Have

Heartless Hidetsugu

{T}: Heartless Hidetsugu deals damage to each player equal to half that player's life total, rounded down.

Don't Have

Infernal Grasp

Destroy target creature. You lose 2 life.

Terminate

Destroy target creature. It can't be regenerated.

Faithless Looting

Draw two cards, then discard two cards.
Flashback {2}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Sign in Blood

Target player draws two cards and loses 2 life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Rowan's Grim Search

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
If this spell was bargained, look at the top four cards of your library, then put up to two of them back on top of your library in any order and the rest into your graveyard.
You draw two cards and you lose 2 life.