Cut Your Losses

Casualty 2 (As you cast this spell, you may sacrifice a creature with power 2 or greater. When you do, copy this spell and you may choose a new target for the copy.)
Target player mills half their library, rounded down.

Underground River

{T}: Add {C}.
{T}: Add {U} or {B}. Underground River deals 1 damage to you.

Darkslick Shores

Darkslick Shores enters tapped unless you control two or fewer other lands.
{T}: Add {U} or {B}.

Rapid Hybridization

Destroy target creature. It can't be regenerated. That creature's controller creates a 3/3 green Frog Lizard creature token.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Jace, Wielder of Mysteries

If you would draw a card while your library has no cards in it, you win the game instead.
+1: Target player mills two cards. Draw a card.
−8: Draw seven cards. Then if your library has no cards in it, you win the game.

Traumatize

Target player mills half their library, rounded down.

Dramatic Reversal

Untap all nonland permanents you control.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard Takenuma, Abandoned Mire: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.

Crashing Drawbridge

Defender
{T}: Creatures you control gain haste until end of turn.

Fractured Sanity

Each opponent mills fourteen cards.
Cycling {1}{U} ({1}{U}, Discard this card: Draw a card.)
When you cycle Fractured Sanity, each opponent mills four cards.

Mesmeric Orb

Whenever a permanent becomes untapped, that permanent's controller mills a card.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Dauthi Voidwalker

Shadow (This creature can block or be blocked by only creatures with shadow.)
If a card would be put into an opponent's graveyard from anywhere, instead exile it with a void counter on it.
{T}, Sacrifice Dauthi Voidwalker: Choose an exiled card an opponent owns with a void counter on it. You may play it this turn without paying its mana cost.

Bruvac the Grandiloquent

If an opponent would mill one or more cards, they mill twice that many cards instead. (To mill a card, a player puts the top card of their library into their graveyard.)

Can't Wake Up

Target player mills four cards. (Then exile this card. You may cast the creature later from exile.)

Cruel Somnophage

Cruel Somnophage's power and toughness are each equal to the number of creature cards in all graveyards.

Cruel Somnophage // Can't Wake Up

Laboratory Maniac

If you would draw a card while your library has no cards in it, you win the game instead.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Vizier of Tumbling Sands

{T}: Untap another target permanent.
Cycling {1}{U} ({1}{U}, Discard this card: Draw a card.)
When you cycle Vizier of Tumbling Sands, untap target permanent.

Takenuma

Whenever a creature leaves the battlefield, its controller draws a card.
Whenever chaos ensues, return target creature you control to its owner's hand.

Intruder Alarm

Creatures don't untap during their controllers' untap steps.
Whenever a creature enters, untap all creatures.

Hover Barrier

Dimir Aqueduct

Dimir Aqueduct enters tapped.
When Dimir Aqueduct enters, return a land you control to its owner's hand.
{T}: Add {U}{B}.

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this token: Add one mana of any color.")

Resculpt

Exile target artifact or creature. Its controller creates a 4/4 blue and red Elemental creature token.

Basalt Monolith

Basalt Monolith doesn't untap during your untap step.
{T}: Add {C}{C}{C}.
{3}: Untap Basalt Monolith.

Silent Arbiter

No more than one creature can attack each combat.
No more than one creature can block each combat.

Dimir Signet

King Macar, the Gold-Cursed

Inspired — Whenever King Macar, the Gold-Cursed becomes untapped, you may exile target creature. If you do, create a Gold token. (It's an artifact with "Sacrifice this artifact: Add one mana of any color.")

Undead Alchemist

If a Zombie you control would deal combat damage to a player, instead that player mills that many cards.
Whenever a creature card is put into an opponent's graveyard from their library, exile that card and create a 2/2 black Zombie creature token.

Drift of Phantasms

Defender (This creature can't attack.)
Flying
Transmute {1}{U}{U} ({1}{U}{U}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Manic Scribe

When Manic Scribe enters, each opponent mills three cards.
Delirium — At the beginning of each opponent's upkeep, if there are four or more card types among cards in your graveyard, that player mills three cards.

Tasha's Hideous Laughter

Each opponent exiles cards from the top of their library until that player has exiled cards with total mana value 20 or more.

Muddle the Mixture

Counter target instant or sorcery spell.
Transmute {1}{U}{U} ({1}{U}{U}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Mortivore

Mortivore's power and toughness are each equal to the number of creature cards in all graveyards.
{B}: Regenerate Mortivore. (The next time this creature would be destroyed this turn, instead tap it, remove it from combat, and heal all damage on it.)

Shipwreck Marsh

Shipwreck Marsh enters tapped unless you control two or more other lands.
{T}: Add {U} or {B}.

Ponder

Look at the top three cards of your library, then put them back in any order. You may shuffle.
Draw a card.

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Windfall

Each player discards their hand, then draws cards equal to the greatest number of cards a player discarded this way.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Fleet Swallower

Whenever Fleet Swallower attacks, target player mills half their library, rounded up.

Freed from the Real

Enchant creature
{U}: Tap enchanted creature.
{U}: Untap enchanted creature.

Court of Cunning

When Court of Cunning enters, you become the monarch.
At the beginning of your upkeep, any number of target players each mill two cards. If you're the monarch, each of those players mills ten cards instead. (To mill a card, a player puts the top card of their library into their graveyard.)

Terisian Mindbreaker

Whenever Terisian Mindbreaker attacks, defending player mills half their library, rounded up.
Unearth {1}{U}{U}{U} ({1}{U}{U}{U}: Return this card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step or if it would leave the battlefield. Unearth only as a sorcery.)

Bonehoard

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +X/+X, where X is the number of creature cards in all graveyards.
Equip {2}

The Haunt of Hightower

Flying, lifelink
Whenever The Haunt of Hightower attacks, defending player discards a card.
Whenever a card is put into an opponent's graveyard from anywhere, put a +1/+1 counter on The Haunt of Hightower.

Fraying Sanity

Enchant player
At the beginning of each end step, enchanted player mills X cards, where X is the number of cards put into their graveyard from anywhere this turn.

Mind Grind

Each opponent reveals cards from the top of their library until they reveal X land cards, then puts all cards revealed this way into their graveyard. X can't be 0.

Ioreth of the Healing House

{T}: Untap another target permanent.
{T}: Untap two other target legendary creatures.

Ruin Crab

Landfall — Whenever a land you control enters, each opponent mills three cards. (To mill a card, a player puts the top card of their library into their graveyard.)

Wight of Precinct Six

Wight of Precinct Six gets +1/+1 for each creature card in your opponents' graveyards.

Command Tower

Drown in the Loch

Choose one —
• Counter target spell with mana value less than or equal to the number of cards in its controller's graveyard.
• Destroy target creature with mana value less than or equal to the number of cards in its controller's graveyard.

Disciple of Deceit

Inspired — Whenever Disciple of Deceit becomes untapped, you may discard a nonland card. If you do, search your library for a card with the same mana value as that card, reveal it, put it into your hand, then shuffle.

Isochron Scepter

Imprint — When Isochron Scepter enters, you may exile an instant card with mana value 2 or less from your hand.
{2}, {T}: You may copy the exiled card. If you do, you may cast the copy without paying its mana cost.

Breach the Multiverse

Each player mills ten cards. For each player, choose a creature or planeswalker card in that player's graveyard. Put those cards onto the battlefield under your control. Then each creature you control becomes a Phyrexian in addition to its other types.

Maddening Cacophony

Kicker {3}{U}
Each opponent mills eight cards. If this spell was kicked, instead each opponent mills half their library, rounded up.

Otawara, Soaring City

{T}: Add {U}.
Channel — {3}{U}, Discard Otawara, Soaring City: Return target artifact, creature, enchantment, or planeswalker to its owner's hand. This ability costs {1} less to activate for each legendary creature you control.

Reality Shift

Exile target creature. Its controller manifests the top card of their library. (That player puts the top card of their library onto the battlefield face down as a 2/2 creature. If it's a creature card, it can be turned face up any time for its mana cost.)

Nighthowler

Bestow {2}{B}{B} (If you cast this card for its bestow cost, it's an Aura spell with enchant creature. It becomes a creature again if it's not attached to a creature.)
Nighthowler and enchanted creature each get +X/+X, where X is the number of creature cards in all graveyards.

Duskmantle Guildmage

{1}{U}{B}: Whenever a card is put into an opponent's graveyard from anywhere this turn, that player loses 1 life.
{2}{U}{B}: Target player mills two cards.

Opposition Agent

Flash
You control your opponents while they're searching their libraries.
While an opponent is searching their library, they exile each card they find. You may play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast them.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Into the Story

This spell costs {3} less to cast if an opponent has seven or more cards in their graveyard.
Draw four cards.

Pongify

Destroy target creature. It can't be regenerated. Its controller creates a 3/3 green Ape creature token.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Memory Erosion

Whenever an opponent casts a spell, that player mills two cards.

Island

Scheming Symmetry

Choose two target players. Each of them searches their library for a card, then shuffles and puts that card on top.

Pemmin's Aura

Enchant creature
{U}: Untap enchanted creature.
{U}: Enchanted creature gains flying until end of turn.
{U}: Enchanted creature gains shroud until end of turn. (It can't be the target of spells or abilities.)
{1}: Enchanted creature gets +1/-1 or -1/+1 until end of turn.

Ashiok, Nightmare Muse

+1: Create a 2/3 blue and black Nightmare creature token with "Whenever this creature attacks or blocks, each opponent exiles the top two cards of their library."
−3: Return target nonland permanent to its owner's hand, then that player exiles a card from their hand.
−7: You may cast up to three spells from among face-up cards your opponents own from exile without paying their mana costs.

Tidewater Minion

Defender (This creature can't attack.)
{4}: Tidewater Minion loses defender until end of turn.
{T}: Untap target permanent.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Counterspell

Ashiok, Nightmare Weaver

+2: Exile the top three cards of target opponent's library.
−X: Put a creature card with mana value X exiled with Ashiok, Nightmare Weaver onto the battlefield under your control. That creature is a Nightmare in addition to its other types.
−10: Exile all cards from all opponents' hands and graveyards.

Lazav, Dimir Mastermind

Hexproof
Whenever a creature card is put into an opponent's graveyard from anywhere, you may have Lazav, Dimir Mastermind become a copy of that card, except its name is Lazav, Dimir Mastermind, it's legendary in addition to its other types, and it has hexproof and this ability.

Notion Thief

Flash
If an opponent would draw a card except the first one they draw in each of their draw steps, instead that player skips that draw and you draw a card.

Mind Funeral

Target opponent reveals cards from the top of their library until four land cards are revealed. That player puts all cards revealed this way into their graveyard.

Thousand-Year Elixir

You may activate abilities of creatures you control as though those creatures had haste.
{1}, {T}: Untap target creature.

Wall of Frost

Defender
Whenever Wall of Frost blocks a creature, that creature doesn't untap during its controller's next untap step.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Glacial Wall

Eater of the Dead

{0}: If Eater of the Dead is tapped, exile target creature card from a graveyard and untap Eater of the Dead.

Negate

Relic of Progenitus

{T}: Target player exiles a card from their graveyard.
{1}, Exile Relic of Progenitus: Exile all graveyards. Draw a card.

Thought Collapse

Counter target spell. Its controller mills three cards.

Drowned Catacomb

Drowned Catacomb enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Illusionist's Bracers

Whenever an ability of equipped creature is activated, if it isn't a mana ability, copy that ability. You may choose new targets for the copy.
Equip {3}

Delay

Counter target spell. If the spell is countered this way, exile it with three time counters on it instead of putting it into its owner's graveyard. If it doesn't have suspend, it gains suspend. (At the beginning of its owner's upkeep, they remove a time counter. When the last is removed, they may play it without paying its mana cost. If it's a creature, it has haste.)

Psychic Corrosion

Whenever you draw a card, each opponent mills two cards.

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Tribute Mage

When Tribute Mage enters, you may search your library for an artifact card with mana value 2, reveal that card, put it into your hand, then shuffle.

Soulless Jailer

Permanent cards in graveyards can't enter the battlefield.
Players can't cast noncreature spells from graveyards or exile.

Jace's Phantasm

Flying
Jace's Phantasm gets +4/+4 as long as an opponent has ten or more cards in their graveyard.

Visions of Beyond

Draw a card. If a graveyard has twenty or more cards in it, draw three cards instead.

Arcane Denial

Counter target spell. Its controller may draw up to two cards at the beginning of the next turn's upkeep.
You draw a card at the beginning of the next turn's upkeep.

Choked Estuary

As Choked Estuary enters, you may reveal an Island or Swamp card from your hand. If you don't, Choked Estuary enters tapped.
{T}: Add {U} or {B}.

Wall of Lost Thoughts

Defender (This creature can't attack.)
When Wall of Lost Thoughts enters, target player mills four cards. (They put the top four cards of their library into their graveyard.)

Hedron Crab

Landfall — Whenever a land you control enters, target player mills three cards.

Sire of Stagnation

Devoid (This card has no color.)
Whenever a land an opponent controls enters, that player exiles the top two cards of their library and you draw two cards.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.