Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Sol Ring

Butcher's Cleaver

Equipped creature gets +3/+0.
As long as equipped creature is a Human, it has lifelink.
Equip {3}

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Aspect of Lamprey

Enchant creature you control
When Aspect of Lamprey enters the battlefield, target opponent discards two cards.
Enchanted creature has lifelink.

Murder

Akoum Refuge

Akoum Refuge enters the battlefield tapped.
When Akoum Refuge enters the battlefield, you gain 1 life.
{T}: Add {B} or {R}.

Geth, Lord of the Vault

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
{X}{B}: Put target artifact or creature card with mana value X from an opponent's graveyard onto the battlefield under your control tapped. Then that player mills X cards.

Bedevil

Destroy target artifact, creature, or planeswalker.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Hatred

As an additional cost to cast this spell, pay X life.
Target creature gets +X/+0 until end of turn.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

City of Brass

Whenever City of Brass becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.

Curse of Fool's Wisdom

Enchant player
Whenever enchanted player draws a card, they lose 2 life and you gain 2 life.
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Fire Covenant

As an additional cost to cast this spell, pay X life.
Fire Covenant deals X damage divided as you choose among any number of target creatures.

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Unspeakable Symbol

Pay 3 life: Put a +1/+1 counter on target creature.

Darksteel Plate

Indestructible
Equipped creature has indestructible.
Equip {2}

Ob Nixilis Reignited

+1: You draw a card and you lose 1 life.
−3: Destroy target creature.
−8: Target opponent gets an emblem with "Whenever a player draws a card, you lose 2 life."

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Greven, Predator Captain

Menace
Greven, Predator Captain gets +X/+0, where X is the amount of life you've lost this turn.
Whenever Greven attacks, you may sacrifice another creature. If you do, you draw cards equal to that creature's power and you lose life equal to that creature's toughness.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Night's Whisper

Treasonous Ogre

Dethrone (Whenever this creature attacks the player with the most life or tied for most life, put a +1/+1 counter on it.)
Pay 3 life: Add {R}.

Tarnished Citadel

{T}: Add {C}.
{T}: Add one mana of any color. Tarnished Citadel deals 3 damage to you.

Ob Nixilis of the Black Oath

+2: Each opponent loses 1 life. You gain life equal to the life lost this way.
−2: Create a 5/5 black Demon creature token with flying. You lose 2 life.
−8: You get an emblem with "{1}{B}, Sacrifice a creature: You gain X life and draw X cards, where X is the sacrificed creature's power."
Ob Nixilis of the Black Oath can be your commander.

Shadowspear

Equipped creature gets +1/+1 and has trample and lifelink.
{1}: Permanents your opponents control lose hexproof and indestructible until end of turn.
Equip {2}

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Cabal Pit

{T}: Add {B}. Cabal Pit deals 1 damage to you.
Threshold — {B}, {T}, Sacrifice Cabal Pit: Target creature gets -2/-2 until end of turn. Activate only if seven or more cards are in your graveyard.

Chainer, Nightmare Adept

Discard a card: You may cast a creature spell from your graveyard this turn. Activate only once each turn.
Whenever a nontoken creature enters the battlefield under your control, if you didn't cast it from your hand, it gains haste until your next turn.

Bloodfell Caves

Bloodfell Caves enters the battlefield tapped.
When Bloodfell Caves enters the battlefield, you gain 1 life.
{T}: Add {B} or {R}.

Loxodon Warhammer

Equipped creature gets +3/+0 and has trample and lifelink.
Equip {3}

Ramunap Ruins

{T}: Add {C}.
{T}, Pay 1 life: Add {R}.
{2}{R}{R}, {T}, Sacrifice a Desert: Ramunap Ruins deals 2 damage to each opponent.

Rush of Vitality

Target creature gets +1/+0 and gains lifelink and indestructible until end of turn. (Damage dealt by that creature also causes its controller to gain that much life, and it can't be destroyed by damage or effects that say "destroy.")

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Magus of the Coffers

{2}, {T}: Add {B} for each Swamp you control.

Rakdos Locket

{T}: Add {B} or {R}.
{B/R}{B/R}{B/R}{B/R}, {T}, Sacrifice Rakdos Locket: Draw two cards.

Skeletal Scrying

As an additional cost to cast this spell, exile X cards from your graveyard.
You draw X cards and you lose X life.

Bloodtracker

Flying
{B}, Pay 2 life: Put a +1/+1 counter on Bloodtracker.
When Bloodtracker leaves the battlefield, draw a card for each +1/+1 counter on it.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Eternal Thirst

Enchant creature
Enchanted creature has lifelink and "Whenever a creature an opponent controls dies, put a +1/+1 counter on this creature." (Damage dealt by a creature with lifelink also causes its controller to gain that much life.)

Dreadbore

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Ifnir Deadlands

{T}: Add {C}.
{T}, Pay 1 life: Add {B}.
{2}{B}{B}, {T}, Sacrifice a Desert: Put two -1/-1 counters on target creature an opponent controls. Activate only as a sorcery.

Tainted Strike

Target creature gets +1/+0 and gains infect until end of turn. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Barbarian Ring

{T}: Add {R}. Barbarian Ring deals 1 damage to you.
Threshold — {R}, {T}, Sacrifice Barbarian Ring: It deals 2 damage to any target. Activate only if seven or more cards are in your graveyard.

Ill-Gotten Inheritance

At the beginning of your upkeep, Ill-Gotten Inheritance deals 1 damage to each opponent and you gain 1 life.
{5}{B}, Sacrifice Ill-Gotten Inheritance: It deals 4 damage to target opponent and you gain 4 life.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Basilisk Collar

Equipped creature has deathtouch and lifelink.
Equip {2}

Terminate

Destroy target creature. It can't be regenerated.

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. Talisman of Indulgence deals 1 damage to you.

Sonorous Howlbonder

Menace
Each creature you control with menace can't be blocked except by three or more creatures.

Bloodhall Priest

Whenever Bloodhall Priest enters the battlefield or attacks, if you have no cards in hand, Bloodhall Priest deals 2 damage to any target.
Madness {1}{B}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Ancient Tomb

{T}: Add {C}{C}. Ancient Tomb deals 2 damage to you.

Solemn Simulacrum

When Solemn Simulacrum enters the battlefield, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Labyrinth Raptor

Menace
Whenever a creature you control with menace becomes blocked, defending player sacrifices a creature blocking it.
{B}{R}: Creatures you control with menace get +1/+0 until end of turn.

Cartouche of Ambition

Enchant creature you control
When Cartouche of Ambition enters the battlefield, you may put a -1/-1 counter on target creature.
Enchanted creature gets +1/+1 and has lifelink.

Sulfurous Springs

{T}: Add {C}.
{T}: Add {B} or {R}. Sulfurous Springs deals 1 damage to you.

Swamp

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Luxury Suite

Luxury Suite enters the battlefield tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Mountain

Warstorm Surge

Whenever a creature enters the battlefield under your control, it deals damage equal to its power to any target.

From Under the Floorboards

Madness {X}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)
Create three tapped 2/2 black Zombie creature tokens and you gain 3 life. If this spell's madness cost was paid, instead create X of those tokens and you gain X life.

Sign in Blood

Target player draws two cards and loses 2 life.

Rakdos Carnarium

Rakdos Carnarium enters the battlefield tapped.
When Rakdos Carnarium enters the battlefield, return a land you control to its owner's hand.
{T}: Add {B}{R}.

Smoldering Marsh

({T}: Add {B} or {R}.)
Smoldering Marsh enters the battlefield tapped unless you control two or more basic lands.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}