Mindwrack Demon

Flying, trample
When Mindwrack Demon enters the battlefield, mill four cards.
Delirium — At the beginning of your upkeep, you lose 4 life unless there are four or more card types among cards in your graveyard.

Phyrexian Soulgorger

Cumulative upkeep—Sacrifice a creature. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Go for the Throat

Master of the Feast

Flying
At the beginning of your upkeep, each opponent draws a card.

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Rust Elemental

Flying
At the beginning of your upkeep, sacrifice an artifact other than Rust Elemental. If you can't, tap Rust Elemental and you lose 4 life.

Evacuation

Return all creatures to their owners' hands.

Infernal Grasp

Destroy target creature. You lose 2 life.

Thought Nibbler

Flying
Your maximum hand size is reduced by two.

Negate

Drinker of Sorrow

Drinker of Sorrow can't block.
Whenever Drinker of Sorrow deals combat damage, sacrifice a permanent.

Thought Eater

Flying
Your maximum hand size is reduced by three.

Lord Skitter, Sewer King

Whenever another Rat enters the battlefield under your control, exile up to one target card from an opponent's graveyard.
At the beginning of combat on your turn, create a 1/1 black Rat creature token with "This creature can't block."

Dimir Signet

Sudden Substitution

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Exchange control of target noncreature spell and target creature. Then the spell's controller may choose new targets for it.

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Moroii

Flying
At the beginning of your upkeep, you lose 1 life.

Thought Devourer

Flying
Your maximum hand size is reduced by four.

Whispersilk Cloak

Equipped creature can't be blocked and has shroud. (It can't be the target of spells or abilities.)
Equip {2}

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Jon Irenicus, Shattered One

At the beginning of your end step, target opponent gains control of up to one target creature you control. Put two +1/+1 counters on it and tap it. It's goaded for the rest of the game and it gains "This creature can't be sacrificed." (It attacks each combat if able and attacks a player other than you if able.)
Whenever a creature you own but don't control attacks, you draw a card.

Evil Eye of Urborg

Non-Eye creatures you control can't attack.
Whenever Evil Eye of Urborg becomes blocked by a creature, destroy that creature.

Gilded Drake

Flying
When Gilded Drake enters the battlefield, exchange control of Gilded Drake and up to one target creature an opponent controls. If you don't or can't make an exchange, sacrifice Gilded Drake. This ability still resolves if its target becomes illegal.

Ebon Drake

Flying
Whenever a player casts a spell, you lose 1 life.

Blighted Agent

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Blighted Agent can't be blocked.

Archfiend of the Dross

Flying
Archfiend of the Dross enters the battlefield with four oil counters on it.
At the beginning of your upkeep, remove an oil counter from Archfiend of the Dross. Then if it has no oil counters on it, you lose the game.
Whenever a creature an opponent controls dies, its controller loses 2 life.

Asmodeus the Archfiend

Binding Contract — If you would draw a card, exile the top card of your library face down instead.
{B}{B}{B}: Draw seven cards.
{B}: Return all cards exiled with Asmodeus the Archfiend to their owner's hand and you lose that much life.

Changeling Outcast

Changeling (This card is every creature type.)
Changeling Outcast can't block and can't be blocked.

Pongify

Destroy target creature. It can't be regenerated. Its controller creates a 3/3 green Ape creature token.

Grid Monitor

Tormented Soul

Tormented Soul can't block and can't be blocked.

Disdainful Stroke

Counter target spell with mana value 4 or greater.

Dissipation Field

Whenever a permanent deals damage to you, return it to its owner's hand.

Dimir Locket

{T}: Add {U} or {B}.
{U/B}{U/B}{U/B}{U/B}, {T}, Sacrifice Dimir Locket: Draw two cards.

Grinning Demon

At the beginning of your upkeep, you lose 2 life.
Morph {2}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Steel Golem

Minamo Scrollkeeper

Defender
Your maximum hand size is increased by one.

Rotting Regisaur

At the beginning of your upkeep, discard a card.

Marang River Prowler

Marang River Prowler can't block and can't be blocked.
You may cast Marang River Prowler from your graveyard as long as you control a black or green permanent.

Slither Blade

Counterspell

Crawlspace

No more than two creatures can attack you each combat.

Asinine Antics

You may cast Asinine Antics as though it had flash if you pay {2} more to cast it.
For each creature your opponents control, create a Cursed Role token attached to that creature. (If you control another Role on it, put that one into the graveyard. Enchanted creature is 1/1.)

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this artifact: Add one mana of any color.")

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Witch-king of Angmar

Flying
Whenever one or more creatures deal combat damage to you, each opponent sacrifices a creature that dealt combat damage to you this turn. The Ring tempts you.
Discard a card: Witch-king of Angmar gains indestructible until end of turn. Tap it.

Fretwork Colony

Fretwork Colony can't block.
At the beginning of your upkeep, put a +1/+1 counter on Fretwork Colony and you lose 1 life.

Wretched Anurid

Whenever another creature enters the battlefield, you lose 1 life.

Abyssal Persecutor

Flying, trample
You can't win the game and your opponents can't lose the game.

Essence Scatter

Phyrexian Vatmother

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
At the beginning of your upkeep, you get a poison counter.

Heartless Summoning

Creature spells you cast cost {2} less to cast.
Creatures you control get -1/-1.

Sygg, River Cutthroat

At the beginning of each end step, if an opponent lost 3 or more life this turn, you may draw a card. (Damage causes loss of life.)

Demonic Taskmaster

Flying
At the beginning of your upkeep, sacrifice a creature other than Demonic Taskmaster.

Filthy Cur

Whenever Filthy Cur is dealt damage, you lose that much life.

Alexi's Cloak

Flash
Enchant creature
Enchanted creature has shroud. (It can't be the target of spells or abilities.)

Gisa, Glorious Resurrector

If a creature an opponent controls would die, exile it instead.
At the beginning of your upkeep, put all creature cards exiled with Gisa, Glorious Resurrector onto the battlefield under your control. They gain decayed. (A creature with decayed can't block. When it attacks, sacrifice it at end of combat.)

Vislor Turlough

Deal with the Black Guardian — When Vislor Turlough enters the battlefield, you may have an opponent gain control of it. If you do, it's goaded for as long as they control it.
At the beginning of your end step, draw a card, then you lose life equal to the number of cards in your hand.
Doctor's companion (You can have two commanders if the other is the Doctor.)

Pitiless Horde

At the beginning of your upkeep, you lose 2 life.
Dash {2}{B}{B} (You may cast this spell for its dash cost. If you do, it gains haste, and it's returned from the battlefield to its owner's hand at the beginning of the next end step.)