Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Child of Alara

Trample
When Child of Alara dies, destroy all nonland permanents. They can't be regenerated.

Mountain

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Planar Cleansing

Desolation Giant

Kicker {W}{W} (You may pay an additional {W}{W} as you cast this spell.)
When Desolation Giant enters, destroy all other creatures you control. If it was kicked, destroy all other creatures instead.

Forest

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Orzhov Signet

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Klothys, God of Destiny

Indestructible
As long as your devotion to red and green is less than seven, Klothys isn't a creature.
At the beginning of your first main phase, exile target card from a graveyard. If it was a land card, add {R} or {G}. Otherwise, you gain 2 life and Klothys deals 2 damage to each opponent.

Exterminatus

Nonland permanents your opponents control lose indestructible until end of turn.
Destroy all nonland permanents.

Settle the Wreckage

Exile all attacking creatures target player controls. That player may search their library for that many basic land cards, put those cards onto the battlefield tapped, then shuffle.

Dimir Signet

Athreos, Shroud-Veiled

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
At the beginning of your end step, put a coin counter on another target creature.
Whenever a creature with a coin counter on it dies or is put into exile, return that card to the battlefield under your control.

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

Ghostly Prison

Swamp

Circuitous Route

Search your library for up to two basic land cards and/or Gate cards, put them onto the battlefield tapped, then shuffle.

Day of Judgment

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Prismatic Omen

Lands you control are every basic land type in addition to their other types.

Boros Signet

Wrath of God

Destroy all creatures. They can't be regenerated.

Sylvan Scrying

Search your library for a land card, reveal it, put it into your hand, then shuffle.

Terminus

Put all creatures on the bottom of their owners' libraries.
Miracle {W} (You may cast this card for its miracle cost when you draw it if it's the first card you drew this turn.)

Akroma's Vengeance

Destroy all artifacts, creatures, and enchantments.
Cycling {3} ({3}, Discard this card: Draw a card.)

Damnation

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Plains

Golgari Signet

Jokulhaups

Destroy all artifacts, creatures, and lands. They can't be regenerated.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Talisman of Conviction

{T}: Add {C}.
{T}: Add {R} or {W}. Talisman of Conviction deals 1 damage to you.

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Magus of the Disk

Magus of the Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Doomskar

Destroy all creatures.
Foretell {1}{W}{W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Kodama's Reach

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Talisman of Creativity

{T}: Add {C}.
{T}: Add {U} or {R}. Talisman of Creativity deals 1 damage to you.

Talisman of Curiosity

{T}: Add {C}.
{T}: Add {G} or {U}. Talisman of Curiosity deals 1 damage to you.

Avacyn, Angel of Hope

Flying, vigilance, indestructible
Other permanents you control have indestructible.

Rampant Growth

Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Keranos, God of Storms

Indestructible
As long as your devotion to blue and red is less than seven, Keranos isn't a creature.
Reveal the first card you draw on each of your turns. Whenever you reveal a land card this way, draw a card. Whenever you reveal a nonland card this way, Keranos deals 3 damage to any target.

End Hostilities

Destroy all creatures and all permanents attached to creatures.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Azorius Signet

Athreos, God of Passage

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
Whenever another creature you own dies, return it to your hand unless target opponent pays 3 life.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. Talisman of Indulgence deals 1 damage to you.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Zetalpa, Primal Dawn

Flying, double strike, vigilance, trample, indestructible

Farseek

Search your library for a Plains, Island, Swamp, or Mountain card, put it onto the battlefield tapped, then shuffle.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Gruul Signet

Izzet Signet

Rakdos Signet

Simic Signet

Talisman of Progress

{T}: Add {C}.
{T}: Add {W} or {U}. Talisman of Progress deals 1 damage to you.

Island

Talisman of Unity

{T}: Add {C}.
{T}: Add {G} or {W}. Talisman of Unity deals 1 damage to you.

Talisman of Resilience

{T}: Add {C}.
{T}: Add {B} or {G}. Talisman of Resilience deals 1 damage to you.

Planar Collapse

At the beginning of your upkeep, if there are four or more creatures on the battlefield, sacrifice Planar Collapse and destroy all creatures. They can't be regenerated.

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature of their choice.

Talisman of Impulse

{T}: Add {C}.
{T}: Add {R} or {G}. Talisman of Impulse deals 1 damage to you.

Selesnya Signet

Open the Gates

Search your library for a basic land card or Gate card, reveal it, put it into your hand, then shuffle.

Back to Nature

Ruinous Ultimatum

Destroy all nonland permanents your opponents control.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")