Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Painful Lesson

Target player draws two cards and loses 2 life.

Pristine Talisman

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Pili-Pala

Flying
{2}, {Q}: Add one mana of any color. ({Q} is the untap symbol.)

Darksteel Plate

Indestructible
Equipped creature has indestructible.
Equip {2}

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Mikokoro, Center of the Sea

{T}: Add {C}.
{2}, {T}: Each player draws a card.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Have

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent of their choice that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Dark Ritual

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Essence Pulse

You gain 2 life. Each creature gets -X/-X until end of turn, where X is the amount of life you gained this turn.

Ob Nixilis Reignited

+1: You draw a card and you lose 1 life.
−3: Destroy target creature.
−8: Target opponent gets an emblem with "Whenever a player draws a card, you lose 2 life."

Sol Ring

Elixir of Immortality

{2}, {T}: You gain 5 life. Shuffle Elixir of Immortality and your graveyard into their owner's library.

Knight of Dusk's Shadow

Menace (This creature can't be blocked except by two or more creatures.)
Your opponents can't gain life.
{1}{B}: Knight of Dusk's Shadow gets +1/+1 until end of turn.

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Master of the Feast

Flying
At the beginning of your upkeep, each opponent draws a card.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Deadly Dispute

As an additional cost to cast this spell, sacrifice an artifact or creature.
Draw two cards and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Pact of the Serpent

Choose a creature type. Target player draws X cards and loses X life, where X is the number of creatures they control of the chosen type.

Howling Mine

At the beginning of each player's draw step, if Howling Mine is untapped, that player draws an additional card.

Atrocious Experiment

Target player mills two cards, draws two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Gix, Yawgmoth Praetor

Whenever a creature deals combat damage to one of your opponents, its controller may pay 1 life. If they do, they draw a card.
{4}{B}{B}{B}, Discard X cards: Exile the top X cards of target opponent's library. You may play lands and cast spells from among cards exiled this way without paying their mana costs.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Baleful Mastery

You may pay {1}{B} rather than pay this spell's mana cost.
If the {1}{B} cost was paid, an opponent draws a card.
Exile target creature or planeswalker.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Night's Whisper

Font of Mythos

At the beginning of each player's draw step, that player draws two additional cards.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Blood Pact

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis, the Hate-Twisted deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Swamp

Wretched Confluence

Choose three. You may choose the same mode more than once.
• Target player draws a card and loses 1 life.
• Target creature gets -2/-2 until end of turn.
• Return target creature card from your graveyard to your hand.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Arcane Signet

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Greed

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

The Cruelty of Gix

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.
II — Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.
III — Put target creature card from a graveyard onto the battlefield under your control.

Vraan, Executioner Thane

Whenever one or more other creatures you control die, each opponent loses 2 life and you gain 2 life. This ability triggers only once each turn.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Study Hall

{T}: Add {C}.
{1}, {T}: Add one mana of any color. When you spend this mana to cast your commander, scry X, where X is the number of times it's been cast from the command zone this game.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Hero's Downfall

No Mercy

Whenever a creature deals damage to you, destroy it.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Ring of Xathrid

{2}: Regenerate equipped creature. (The next time that creature would be destroyed this turn, instead tap it, remove it from combat, and heal all damage on it.)
At the beginning of your upkeep, put a +1/+1 counter on equipped creature if it's black.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Temporal Extortion

When you cast this spell, any player may pay half their life, rounded up. If a player does, counter Temporal Extortion.
Take an extra turn after this one.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.

Temple Bell

Eldritch Pact

Target player draws X cards and loses X life, where X is the number of cards in their graveyard.

Radiant Fountain

When Radiant Fountain enters, you gain 2 life.
{T}: Add {C}.

The True Scriptures

(As this Saga enters and after your draw step, add a lore counter.)
I — For each opponent, destroy up to one target creature or planeswalker that player controls.
II — Each opponent discards three cards, then mills three cards.
III — Put all creature cards from all graveyards onto the battlefield under your control. Exile The True Scriptures, then return it to the battlefield (front face up).

Sheoldred

Menace
When Sheoldred enters, each opponent sacrifices a nontoken creature or planeswalker of their choice.
{4}{B}: Exile Sheoldred, then return it to the battlefield transformed under its owner's control. Activate only as a sorcery and only if an opponent has eight or more cards in their graveyard.

Sheoldred // The True Scriptures

Damnable Pact

Target player draws X cards and loses X life.

Elder Brain

Menace
Whenever Elder Brain attacks a player, exile all cards from that player's hand, then they draw that many cards. You may play lands and cast spells from among the exiled cards for as long as they remain exiled. If you cast a spell this way, you may spend mana as though it were mana of any color to cast it.

Ambition's Cost

You draw three cards and you lose 3 life.

Teferi's Puzzle Box

At the beginning of each player's draw step, that player puts the cards in their hand on the bottom of their library in any order, then draws that many cards.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Barad-dûr

Barad-dûr enters tapped unless you control a legendary creature.
{T}: Add {B}.
{X}{X}{B}, {T}: Amass Orcs X. Activate only if a creature died this turn.

Phyrexian Obliterator

Trample
Whenever a source deals damage to Phyrexian Obliterator, that source's controller sacrifices that many permanents of their choice.

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.