Go for the Throat

Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Heraldic Banner

As this artifact enters, choose a color.
Creatures you control of the chosen color get +1/+0.
{T}: Add one mana of the chosen color.

Leaden Myr

Blackblade Reforged

Equipped creature gets +1/+1 for each land you control.
Equip legendary creature {3}
Equip {7}

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Glistening Sphere

Glistening Sphere enters tapped.
When Glistening Sphere enters, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Swamp

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Suq'Ata Assassin

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
Whenever Suq'Ata Assassin attacks and isn't blocked, defending player gets a poison counter. (A player with ten or more poison counters loses the game.)

Barren Moor

Barren Moor enters tapped.
{T}: Add {B}.
Cycling {B} ({B}, Discard this card: Draw a card.)

Skithiryx, the Blight Dragon

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx, the Blight Dragon gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

Darksteel Plate

Indestructible
Equipped creature has indestructible.
Equip {2}

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Endless Scream

Enchant creature
Endless Scream enters with X scream counters on it.
Enchanted creature gets +1/+0 for each scream counter on Endless Scream.

Strata Scythe

Imprint — When Strata Scythe enters, search your library for a land card, exile it, then shuffle.
Equipped creature gets +1/+1 for each land on the battlefield with the same name as the exiled card.
Equip {3}

Whisper of the Dross

Target creature gets -1/-1 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

O-Naginata

O-Naginata can be attached only to a creature with power 3 or greater.
Equipped creature gets +3/+0 and has trample.
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Throne of Geth

{T}, Sacrifice an artifact: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Pestilent Syphoner

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Skeletal Scrying

As an additional cost to cast this spell, exile X cards from your graveyard.
You draw X cards and you lose X life.

Languish

All creatures get -4/-4 until end of turn.

Nightmare Lash

Equipped creature gets +1/+1 for each Swamp you control.
Equip—Pay 3 life. (Pay 3 life: Attach to target creature you control. Equip only as a sorcery. This card enters unattached and stays on the battlefield if the creature leaves.)

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Inkmoth Nexus

{T}: Add {C}.
{1}: Inkmoth Nexus becomes a 1/1 Phyrexian Blinkmoth artifact creature with flying and infect until end of turn. It's still a land. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Phyrexian Vatmother

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
At the beginning of your upkeep, you get a poison counter.

Glaring Spotlight

Creatures your opponents control with hexproof can be the targets of spells and abilities you control as though they didn't have hexproof.
{3}, Sacrifice Glaring Spotlight: Creatures you control gain hexproof until end of turn and can't be blocked this turn.

Blackcleave Goblin

Haste
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Opal Palace

{T}: Add {C}.
{1}, {T}: Add one mana of any color in your commander's color identity. If you spend this mana to cast your commander, it enters with a number of additional +1/+1 counters on it equal to the number of times it's been cast from the command zone this game.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Mask of Griselbrand

Equipped creature has flying and lifelink.
Whenever equipped creature dies, you may pay X life, where X is its power. If you do, draw X cards.
Equip {3}

Witch's Cottage

({T}: Add {B}.)
Witch's Cottage enters tapped unless you control three or more other Swamps.
When Witch's Cottage enters untapped, you may put target creature card from your graveyard on top of your library.

Sceptre of Eternal Glory

{T}: Add one mana of any color.
{T}: Add three mana of any one color. Activate only if you control three or more lands with the same name.

Loxodon Warhammer

Equipped creature gets +3/+0 and has trample and lifelink.
Equip {3}

Feed the Infection

You draw three cards and you lose 3 life.
Corrupted — Each opponent who has three or more poison counters loses 3 life.

Mutilate

All creatures get -1/-1 until end of turn for each Swamp you control.

Ambition's Cost

You draw three cards and you lose 3 life.

Buried Ruin

{T}: Add {C}.
{2}, {T}, Sacrifice Buried Ruin: Return target artifact card from your graveyard to your hand.

Sword of Vengeance

Equipped creature gets +2/+0 and has first strike, vigilance, trample, and haste.
Equip {3}

Bad Moon

Nettlecyst

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +1/+1 for each artifact and/or enchantment you control.
Equip {2}

Geth's Summons

Return up to one target creature card from your graveyard to the battlefield.
Corrupted — For each opponent who has three or more poison counters as you cast this spell, put up to one target creature card from that player's graveyard onto the battlefield under your control.

Infernal Grasp

Destroy target creature. You lose 2 life.

Plague Stinger

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Decimator Web

{4}, {T}: Target opponent loses 2 life, gets a poison counter, then mills six cards.

Hand of the Praetors

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Other creatures you control with infect get +1/+1.
Whenever you cast a creature spell with infect, target player gets a poison counter.

Key to the City

{T}, Discard a card: Up to one target creature can't be blocked this turn.
Whenever Key to the City becomes untapped, you may pay {2}. If you do, draw a card.

Prowler's Helm

Equipped creature can't be blocked except by Walls.
Equip {2}

Vat Emergence

Put target creature card from a graveyard onto the battlefield under your control. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Gulping Scraptrap

When Gulping Scraptrap enters or dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Commander's Plate

Equipped creature gets +3/+3 and has protection from each color that's not in your commander's color identity.
Equip commander {3}
Equip {5}

Rush of Vitality

Target creature gets +1/+0 and gains lifelink and indestructible until end of turn. (Damage dealt by that creature also causes its controller to gain that much life, and it can't be destroyed by damage or effects that say "destroy.")

Bloodcurdling Scream

Target creature gets +X/+0 until end of turn.

Caress of Phyrexia

Target player draws three cards, loses 3 life, and gets three poison counters.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Charcoal Diamond

Charcoal Diamond enters tapped.
{T}: Add {B}.

Plague Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{T}: Add {C}.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Mithril Coat

Flash
Indestructible
When Mithril Coat enters, attach it to target legendary creature you control.
Equipped creature has indestructible.
Equip {3}

Whispersilk Cloak

Equipped creature can't be blocked and has shroud. (It can't be the target of spells or abilities.)
Equip {2}

Magus of the Coffers

{2}, {T}: Add {B} for each Swamp you control.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

War Room

{T}: Add {C}.
{3}, {T}, Pay life equal to the number of colors in your commanders' color identity: Draw a card.

Reaper of Sheoldred

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever a source deals damage to Reaper of Sheoldred, that source's controller gets a poison counter.

Chittering Skitterling

Corrupted — Sacrifice an artifact or creature: Draw a card. Activate only if an opponent has three or more poison counters and only once each turn.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Greed

Relic Putrescence

Enchant artifact
Whenever enchanted artifact becomes tapped, its controller gets a poison counter.

Fireshrieker

Equipped creature has double strike. (It deals both first-strike and regular combat damage.)
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Wedding Invitation

When Wedding Invitation enters, draw a card.
{T}, Sacrifice Wedding Invitation: Target creature can't be blocked this turn. If it's a Vampire, it also gains lifelink until end of turn.

Force of Despair

If it's not your turn, you may exile a black card from your hand rather than pay this spell's mana cost.
Destroy all creatures that entered this turn.

Dauthi Trapper

{T}: Target creature gains shadow until end of turn. (It can block or be blocked by only creatures with shadow.)

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap Staff of Compleation.

Sewers of Estark

Choose target creature. If it's attacking, it can't be blocked this turn. If it's blocking, prevent all combat damage that would be dealt this combat by it and each creature it's blocking.

Anoint with Affliction

Exile target creature if it has mana value 3 or less.
Corrupted — Exile that creature instead if its controller has three or more poison counters.

Dread Presence

Whenever a Swamp you control enters, choose one —
• You draw a card and you lose 1 life.
• Dread Presence deals 2 damage to any target and you gain 2 life.

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters, each player gets a poison counter.

Jet Medallion

Black spells you cast cost {1} less to cast.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Drannith Ruins

{T}: Add {C}.
{2}, {T}: Put two +1/+1 counters on target non-Human creature that entered this turn.

Virulent Wound

Put a -1/-1 counter on target creature. When that creature dies this turn, its controller gets a poison counter.

Cathedral of War

Cathedral of War enters tapped.
Exalted (Whenever a creature you control attacks alone, that creature gets +1/+1 until end of turn.)
{T}: Add {C}.

Kinzu of the Bleak Coven

Flying
Whenever another nontoken creature you control dies, you may pay 2 life and exile it. If you do, create a token that's a copy of that creature, except it's 1/1 and has toxic 1. (Players dealt combat damage by it also get a poison counter.)

Vector Asp

{B}: Vector Asp gains infect until end of turn. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Soul Shatter

Each opponent sacrifices a creature or planeswalker with the highest mana value among creatures and planeswalkers they control.

Necroskitter

Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever a creature an opponent controls with a -1/-1 counter on it dies, you may return that card to the battlefield under your control.

Unspeakable Symbol

Pay 3 life: Put a +1/+1 counter on target creature.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Helm of the Host

At the beginning of combat on your turn, create a token that's a copy of equipped creature, except the token isn't legendary. That token gains haste.
Equip {5}

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Shizo, Death's Storehouse

{T}: Add {B}.
{B}, {T}: Target legendary creature gains fear until end of turn. (It can't be blocked except by artifact creatures and/or black creatures.)

Inquisitor's Flail

If equipped creature would deal combat damage, it deals double that damage instead.
If another creature would deal combat damage to equipped creature, it deals double that damage to equipped creature instead.
Equip {2}

Dauthi Embrace

{B}{B}: Target creature gains shadow until end of turn. (It can block or be blocked by only creatures with shadow.)

Phyrexian Crusader

First strike, protection from red and from white
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)