scraptrap enters or dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Scheming Aspirant

Whenever you proliferate, each opponent loses 2 life and you gain 2 life.

Dread Presence

Whenever a Swamp you control enters, choose one —
• You draw a card and you lose 1 life.
• Dread Presence deals 2 damage to any target and you gain 2 life.

Font of Mythos

At the beginning of each player's draw step, that player draws two additional cards.

Sign in Blood

Target player draws two cards and loses 2 life.

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Swamp

Dread Return

Return target creature card from your graveyard to the battlefield.
Flashback—Sacrifice three creatures. (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Argentum Masticore

First strike, protection from multicolored
At the beginning of your upkeep, sacrifice Argentum Masticore unless you discard a card. When you discard a card this way, destroy target nonland permanent an opponent controls with mana value less than or equal to the mana value of the discarded card.

Bilious Skulldweller

Deathtouch
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Vat of Rebirth

Whenever another artifact or creature you control is put into a graveyard from the battlefield, put an oil counter on Vat of Rebirth.
{2}{B}, {T}, Remove four oil counters from Vat of Rebirth: Return target creature card from your graveyard to the battlefield. Activate only as a sorcery.

Lolth, Spider Queen

Whenever a creature you control dies, put a loyalty counter on Lolth, Spider Queen.
0: You draw a card and you lose 1 life.
−3: Create two 2/1 black Spider creature tokens with menace and reach.
−8: You get an emblem with "Whenever an opponent is dealt combat damage by one or more creatures you control, if that player lost less than 8 life this turn, they lose life equal to the difference."

Temple Bell

Ravenous Necrotitan

Corrupted — When Ravenous Necrotitan enters, sacrifice a creature unless an opponent has three or more poison counters.

Cut Down

Destroy target creature with total power and toughness 5 or less.

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Hand of the Praetors

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Other creatures you control with infect get +1/+1.
Whenever you cast a creature spell with infect, target player gets a poison counter.

The Dross Pits

The Dross Pits enters tapped.
{T}: Add {B}.
{1}{B}, {T}, Sacrifice The Dross Pits: Draw a card.

Dune Mover

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Dune Mover enters, you may search your library for a basic land card, reveal it, then shuffle and put that card on top.

Phyrexian Atlas

{T}: Add one mana of any color.
Corrupted — Whenever Phyrexian Atlas becomes tapped, each opponent who has three or more poison counters loses 1 life.

Scrawling Crawler

At the beginning of your upkeep, each player draws a card.
Whenever an opponent draws a card, that player loses 1 life.

Vat Emergence

Put target creature card from a graveyard onto the battlefield under your control. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Battle-Rage Blessing

Phyresis Outbreak

Each opponent gets a poison counter. Then each creature your opponents control gets -1/-1 until end of turn for each poison counter its controller has.

Necrosquito

Flying
Necrosquito enters with two oil counters on it.
Necrosquito gets +1/+1 for each oil counter on it.
Whenever another creature or artifact you control is put into a graveyard from the battlefield, put an oil counter on Necrosquito.

Necrogen Communion

Enchant creature you control
Enchanted creature has toxic 2. (Players dealt combat damage by it also get two poison counters.)
When enchanted creature dies, return that card to the battlefield under your control.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Darksteel Plate

Indestructible
Equipped creature has indestructible.
Equip {2}

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Monumental Corruption

Target player draws X cards and loses X life, where X is the number of artifacts you control.

Phyresis

Enchant creature
Enchanted creature has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Chittering Skitterling

Corrupted — Sacrifice an artifact or creature: Draw a card. Activate only if an opponent has three or more poison counters and only once each turn.

The True Scriptures

(As this Saga enters and after your draw step, add a lore counter.)
I — For each opponent, destroy up to one target creature or planeswalker that player controls.
II — Each opponent discards three cards, then mills three cards.
III — Put all creature cards from all graveyards onto the battlefield under your control. Exile The True Scriptures, then return it to the battlefield (front face up).

Sheoldred

Menace
When Sheoldred enters, each opponent sacrifices a nontoken creature or planeswalker of their choice.
{4}{B}: Exile Sheoldred, then return it to the battlefield transformed under its owner's control. Activate only as a sorcery and only if an opponent has eight or more cards in their graveyard.

Sheoldred // The True Scriptures

Blightbelly Rat

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Blightbelly Rat dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Prosthetic Injector

Equipped creature gets +0/+2 and has toxic 1. (Players dealt combat damage by equipped creature also get a poison counter.)
Equip {1}