Kokusho, the Evening Star

Flying
When Kokusho, the Evening Star dies, each opponent loses 5 life. You gain life equal to the life lost this way.

Cauldron Familiar

When Cauldron Familiar enters the battlefield, each opponent loses 1 life and you gain 1 life.
Sacrifice a Food: Return Cauldron Familiar from your graveyard to the battlefield.

Garruk, Cursed Huntsman

0: Create two 2/2 black and green Wolf creature tokens with "When this creature dies, put a loyalty counter on each Garruk you control."
−3: Destroy target creature. Draw a card.
−6: You get an emblem with "Creatures you control get +3/+3 and have trample."

Skittering Invasion

Create five 0/1 colorless Eldrazi Spawn creature tokens. They have "Sacrifice this creature: Add {C}."

Thieving Amalgam

At the beginning of each opponent's upkeep, you manifest the top card of that player's library. (Put it onto the battlefield face down as a 2/2 creature. Turn it face up any time for its mana cost if it's a creature card.)
Whenever a creature you control but don't own dies, its owner loses 2 life and you gain 2 life.

Vicious Conquistador

Whenever Vicious Conquistador attacks, each opponent loses 1 life.

Dawnglade Regent

When Dawnglade Regent enters the battlefield, you become the monarch.
As long as you're the monarch, permanents you control have hexproof.

Hopeless Nightmare

When Hopeless Nightmare enters the battlefield, each opponent discards a card and loses 2 life.
When Hopeless Nightmare is put into a graveyard from the battlefield, scry 2.
{2}{B}: Sacrifice Hopeless Nightmare.

Awaken the Woods

Create X 1/1 green Forest Dryad land creature tokens. (They're affected by summoning sickness.)

Overwhelming Forces

Destroy all creatures target opponent controls. Draw a card for each creature destroyed this way.

Stonecoil Serpent

Reach, trample, protection from multicolored
Stonecoil Serpent enters the battlefield with X +1/+1 counters on it.

Elder Brain

Menace
Whenever Elder Brain attacks a player, exile all cards from that player's hand, then they draw that many cards. You may play lands and cast spells from among the exiled cards for as long as they remain exiled. If you cast a spell this way, you may spend mana as though it were mana of any color to cast it.

Sower of Discord

Flying
As Sower of Discord enters the battlefield, choose two players.
Whenever damage is dealt to one of the chosen players, the other chosen player also loses that much life.

Vampire Neonate

{2}, {T}: Each opponent loses 1 life and you gain 1 life.

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Apex Altisaur

When Apex Altisaur enters the battlefield, it fights up to one target creature you don't control.
Enrage — Whenever Apex Altisaur is dealt damage, it fights up to one target creature you don't control.

Phyrexian Fleshgorger

Prototype {1}{B}{B} — 3/3 (You may cast this spell with different mana cost, color, and size. It keeps its abilities and types.)
Menace, lifelink
Ward—Pay life equal to Phyrexian Fleshgorger's power.

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Vorinclex, Voice of Hunger

Trample
Whenever you tap a land for mana, add one mana of any type that land produced.
Whenever an opponent taps a land for mana, that land doesn't untap during its controller's next untap step.

Pulse Tracker

Whenever Pulse Tracker attacks, each opponent loses 1 life.

Breach the Multiverse

Each player mills ten cards. For each player, choose a creature or planeswalker card in that player's graveyard. Put those cards onto the battlefield under your control. Then each creature you control becomes a Phyrexian in addition to its other types.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Kindred Dominance

Choose a creature type. Destroy all creatures that aren't of the chosen type.

Myojin of Towering Might

Myojin of Towering Might enters the battlefield with an indestructible counter on it if you cast it from your hand.
Remove an indestructible counter from Myojin of Towering Might: Distribute eight +1/+1 counters among any number of target creatures you control. They gain trample until end of turn.

Belbe, Corrupted Observer

At the beginning of each player's postcombat main phase, that player adds {C}{C} for each of your opponents who lost life this turn. (Damage causes loss of life.)

Genesis Wave

Reveal the top X cards of your library. You may put any number of permanent cards with mana value X or less from among them onto the battlefield. Then put all cards revealed this way that weren't put onto the battlefield into your graveyard.

God-Pharaoh's Statue

Spells your opponents cast cost {2} more to cast.
At the beginning of your end step, each opponent loses 1 life.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Dreg Recycler

{T}, Sacrifice an artifact or creature: Each opponent loses 1 life and you gain 1 life.

Portal to Phyrexia

When Portal to Phyrexia enters the battlefield, each opponent sacrifices three creatures.
At the beginning of your upkeep, put target creature card from a graveyard onto the battlefield under your control. It's a Phyrexian in addition to its other types.

Moldgraf Monstrosity

Trample
When Moldgraf Monstrosity dies, exile it, then return two creature cards at random from your graveyard to the battlefield.

Bane of Progress

When Bane of Progress enters the battlefield, destroy all artifacts and enchantments. Put a +1/+1 counter on Bane of Progress for each permanent destroyed this way.

Kaldra Compleat

Living weapon
Indestructible
Equipped creature gets +5/+5 and has first strike, trample, indestructible, haste, and "Whenever this creature deals combat damage to a creature, exile that creature."
Equip {7}

Necrotic Hex

Each player sacrifices six creatures. You create six tapped 2/2 black Zombie creature tokens.

Carnage Tyrant

This spell can't be countered.
Trample, hexproof

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Zendikar Resurgent

Whenever you tap a land for mana, add one mana of any type that land produced. (The types of mana are white, blue, black, red, green, and colorless.)
Whenever you cast a creature spell, draw a card.

Elderscale Wurm

Trample
When Elderscale Wurm enters the battlefield, if your life total is less than 7, your life total becomes 7.
As long as you have 7 or more life, damage that would reduce your life total to less than 7 reduces it to 7 instead.

Night Market Lookout

Whenever Night Market Lookout becomes tapped, each opponent loses 1 life and you gain 1 life.

Nezumi Road Captain

Menace
Vehicles you control have menace. (They can't be blocked except by two or more creatures.)

Okiba Reckoner Raid

(As this Saga enters and after your draw step, add a lore counter.)
I, II — Each opponent loses 1 life and you gain 1 life.
III — Exile this Saga, then return it to the battlefield transformed under your control.

Okiba Reckoner Raid // Nezumi Road Captain

Thornbow Archer

Whenever Thornbow Archer attacks, each opponent who doesn't control an Elf loses 1 life.

Eldrazi Conscription

Enchant creature
Enchanted creature gets +10/+10 and has trample and annihilator 2. (Whenever it attacks, defending player sacrifices two permanents.)

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Forest

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Ezuri's Predation

For each creature your opponents control, create a 4/4 green Phyrexian Beast creature token. Each of those tokens fights a different one of those creatures.

Sanctum of Stone Fangs

At the beginning of your precombat main phase, each opponent loses X life and you gain X life, where X is the number of Shrines you control.

Harvester of Souls

Deathtouch
Whenever another nontoken creature dies, you may draw a card.

Nissa's Renewal

Search your library for up to three basic land cards, put them onto the battlefield tapped, then shuffle. You gain 7 life.

Giant Adephage

Trample
Whenever Giant Adephage deals combat damage to a player, create a token that's a copy of Giant Adephage.

Herald of Leshrac

Flying
Cumulative upkeep—Gain control of a land you don't control. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
Herald of Leshrac gets +1/+1 for each land you control but don't own.
When Herald of Leshrac leaves the battlefield, each player gains control of each land they own that you control.

Archfiend of Spite

Flying
Whenever a source an opponent controls deals damage to Archfiend of Spite, that source's controller loses that much life unless they sacrifice that many permanents.
Madness {3}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Overseer of the Damned

Flying
When Overseer of the Damned enters the battlefield, you may destroy target creature.
Whenever a nontoken creature an opponent controls dies, create a tapped 2/2 black Zombie creature token.

Chromatic Orrery

You may spend mana as though it were mana of any color.
{T}: Add {C}{C}{C}{C}{C}.
{5}, {T}: Draw a card for each color among permanents you control.

Garenbrig Growth

Return target creature or land card from your graveyard to your hand. (Then exile this card. You may cast the enchantment later from exile.)

Virtue of Strength

If you tap a basic land for mana, it produces three times as much of that mana instead.

Virtue of Strength // Garenbrig Growth

Garruk, Apex Predator

+1: Destroy another target planeswalker.
+1: Create a 3/3 black Beast creature token with deathtouch.
−3: Destroy target creature. You gain life equal to its toughness.
−8: Target opponent gets an emblem with "Whenever a creature attacks you, it gets +5/+5 and gains trample until end of turn."

Brainstealer Dragon

Flying
At the beginning of your end step, exile the top card of each opponent's library. You may play those cards for as long as they remain exiled. If you cast a spell this way, you may spend mana as though it were mana of any color to cast it.
Whenever a nonland permanent an opponent owns enters the battlefield under your control, they lose life equal to its mana value.

Titania's Command

Choose two —
• Exile target player's graveyard. You gain 1 life for each card exiled this way.
• Search your library for up to two land cards, put them onto the battlefield tapped, then shuffle.
• Create two 2/2 green Bear creature tokens.
• Put two +1/+1 counters on each creature you control.

Emergent Woodwurm

Backup 3 (When this creature enters the battlefield, put three +1/+1 counters on target creature. If that's another creature, it gains the following ability until end of turn.)
Whenever this creature attacks, look at the top X cards of your library, where X is its power. You may put a permanent card with mana value X or less from among them onto the battlefield. Put the rest on the bottom of your library in a random order.

The World Spell

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I, II — Look at the top seven cards of your library. You may reveal a non-Saga permanent card from among them and put it into your hand. Put the rest on the bottom of your library in a random order.
III — Put up to two non-Saga permanent cards from your hand onto the battlefield.

Mardu Shadowspear

Whenever Mardu Shadowspear attacks, each opponent loses 1 life.
Dash {1}{B} (You may cast this spell for its dash cost. If you do, it gains haste, and it's returned from the battlefield to its owner's hand at the beginning of the next end step.)

Vraska, Relic Seeker

+2: Create a 2/2 black Pirate creature token with menace.
−3: Destroy target artifact, creature, or enchantment. Create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
−10: Target player's life total becomes 1.

Ugin, the Spirit Dragon

+2: Ugin, the Spirit Dragon deals 3 damage to any target.
−X: Exile each permanent with mana value X or less that's one or more colors.
−10: You gain 7 life, draw seven cards, then put up to seven permanent cards from your hand onto the battlefield.

Myojin of Night's Reach

Myojin of Night's Reach enters the battlefield with a divinity counter on it if you cast it from your hand.
Myojin of Night's Reach has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Night's Reach: Each opponent discards their hand.

Gonti's Machinations

Whenever you lose life for the first time each turn, you get {E}. (You get an energy counter. Damage causes loss of life.)
Pay {E}{E}, Sacrifice Gonti's Machinations: Each opponent loses 3 life. You gain life equal to the life lost this way.

Myojin of Life's Web

Myojin of Life's Web enters the battlefield with a divinity counter on it if you cast it from your hand.
Myojin of Life's Web has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Life's Web: Put any number of creature cards from your hand onto the battlefield.

Hydra Broodmaster

{X}{X}{G}: Monstrosity X. (If this creature isn't monstrous, put X +1/+1 counters on it and it becomes monstrous.)
When Hydra Broodmaster becomes monstrous, create X X/X green Hydra creature tokens.

Void Winnower

Your opponents can't cast spells with even mana values. (Zero is even.)
Your opponents can't block with creatures with even mana values.

Archon of Cruelty

Flying
Whenever Archon of Cruelty enters the battlefield or attacks, target opponent sacrifices a creature or planeswalker, discards a card, and loses 3 life. You draw a card and gain 3 life.

Desecrate Reality

For each opponent, exile up to one target permanent that player controls with an even mana value. (Zero is even.)
Adamant — If at least three colorless mana was spent to cast this spell, return a permanent card with an odd mana value from your graveyard to the battlefield.

Phyrexian Triniform

When Phyrexian Triniform dies, create three 3/3 colorless Phyrexian Golem artifact creature tokens.
Encore {12} ({12}, Exile this card from your graveyard: For each opponent, create a token copy that attacks that opponent this turn if able. They gain haste. Sacrifice them at the beginning of the next end step. Activate only as a sorcery.)

Raised by Giants

Commander creatures you own have base power and toughness 10/10 and are Giants in addition to their other types.

Loreseeker's Stone

{3}, {T}: Draw three cards. This ability costs {1} more to activate for each card in your hand.

Herald of Anguish

Improvise (Your artifacts can help cast this spell. Each artifact you tap after you're done activating mana abilities pays for {1}.)
Flying
At the beginning of your end step, each opponent discards a card.
{1}{B}, Sacrifice an artifact: Target creature gets -2/-2 until end of turn.

Liliana, Dreadhorde General

Whenever a creature you control dies, draw a card.
+1: Create a 2/2 black Zombie creature token.
−4: Each player sacrifices two creatures.
−9: Each opponent chooses a permanent they control of each permanent type and sacrifices the rest.

Geth, Lord of the Vault

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
{X}{B}: Put target artifact or creature card with mana value X from an opponent's graveyard onto the battlefield under your control tapped. Then that player mills X cards.