Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Marble Diamond

Marble Diamond enters tapped.
{T}: Add {W}.

Riot Control

You gain 1 life for each creature your opponents control. Prevent all damage that would be dealt to you this turn.

Greed

Grand Abolisher

During your turn, your opponents can't cast spells or activate abilities of artifacts, creatures, or enchantments.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Secluded Steppe

Secluded Steppe enters tapped.
{T}: Add {W}.
Cycling {W} ({W}, Discard this card: Draw a card.)

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Swamp

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Fracture

Destroy target artifact, enchantment, or planeswalker.

Daxos, Blessed by the Sun

Daxos's toughness is equal to your devotion to white. (Each {W} in the mana costs of permanents you control counts toward your devotion to white.)
Whenever another creature you control enters or dies, you gain 1 life.

Barren Moor

Barren Moor enters tapped.
{T}: Add {B}.
Cycling {B} ({B}, Discard this card: Draw a card.)

Sigarda's Splendor

As Sigarda's Splendor enters, note your life total.
At the beginning of your upkeep, draw a card if your life total is greater than or equal to the last noted life total for Sigarda's Splendor. Then note your life total.
Whenever you cast a white spell, you gain 1 life.

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Markov Purifier

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay {2}. If you do, draw a card.

Seraph Sanctuary

When Seraph Sanctuary enters, you gain 1 life.
Whenever an Angel you control enters, you gain 1 life.
{T}: Add {C}.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Cleric Class

(Gain the next level as a sorcery to add its ability.)
If you would gain life, you gain that much life plus 1 instead.
{3}{W}: Level 2
Whenever you gain life, put a +1/+1 counter on target creature you control.
{4}{W}: Level 3
When this Class becomes level 3, return target creature card from your graveyard to the battlefield. You gain life equal to that creature's toughness.

Pristine Talisman

Infernal Grasp

Destroy target creature. You lose 2 life.

Invoke the Divine

Destroy target artifact or enchantment. You gain 4 life.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Despark

Exile target permanent with mana value 4 or greater.

Archivist of Oghma

Flash
Whenever an opponent searches their library, you gain 1 life and draw a card.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Charcoal Diamond

Charcoal Diamond enters tapped.
{T}: Add {B}.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Sunscorch Regent

Flying
Whenever an opponent casts a spell, put a +1/+1 counter on Sunscorch Regent and you gain 1 life.

Tithe Drinker

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Ancient Craving

You draw three cards and you lose 3 life.

Sign in Blood

Target player draws two cards and loses 2 life.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Scoured Barrens

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {W} or {B}.

Plains

Murder

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Soul Warden

Whenever another creature enters, you gain 1 life.

Rug of Smothering

Flying
Whenever a player casts a spell, they lose 1 life for each spell they've cast this turn.

Revitalize

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Orzhov Signet

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Angel of Vitality

Flying
If you would gain life, you gain that much life plus 1 instead.
This creature gets +2/+2 as long as you have 25 or more life.

Mortify

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Sol Ring

Kunoros, Hound of Athreos

Vigilance, menace, lifelink
Creature cards in graveyards can't enter the battlefield.
Players can't cast spells from graveyards.

Ambition's Cost

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Kaya, Intangible Slayer

Hexproof
+2: Each opponent loses 3 life and you gain 3 life.
0: You draw two cards. Then each opponent may scry 1.
−3: Exile target creature or enchantment. If it wasn't an Aura, create a token that's a copy of it, except it's a 1/1 white Spirit creature with flying in addition to its other types.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Liesa, Shroud of Dusk

Rather than pay {2} for each previous time you've cast this spell from the command zone this game, pay 2 life that many times.
Flying, lifelink
Whenever a player casts a spell, they lose 2 life.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Utter End

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Kabira Crossroads

Kabira Crossroads enters tapped.
When Kabira Crossroads enters, you gain 2 life.
{T}: Add {W}.

Drana and Linvala

Flying, vigilance
Activated abilities of creatures your opponents control can't be activated.
Drana and Linvala has all activated abilities of all creatures your opponents control. You may spend mana as though it were mana of any color to activate those abilities.

Radiant Fountain

When Radiant Fountain enters, you gain 2 life.
{T}: Add {C}.

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.