Archfiend of Depravity

Flying
At the beginning of each opponent's end step, that player chooses up to two creatures they control, then sacrifices the rest.

Gixian Puppeteer

Whenever you draw your second card each turn, each opponent loses 2 life and you gain 2 life.
When Gixian Puppeteer dies, return another target creature card with mana value 3 or less from your graveyard to the battlefield.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Bilious Skulldweller

Deathtouch
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Dross Skullbomb

{1}, Sacrifice Dross Skullbomb: Draw a card.
{2}{B}, Sacrifice Dross Skullbomb: Return target creature card from your graveyard to your hand. Draw a card. Activate only as a sorcery.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Blightbelly Rat

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Blightbelly Rat dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Bloodhusk Ritualist

Multikicker {B} (You may pay an additional {B} any number of times as you cast this spell.)
When Bloodhusk Ritualist enters the battlefield, target opponent discards a card for each time it was kicked.

Swamp

Blood Fountain

When Blood Fountain enters the battlefield, create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")
{3}{B}, {T}, Sacrifice Blood Fountain: Return up to two target creature cards from your graveyard to your hand.

Radiant Fountain

When Radiant Fountain enters the battlefield, you gain 2 life.
{T}: Add {C}.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Leyline of the Void

If Leyline of the Void is in your opening hand, you may begin the game with it on the battlefield.
If a card would be put into an opponent's graveyard from anywhere, exile it instead.

Dreadhound

When Dreadhound enters the battlefield, mill three cards. (Put the top three cards of your library into your graveyard.)
Whenever a creature dies or a creature card is put into a graveyard from a library, each opponent loses 1 life.

Hopeless Nightmare

When Hopeless Nightmare enters the battlefield, each opponent discards a card and loses 2 life.
When Hopeless Nightmare is put into a graveyard from the battlefield, scry 2.
{2}{B}: Sacrifice Hopeless Nightmare.

Emergency Weld

Return target artifact or creature card from your graveyard to your hand. Create a 1/1 colorless Soldier artifact creature token.

God-Pharaoh's Statue

Spells your opponents cast cost {2} more to cast.
At the beginning of your end step, each opponent loses 1 life.

Grave Pact

Whenever a creature you control dies, each other player sacrifices a creature.

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Typhoid Rats

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)

Knight of the Ebon Legion

{2}{B}: Knight of the Ebon Legion gets +3/+3 and gains deathtouch until end of turn.
At the beginning of your end step, if a player lost 4 or more life this turn, put a +1/+1 counter on Knight of the Ebon Legion. (Damage causes loss of life.)

Animus of Night's Reach

Menace (This creature can't be blocked except by two or more creatures.)
Whenever Animus of Night's Reach attacks, it gets +X/+0 until end of turn, where X is the number of creature cards in defending player's graveyard.

The Long Reach of Night

(As this Saga enters and after your draw step, add a lore counter.)
I, II — Each opponent sacrifices a creature unless they discard a card.
III — Exile this Saga, then return it to the battlefield transformed under your control.

The Long Reach of Night // Animus of Night's Reach

Lash of Thorns

Target creature gets +2/+1 and gains deathtouch until end of turn.

Blight Keeper

Flying
{7}{B}, {T}, Sacrifice Blight Keeper: Target opponent loses 4 life and you gain 4 life.

Locthwain Scorn

Target creature gets -3/-3 until end of turn. You gain 2 life.

Virtue of Persistence

At the beginning of your upkeep, put target creature card from a graveyard onto the battlefield under your control.

Virtue of Persistence // Locthwain Scorn

Duskhunter Bat

Bloodthirst 1 (If an opponent was dealt damage this turn, this creature enters the battlefield with a +1/+1 counter on it.)
Flying

Polluted Bonds

Whenever a land enters the battlefield under an opponent's control, that player loses 2 life and you gain 2 life.

Sanitarium Skeleton

{2}{B}: Return Sanitarium Skeleton from your graveyard to your hand.

Gloom Sower

Whenever Gloom Sower becomes blocked by a creature, that creature's controller loses 2 life and you gain 2 life.

Spiked Pit Trap

Flash
{5}, {T}, Sacrifice Spiked Pit Trap: Choose target creature, then roll a d20.
1—9 | Spiked Pit Trap deals 5 damage to that creature.
10—20 | Spiked Pit Trap deals 5 damage to that creature. Create a Treasure token.

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Faerie Dreamthief

Flying
When Faerie Dreamthief enters the battlefield, surveil 1. (Look at the top card of your library. You may put it into your graveyard.)
{2}{B}, Exile Faerie Dreamthief from your graveyard: You draw a card and you lose 1 life.

Etched Familiar

When Etched Familiar dies, each opponent loses 2 life and you gain 2 life.

Banehound

Serrated Scorpion

When Serrated Scorpion dies, it deals 2 damage to each opponent and you gain 2 life.

Pestilent Syphoner

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Skittering Heartstopper

{B}: Skittering Heartstopper gains deathtouch until end of turn.

Scion of Halaster

Commander creatures you own have "The first time you would draw a card each turn, instead look at the top two cards of your library. Put one of them into your graveyard and the other back on top of your library. Then draw a card."

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Ornithopter

Battle-Rage Blessing

Target creature gains deathtouch and indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Gulping Scraptrap

When Gulping Scraptrap enters the battlefield or dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Open the Graves

Whenever a nontoken creature you control dies, create a 2/2 black Zombie creature token.

Falkenrath Noble

Flying
Whenever Falkenrath Noble or another creature dies, target player loses 1 life and you gain 1 life.

Alchemist's Gift

Target creature gets +1/+1 and gains your choice of deathtouch or lifelink until end of turn. (Any amount of damage a creature with deathtouch deals to a creature is enough to destroy it. Damage dealt by a creature with lifelink also causes its controller to gain that much life.)

Liliana, Dreadhorde General

Whenever a creature you control dies, draw a card.
+1: Create a 2/2 black Zombie creature token.
−4: Each player sacrifices two creatures.
−9: Each opponent chooses a permanent they control of each permanent type and sacrifices the rest.

Boot Nipper

Boot Nipper enters the battlefield with your choice of a deathtouch counter or a lifelink counter on it.

Fetid Imp

Flying
{B}: Fetid Imp gains deathtouch until end of turn. (Any amount of damage it deals to a creature is enough to destroy it.)

Ashnod, Flesh Mechanist

Deathtouch
Whenever Ashnod, Flesh Mechanist attacks, you may sacrifice another creature. If you do, create a tapped Powerstone token.
{5}, Exile a creature card from your graveyard: Create a tapped 3/3 colorless Zombie artifact creature token.

Haunt of the Dead Marshes

When Haunt of the Dead Marshes enters the battlefield, scry 1.
{2}{B}: Return Haunt of the Dead Marshes from your graveyard to the battlefield tapped. Activate only if you control a legendary creature.

Dirge Bat

Mutate {4}{B}{B} (If you cast this spell for its mutate cost, put it over or under target non-Human creature you own. They mutate into the creature on top plus all abilities from under it.)
Flash
Flying
Whenever this creature mutates, destroy target creature or planeswalker an opponent controls.

Chupacabra Echo

Fathomless descent — When Chupacabra Echo enters the battlefield, target creature an opponent controls gets -X/-X until end of turn, where X is the number of permanent cards in your graveyard.

Ichor Drinker

Lifelink
{B}, Exile Ichor Drinker from your graveyard: Incubate 2. Activate only as a sorcery. (Create an Incubator token with two +1/+1 counters on it and "{2}: Transform this artifact." It transforms into a 0/0 Phyrexian artifact creature.)

Cult Conscript

Cult Conscript enters the battlefield tapped.
{1}{B}: Return Cult Conscript from your graveyard to the battlefield. Activate only if a non-Skeleton creature died under your control this turn.

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature enters the battlefield under your control, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Viconia, Drow Apostate

At the beginning of your upkeep, if there are four or more creature cards in your graveyard, return a creature card at random from your graveyard to your hand.
Choose a Background (You can have a Background as a second commander.)

Shadow of the Enemy

Exile all creature cards from target player's graveyard. You may cast spells from among those cards for as long as they remain exiled, and mana of any type can be spent to cast them.

Dreams of Steel and Oil

Target opponent reveals their hand. You choose an artifact or creature card from it, then choose an artifact or creature card from their graveyard. Exile the chosen cards.

Archfiend's Vessel

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
When Archfiend's Vessel enters the battlefield, if it entered from your graveyard or you cast it from your graveyard, exile it. If you do, create a 5/5 black Demon creature token with flying.

Warehouse Tabby

Whenever an enchantment you control is put into a graveyard from the battlefield, create a 1/1 black Rat creature token with "This creature can't block."
{1}{B}: Warehouse Tabby gains deathtouch until end of turn.

Profane Insight

You draw a card and you lose 1 life. (Then exile this card. You may cast the creature later from exile.)

Foulmire Knight

Foulmire Knight // Profane Insight

Thieves' Guild Enforcer

Flash
Whenever Thieves' Guild Enforcer or another Rogue enters the battlefield under your control, each opponent mills two cards.
As long as an opponent has eight or more cards in their graveyard, Thieves' Guild Enforcer gets +2/+1 and has deathtouch.

Nightmare

Flying (This creature can't be blocked except by creatures with flying or reach.)
Nightmare's power and toughness are each equal to the number of Swamps you control.

Massacre Wurm

When Massacre Wurm enters the battlefield, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Gnawing Vermin

When Gnawing Vermin enters the battlefield, target player mills two cards.
When Gnawing Vermin dies, target creature you don't control gets -1/-1 until end of turn.

Evolved Sleeper

{B}: Evolved Sleeper becomes a Human Cleric with base power and toughness 2/2.
{1}{B}: If Evolved Sleeper is a Cleric, put a deathtouch counter on it and it becomes a Phyrexian Human Cleric with base power and toughness 3/3.
{1}{B}{B}: If Evolved Sleeper is a Phyrexian, put a +1/+1 counter on it, then you draw a card and you lose 1 life.

Deadeye Tracker

{1}{B}, {T}: Exile two target cards from an opponent's graveyard. Deadeye Tracker explores. (Reveal the top card of your library. Put that card into your hand if it's a land. Otherwise, put a +1/+1 counter on this creature, then put the card back or put it into your graveyard.)