Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Plains

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Pristine Talisman

Despark

Exile target permanent with mana value 4 or greater.

Utter End

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Feast of the Victorious Dead

At the beginning of your end step, if one or more creatures died this turn, you gain that much life and distribute that many +1/+1 counters among creatures you control.

Shard of the Nightbringer

Flying
Drain Life — When Shard of the Nightbringer enters, if you cast it, target opponent loses half their life, rounded up. You gain life equal to the life lost this way.

Sol Ring

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Dire Fleet Ravager

Menace, deathtouch
When Dire Fleet Ravager enters, each player loses a third of their life, rounded up.

Temple of Silence

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {W} or {B}.

Swamp

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Orzhov Signet

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Mortify

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Glass-Cast Heart

Whenever one or more Vampires you control attack, create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")
{B}, {T}, Pay 1 life: Create a 1/1 white and black Vampire creature token with lifelink.
{B}{B}, {T}, Sacrifice Glass-Cast Heart and thirteen Blood tokens: Each opponent loses 13 life and you gain 13 life.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Markov Purifier

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay {2}. If you do, draw a card.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Blood Tribute

Kicker—Tap an untapped Vampire you control. (You may tap a Vampire you control in addition to any other costs as you cast this spell.)
Target opponent loses half their life, rounded up. If this spell was kicked, you gain life equal to the life lost this way.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Reliquary Monk

When Reliquary Monk dies, destroy target artifact or enchantment.

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Quietus Spike

Equipped creature has deathtouch.
Whenever equipped creature deals combat damage to a player, that player loses half their life, rounded up.
Equip {3}

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Death Grasp

Death Grasp deals X damage to any target. You gain X life.

Kaya, Intangible Slayer

Hexproof
+2: Each opponent loses 3 life and you gain 3 life.
0: You draw two cards. Then each opponent may scry 1.
−3: Exile target creature or enchantment. If it wasn't an Aura, create a token that's a copy of it, except it's a 1/1 white Spirit creature with flying in addition to its other types.

Greed

Anointed Deacon

At the beginning of combat on your turn, you may have target Vampire get +2/+0 until end of turn.

Bishop's Soldier

Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Vampire Nighthawk

Flying
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Daxos, Blessed by the Sun

Daxos's toughness is equal to your devotion to white. (Each {W} in the mana costs of permanents you control counts toward your devotion to white.)
Whenever another creature you control enters or dies, you gain 1 life.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Warlock Class

(Gain the next level as a sorcery to add its ability.)
At the beginning of your end step, if a creature died this turn, each opponent loses 1 life.
{1}{B}: Level 2
When this Class becomes level 2, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
{6}{B}: Level 3
At the beginning of your end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Scytheclaw

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +1/+1.
Whenever equipped creature deals combat damage to a player, that player loses half their life, rounded up.
Equip {3}

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Markov Baron

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Lifelink
Other Vampires you control get +1/+1.
Madness {2}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Astarion's Thirst

Exile target creature. Put X +1/+1 counters on a commander creature you control, where X is the power of the creature exiled this way.

Blood Glutton

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Bishop of Rebirth

Vigilance
Whenever Bishop of Rebirth attacks, you may return target creature card with mana value 3 or less from your graveyard to the battlefield.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Arcane Signet

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Scoured Barrens

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {W} or {B}.

Stroke of Midnight

Destroy target nonland permanent. Its controller creates a 1/1 white Human creature token.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Scourge of the Skyclaves

Kicker {4}{B}
When you cast this spell, if it was kicked, each player loses half their life, rounded up.
Scourge of the Skyclaves's power and toughness are each equal to 20 minus the highest life total among players.

Arvad the Cursed

Deathtouch, lifelink
Other legendary creatures you control get +2/+2.

Cleric Class

(Gain the next level as a sorcery to add its ability.)
If you would gain life, you gain that much life plus 1 instead.
{3}{W}: Level 2
Whenever you gain life, put a +1/+1 counter on target creature you control.
{4}{W}: Level 3
When this Class becomes level 3, return target creature card from your graveyard to the battlefield. You gain life equal to that creature's toughness.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Helm of the Host

At the beginning of combat on your turn, create a token that's a copy of equipped creature, except the token isn't legendary. That token gains haste.
Equip {5}