Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Citywide Bust

Destroy all creatures with toughness 4 or greater.

Terminus

Put all creatures on the bottom of their owners' libraries.
Miracle {W} (You may cast this card for its miracle cost when you draw it if it's the first card you drew this turn.)

Dawn

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Return all creature cards with power 2 or less from your graveyard to your hand.

Dusk

Destroy all creatures with power 3 or greater.

Dusk // Dawn

Purify

Oblivion Stone

{4}, {T}: Put a fate counter on target permanent.
{5}, {T}, Sacrifice Oblivion Stone: Destroy each nonland permanent without a fate counter on it, then remove all fate counters from all permanents.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

March of Souls

Destroy all creatures. They can't be regenerated. For each creature destroyed this way, its controller creates a 1/1 white Spirit creature token with flying.

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Time Wipe

Return a creature you control to its owner's hand, then destroy all creatures.

Hour of Reckoning

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy all nontoken creatures.

Final Judgment

Day of Judgment

Akroma's Vengeance

Destroy all artifacts, creatures, and enchantments.
Cycling {3} ({3}, Discard this card: Draw a card.)

Planar Cleansing

All Is Dust

Each player sacrifices all permanents they control that are one or more colors.

Shatterstorm

Destroy all artifacts. They can't be regenerated.

Overwhelming Forces

Destroy all creatures target opponent controls. Draw a card for each creature destroyed this way.

Martial Coup

Create X 1/1 white Soldier creature tokens. If X is 5 or more, destroy all other creatures.

Child of Alara

Trample
When Child of Alara dies, destroy all nonland permanents. They can't be regenerated.

Play of the Game

Assist (Another player can pay up to {6} of this spell's cost.)
Exile all nonland permanents.

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.