Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Licia, Sanguine Tribune

This spell costs {1} less to cast for each 1 life you gained this turn.
First strike, lifelink
Pay 5 life: Put three +1/+1 counters on Licia, Sanguine Tribune. Activate only during your turn and only once each turn.

Punishing Fire

Punishing Fire deals 2 damage to any target.
Whenever an opponent gains life, you may pay {R}. If you do, return Punishing Fire from your graveyard to your hand.

Healing Salve

Choose one —
• Target player gains 3 life.
• Prevent the next 3 damage that would be dealt to any target this turn.

Rest for the Weary

Target player gains 4 life.
Landfall — If you had a land enter the battlefield under your control this turn, that player gains 8 life instead.

Talisman of Conviction

{T}: Add {C}.
{T}: Add {R} or {W}. Talisman of Conviction deals 1 damage to you.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Heliod, Sun-Crowned

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature.
Whenever you gain life, put a +1/+1 counter on target creature or enchantment you control.
{1}{W}: Another target creature gains lifelink until end of turn.

Triskaidekaphobia

At the beginning of your upkeep, choose one —
• Each player with exactly 13 life loses the game, then each player gains 1 life.
• Each player with exactly 13 life loses the game, then each player loses 1 life.

Devour Flesh

Target player sacrifices a creature of their choice, then gains life equal to that creature's toughness.

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

Avenger en-Dal

{2}{W}, {T}, Discard a card: Exile target attacking creature. Its controller gains life equal to its toughness.

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Plague Drone

Flying
Rot Fly — If an opponent would gain life, that player loses that much life instead.

Happily Ever After

When Happily Ever After enters, each player gains 5 life and draws a card.
At the beginning of your upkeep, if there are five colors among permanents you control, there are six or more card types among permanents you control and/or cards in your graveyard, and your life total is greater than or equal to your starting life total, you win the game.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Orcish Medicine

Target creature gains your choice of lifelink or indestructible until end of turn.
Amass Orcs 1. (Put a +1/+1 counter on an Army you control. It's also an Orc. If you don't control an Army, create a 0/0 black Orc Army creature token first.)

Solitude

Flash
Lifelink
When Solitude enters, exile up to one other target creature. That creature's controller gains life equal to its power.
Evoke—Exile a white card from your hand.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Collapsing Borders

Domain — At the beginning of each player's upkeep, that player gains 1 life for each basic land type among lands they control. Then Collapsing Borders deals 3 damage to that player.

Condemn

Put target attacking creature on the bottom of its owner's library. Its controller gains life equal to its toughness.

Oust

Put target creature into its owner's library second from the top. Its controller gains 3 life.

Wedding Ring

When Wedding Ring enters, if it was cast, target opponent creates a token that's a copy of it.
Whenever an opponent who controls an artifact named Wedding Ring draws a card during their turn, you draw a card.
Whenever an opponent who controls an artifact named Wedding Ring gains life during their turn, you gain that much life.

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. Talisman of Indulgence deals 1 damage to you.

Grotesque Mutation

Target creature gets +3/+1 and gains lifelink until end of turn. (Damage dealt by the creature also causes its controller to gain that much life.)

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Spectator Seating

Spectator Seating enters tapped unless you have two or more opponents.
{T}: Add {R} or {W}.

Healing Hands

Armistice

{3}{W}{W}: You draw a card and target opponent gains 3 life.

Plains

Sacred Foundry

({T}: Add {R} or {W}.)
As Sacred Foundry enters, you may pay 2 life. If you don't, it enters tapped.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Congregate

Target player gains 2 life for each creature on the battlefield.

Serra Avatar

Serra Avatar's power and toughness are each equal to your life total.
When Serra Avatar is put into a graveyard from anywhere, shuffle it into its owner's library.

Life Burst

Target player gains 4 life, then gains 4 life for each card named Life Burst in each graveyard.

Luminate Primordial

Vigilance
When Luminate Primordial enters, for each opponent, exile up to one target creature that player controls and that player gains life equal to its power.

Swift Justice

Until end of turn, target creature gets +1/+0 and gains first strike and lifelink.

Ajani, Inspiring Leader

+2: You gain 2 life. Put two +1/+1 counters on up to one target creature.
−3: Exile target creature. Its controller gains 2 life.
−10: Creatures you control gain flying and double strike until end of turn.

Curse of Vitality

Enchant player
Whenever enchanted player is attacked, you gain 2 life. Each opponent attacking that player does the same.

Mountain

Laquatus's Champion

When Laquatus's Champion enters, target player loses 6 life.
When Laquatus's Champion leaves the battlefield, that player gains 6 life.
{B}: Regenerate Laquatus's Champion.

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Blood Crypt

({T}: Add {B} or {R}.)
As Blood Crypt enters, you may pay 2 life. If you don't, it enters tapped.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Savai Triome

({T}: Add {R}, {W}, or {B}.)
Savai Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Blessed Alliance

Escalate {2} (Pay this cost for each mode chosen beyond the first.)
Choose one or more —
• Target player gains 4 life.
• Untap up to two target creatures.
• Target opponent sacrifices an attacking creature of their choice.

Arid Mesa

{T}, Pay 1 life, Sacrifice Arid Mesa: Search your library for a Mountain or Plains card, put it onto the battlefield, then shuffle.

Orzhov Signet

Alabaster Potion

Choose one —
• Target player gains X life.
• Prevent the next X damage that would be dealt to any target this turn.

Sol Ring

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Alchemist's Gift

Target creature gets +1/+1 and gains your choice of deathtouch or lifelink until end of turn. (Any amount of damage a creature with deathtouch deals to a creature is enough to destroy it. Damage dealt by a creature with lifelink also causes its controller to gain that much life.)

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Luxury Suite

Luxury Suite enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Butcher's Glee

Target creature gets +3/+0 and gains lifelink until end of turn. Regenerate it. (Damage dealt by a creature with lifelink also causes its controller to gain that much life.)

Lorehold Command

Choose two —
• Create a 3/2 red and white Spirit creature token.
• Creatures you control get +1/+0 and gain indestructible and haste until end of turn.
• Lorehold Command deals 3 damage to any target. Target player gains 3 life.
• Sacrifice a permanent, then draw two cards.

Strip Mine

{T}: Add {C}.
{T}, Sacrifice Strip Mine: Destroy target land.

Moment of Heroism

Target creature gets +2/+2 and gains lifelink until end of turn. (Damage dealt by the creature also causes its controller to gain that much life.)

Wall of Shards

Defender, flying
Cumulative upkeep—An opponent gains 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Mortal's Ardor

Target creature gets +1/+1 and gains lifelink until end of turn. (Damage dealt by the creature also causes its controller to gain that much life.)

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Illumination

Counter target artifact or enchantment spell. Its controller gains life equal to its mana value.

Mathas, Fiend Seeker

Menace
At the beginning of your end step, put a bounty counter on target creature an opponent controls. For as long as that creature has a bounty counter on it, it has "When this creature dies, each opponent draws a card and gains 2 life."

Boros Signet

Curse of the Forsaken

Enchant player
Whenever a creature attacks enchanted player, its controller gains 1 life.

Soothing Balm

Benevolent Offering

Choose an opponent. You and that player each create three 1/1 white Spirit creature tokens with flying.
Choose an opponent. You gain 2 life for each creature you control and that player gains 2 life for each creature they control.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Aria of Flame

When Aria of Flame enters, each opponent gains 10 life.
Whenever you cast an instant or sorcery spell, put a verse counter on Aria of Flame, then it deals damage equal to the number of verse counters on it to target player or planeswalker.

Reward the Faithful

Any number of target players each gain life equal to the highest mana value among permanents you control.

Lay Down Arms

Exile target creature with mana value less than or equal to the number of Plains you control. Its controller gains 3 life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Bloodstained Mire

{T}, Pay 1 life, Sacrifice Bloodstained Mire: Search your library for a Swamp or Mountain card, put it onto the battlefield, then shuffle.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Krav, the Unredeemed

Partner with Regna, the Redeemer (When this creature enters, target player may put Regna into their hand from their library, then shuffle.)
{B}, Sacrifice X creatures: Target player draws X cards and gains X life. Put X +1/+1 counters on Krav, the Unredeemed.

Rakdos Signet

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Explore the Vastlands

Each player looks at the top five cards of their library and may reveal a land card and/or an instant or sorcery card from among them. Each player puts the cards they revealed this way into their hand and the rest on the bottom of their library in a random order. Each player gains 3 life.

Wandering Archaic

Whenever an opponent casts an instant or sorcery spell, they may pay {2}. If they don't, you may copy that spell. You may choose new targets for the copy.

Wandering Archaic // Explore the Vastlands

Grollub

Whenever Grollub is dealt damage, each opponent gains that much life.

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Sword of Hearth and Home

Equipped creature gets +2/+2 and has protection from green and from white.
Whenever equipped creature deals combat damage to a player, exile up to one target creature you own, then search your library for a basic land card. Put both cards onto the battlefield under your control, then shuffle.
Equip {2}

Swamp

Evra, Halcyon Witness

Lifelink
{4}: Exchange your life total with Evra, Halcyon Witness's power.

Tonic Peddler

{W}, {T}, Discard a card: Target player gains 3 life.

Arbiter of Knollridge

Vigilance
When Arbiter of Knollridge enters, each player's life total becomes the highest life total among all players.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Stinging Study

You draw X cards and you lose X life, where X is the mana value of a commander you own on the battlefield or in the command zone.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Last Breath

Exile target creature with power 2 or less. Its controller gains 4 life.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Arcane Signet

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.