Depopulate

Each player who controls a multicolored creature draws a card. Then destroy all creatures.

Isolation Cell

Whenever an opponent casts a creature spell, that player loses 2 life unless they pay {2}.

Rhystic Deluge

{U}: Tap target creature unless its controller pays {1}.

Kasmina, Enigmatic Mentor

Spells your opponents cast that target a creature or planeswalker you control cost {2} more to cast.
−2: Create a 2/2 blue Wizard creature token. Draw a card, then discard a card.

Kami of the Crescent Moon

At the beginning of each player's draw step, that player draws an additional card.

Sunscorch Regent

Flying
Whenever an opponent casts a spell, put a +1/+1 counter on Sunscorch Regent and you gain 1 life.

Thran Dynamo

Plains

Grand Arbiter Augustin IV

White spells you cast cost {1} less to cast.
Blue spells you cast cost {1} less to cast.
Spells your opponents cast cost {1} more to cast.

Aura of Silence

Artifact and enchantment spells your opponents cast cost {2} more to cast.
Sacrifice Aura of Silence: Destroy target artifact or enchantment.

Leyline of Sanctity

If Leyline of Sanctity is in your opening hand, you may begin the game with it on the battlefield.
You have hexproof. (You can't be the target of spells or abilities your opponents control.)

Thalia, Guardian of Thraben

First strike
Noncreature spells cost {1} more to cast.

Dream Tides

Creatures don't untap during their controllers' untap steps.
At the beginning of each player's upkeep, that player may choose any number of tapped nongreen creatures they control and pay {2} for each creature chosen this way. If the player does, untap those creatures.

God-Pharaoh's Statue

Spells your opponents cast cost {2} more to cast.
At the beginning of your end step, each opponent loses 1 life.

Azorius Signet

Damping Sphere

If a land is tapped for two or more mana, it produces {C} instead of any other type and amount.
Each spell a player casts costs {1} more to cast for each other spell that player has cast this turn.

Gold-Forged Thopteryx

Flying, lifelink
Each legendary permanent you control has ward {2}. (Whenever it becomes the target of a spell or ability an opponent controls, counter it unless that player pays {2}.)

Azorius Locket

{T}: Add {W} or {U}.
{W/U}{W/U}{W/U}{W/U}, {T}, Sacrifice Azorius Locket: Draw two cards.

Sky Diamond

White Sun's Twilight

You gain X life. Create X 1/1 colorless Phyrexian Mite artifact creature tokens with toxic 1 and "This creature can't block." If X is 5 or more, destroy all other creatures. (Players dealt combat damage by a creature with toxic 1 also get a poison counter.)

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Pentarch Ward

Enchant creature
As Pentarch Ward enters, choose a color.
When Pentarch Ward enters, draw a card.
Enchanted creature has protection from the chosen color. This effect doesn't remove Pentarch Ward.

Talisman of Progress

{T}: Add {C}.
{T}: Add {W} or {U}. Talisman of Progress deals 1 damage to you.

Amulet of Safekeeping

Whenever you become the target of a spell or ability an opponent controls, counter that spell or ability unless its controller pays {1}.
Creature tokens get -1/-0.

Circle of Protection: Green

{1}: The next time a green source of your choice would deal damage to you this turn, prevent that damage.

Sol Ring

Gift of Estates

If an opponent controls more lands than you, search your library for up to three Plains cards, reveal them, put them into your hand, then shuffle.

Ghostly Prison

Windborn Muse

Flying
Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Valkmira, Protector's Shield

If a source an opponent controls would deal damage to you or a permanent you control, prevent 1 of that damage.
Whenever you or another permanent you control becomes the target of a spell or ability an opponent controls, counter that spell or ability unless its controller pays {1}.

Reidane, God of the Worthy

Flying, vigilance
Snow lands your opponents control enter tapped.
Noncreature spells your opponents cast with mana value 4 or greater cost {2} more to cast.

Reidane, God of the Worthy // Valkmira, Protector's Shield

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Feroz's Ban

Island

Monastery Siege

As Monastery Siege enters, choose Khans or Dragons.
• Khans — At the beginning of your draw step, draw an additional card, then discard a card.
• Dragons — Spells your opponents cast that target you or a permanent you control cost {2} more to cast.

Aether Barrier

Whenever a player casts a creature spell, that player sacrifices a permanent unless they pay {1}.

Disrupt

Counter target instant or sorcery spell unless its controller pays {1}.
Draw a card.

Baird, Steward of Argive

Vigilance
Creatures can't attack you or planeswalkers you control unless their controller pays {1} for each of those creatures.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Kwain, Itinerant Meddler

{T}: Each player may draw a card, then each player who drew a card this way gains 1 life.

Spelltithe Enforcer

Whenever an opponent casts a spell, that player sacrifices a permanent unless they pay {1}.

Circle of Protection: Red

{1}: The next time a red source of your choice would deal damage to you this turn, prevent that damage.

Mana Leak

Counter target spell unless its controller pays {3}.

Quantum Misalignment

Create a token that's a copy of target creature you control, except it isn't legendary.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Suspension Field

When Suspension Field enters, you may exile target creature with toughness 3 or greater until Suspension Field leaves the battlefield. (That creature returns under its owner's control.)

Dovin, Hand of Control

Artifact, instant, and sorcery spells your opponents cast cost {1} more to cast.
−1: Until your next turn, prevent all damage that would be dealt to and dealt by target permanent an opponent controls.

Trade Secrets

Target opponent draws two cards, then you draw up to four cards. That opponent may repeat this process as many times as they choose.

Magus of the Tabernacle

All creatures have "At the beginning of your upkeep, sacrifice this creature unless you pay {1}."

Vryn Wingmare

Flying
Noncreature spells cost {1} more to cast.

Quick Study

Day of Judgment

Circle of Protection: White

{1}: The next time a white source of your choice would deal damage to you this turn, prevent that damage.

Benevolent Blessing

Flash
Enchant creature
As Benevolent Blessing enters, choose a color.
Enchanted creature has protection from the chosen color. This effect doesn't remove Auras and Equipment you control that are already attached to it.

Circle of Protection: Blue

{1}: The next time a blue source of your choice would deal damage to you this turn, prevent that damage.

Midnight Clock

{T}: Add {U}.
{2}{U}: Put an hour counter on Midnight Clock.
At the beginning of each upkeep, put an hour counter on Midnight Clock.
When the twelfth hour counter is put on Midnight Clock, shuffle your hand and graveyard into your library, then draw seven cards. Exile Midnight Clock.

Circle of Protection: Black

{1}: The next time a black source of your choice would deal damage to you this turn, prevent that damage.

Archon of Absolution

Flying
Protection from white (This creature can't be blocked, targeted, dealt damage, enchanted, or equipped by anything white.)
Creatures can't attack you or planeswalkers you control unless their controller pays {1} for each of those creatures.

Citywide Bust

Destroy all creatures with toughness 4 or greater.

Marble Diamond

Marble Diamond enters tapped.
{T}: Add {W}.

Academy Loremaster

At the beginning of each player's draw step, that player may draw an additional card. If they do, spells they cast this turn cost {2} more to cast.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Thorn of Amethyst

Noncreature spells cost {1} more to cast.

Armageddon

Lion Sash

{W}: Exile target card from a graveyard. If it was a permanent card, put a +1/+1 counter on Lion Sash.
Equipped creature gets +1/+1 for each +1/+1 counter on Lion Sash.
Reconfigure {2} ({2}: Attach to target creature you control; or unattach from a creature. Reconfigure only as a sorcery. While attached, this isn't a creature.)

The Wanderer

Prevent all noncombat damage that would be dealt to you and other permanents you control.
−2: Exile target creature with power 4 or greater.