Have

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Getting

Ashiok, Dream Render

Spells and abilities your opponents control can't cause their controller to search their library.
−1: Target player mills four cards. Then exile each opponent's graveyard.

Don't Have

Virulent Wound

Put a -1/-1 counter on target creature. When that creature dies this turn, its controller gets a poison counter.

Ponder

Look at the top three cards of your library, then put them back in any order. You may shuffle.
Draw a card.

Day's Undoing

Each player shuffles their hand and graveyard into their library, then draws seven cards. If it's your turn, end the turn. (Exile all spells and abilities from the stack, including this card. Discard down to your maximum hand size. Damage wears off, and "this turn" and "until end of turn" effects end.)

Shark Typhoon

Whenever you cast a noncreature spell, create an X/X blue Shark creature token with flying, where X is that spell's mana value.
Cycling {X}{1}{U} ({X}{1}{U}, Discard this card: Draw a card.)
When you cycle Shark Typhoon, create an X/X blue Shark creature token with flying.

Whisper of the Dross

Target creature gets -1/-1 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Strategic Planning

Look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.

Murmuring Mystic

Whenever you cast an instant or sorcery spell, create a 1/1 blue Bird Illusion creature token with flying.

Mystic Sanctuary

({T}: Add {U}.)
Mystic Sanctuary enters tapped unless you control three or more other Islands.
When Mystic Sanctuary enters untapped, you may put target instant or sorcery card from your graveyard on top of your library.

Aether Gale

Return six target nonland permanents to their owners' hands.

Temple of Deceit

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {U} or {B}.

Bring the Ending

Counter target spell unless its controller pays {2}.
Corrupted — Counter that spell instead if its controller has three or more poison counters.

Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Bilious Skulldweller

Deathtouch
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Teferi, Master of Time

You may activate loyalty abilities of Teferi, Master of Time on any player's turn any time you could cast an instant.
+1: Draw a card, then discard a card.
−3: Target creature you don't control phases out. (Treat it and anything attached to it as though they don't exist until its controller's next turn.)
−10: Take two extra turns after this one.

Swamp

Borne Upon a Wind

You may cast spells this turn as though they had flash.
Draw a card.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.

Spread the Sickness

Destroy target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Blightbelly Rat

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Blightbelly Rat dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters, each player gets a poison counter.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Solve the Equation

Search your library for an instant or sorcery card, reveal it, put it into your hand, then shuffle.

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Preordain

Scry 2, then draw a card. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Blighted Agent

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Blighted Agent can't be blocked.

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

Snap

Return target creature to its owner's hand. Untap up to two lands.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Leyline of Anticipation

If Leyline of Anticipation is in your opening hand, you may begin the game with it on the battlefield.
You may cast spells as though they had flash.

Mindsplice Apparatus

Flash
At the beginning of your upkeep, put an oil counter on Mindsplice Apparatus.
Instant and sorcery spells you cast cost {1} less to cast for each oil counter on Mindsplice Apparatus.

Dimir Signet

Steady Progress

Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Draw a card.

Scry 1. (Look at the top card of your library. You may put that card on the bottom.)
Draw a card.

Plague Stinger

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Plague Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{T}: Add {C}.

Rewind

Counter target spell. Untap up to four lands.

Consuming Tide

Each player chooses a nonland permanent they control. Return all nonland permanents not chosen this way to their owners' hands. Then you draw a card for each opponent who has more cards in their hand than you.

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Talrand, Sky Summoner

Whenever you cast an instant or sorcery spell, create a 2/2 blue Drake creature token with flying.

Gale, Waterdeep Prodigy

Whenever you cast an instant or sorcery spell from your hand, you may cast up to one target card of the other type from your graveyard. If a spell cast from your graveyard this way would be put into your graveyard, exile it instead.
Choose a Background (You can have a Background as a second commander.)

Serum Visions

Pestilent Syphoner

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Counterspell

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Inexorable Tide

Whenever you cast a spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Flux Channeler

Whenever you cast a noncreature spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Drown in Ichor

Target creature gets -4/-4 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Chrome Host Seedshark

Flying
Whenever you cast a noncreature spell, incubate X, where X is that spell's mana value. (Create an Incubator token with X +1/+1 counters on it and "{2}: Transform this artifact." It transforms into a 0/0 Phyrexian artifact creature.)

Hostile Negotiations

Exile the top three cards of your library in a face-down pile, then exile the top three cards of your library in another face-down pile. Look at the cards in each pile, then turn a pile of your choice face up. An opponent chooses one of those piles. Put that pile into your hand and the other into your graveyard. You lose 3 life.

Reject Imperfection

Counter target spell. If that spell's mana value was 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Windfall

Each player discards their hand, then draws cards equal to the greatest number of cards a player discarded this way.

Skithiryx, the Blight Dragon

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx, the Blight Dragon gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

Narset's Reversal

Copy target instant or sorcery spell, then return it to its owner's hand. You may choose new targets for the copy.

Tekuthal, Inquiry Dominus

Flying
If you would proliferate, proliferate twice instead.
{1}{U/P}{U/P}, Remove three counters from among other artifacts, creatures, and planeswalkers you control: Put an indestructible counter on Tekuthal, Inquiry Dominus. ({U/P} can be paid with either {U} or 2 life.)

Reaper of Sheoldred

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever a source deals damage to Reaper of Sheoldred, that source's controller gets a poison counter.

Archmage Emeritus

Magecraft — Whenever you cast or copy an instant or sorcery spell, draw a card.

Anoint with Affliction

Exile target creature if it has mana value 3 or less.
Corrupted — Exile that creature instead if its controller has three or more poison counters.

Mystical Tutor

Search your library for an instant or sorcery card, reveal it, then shuffle and put that card on top.

Viral Drake

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{3}{U}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Distorted Curiosity

Corrupted — This spell costs {2} less to cast if an opponent has three or more poison counters.
Draw two cards.

Scion of Halaster

Commander creatures you own have "The first time you would draw a card each turn, instead look at the top two cards of your library. Put one of them into your graveyard and the other back on top of your library. Then draw a card."

Ichorclaw Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever Ichorclaw Myr becomes blocked, it gets +2/+2 until end of turn.

Experimental Augury

Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Devastation Tide

Return all nonland permanents to their owners' hands.
Miracle {1}{U} (You may cast this card for its miracle cost when you draw it if it's the first card you drew this turn.)

Thrummingbird

Flying
Whenever Thrummingbird deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Contentious Plan

Negate

God-Eternal Kefnet

Flying
You may reveal the first card you draw each turn as you draw it. Whenever you reveal an instant or sorcery card this way, copy that card and you may cast the copy. That copy costs {2} less to cast.
When God-Eternal Kefnet dies or is put into exile from the battlefield, you may put it into its owner's library third from the top.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Venser, Corpse Puppet

Lifelink, toxic 1
Whenever you proliferate, choose one —
• If you don't control a creature named The Hollow Sentinel, create The Hollow Sentinel, a legendary 3/3 colorless Phyrexian Golem artifact creature token.
• Target artifact creature you control gains flying and lifelink until end of turn.

Glistening Sphere

Glistening Sphere enters tapped.
When Glistening Sphere enters, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Will Kenrith

+2: Until your next turn, up to two target creatures each have base power and toughness 0/3 and lose all abilities.
−2: Target player draws two cards. Until your next turn, instant, sorcery, and planeswalker spells that player casts cost {2} less to cast.
−8: Target player gets an emblem with "Whenever you cast an instant or sorcery spell, copy it. You may choose new targets for the copy."
Partner with Rowan Kenrith
Will Kenrith can be your commander.

Voidwing Hybrid

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When you proliferate, return Voidwing Hybrid from your graveyard to your hand.

Storm of Saruman

Ward {3}
Whenever you cast your second spell each turn, copy it, except the copy isn't legendary. You may choose new targets for the copy. (A copy of a permanent spell becomes a token.)

Vat Emergence

Put target creature card from a graveyard onto the battlefield under your control. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Geth's Summons

Return up to one target creature card from your graveyard to the battlefield.
Corrupted — For each opponent who has three or more poison counters as you cast this spell, put up to one target creature card from that player's graveyard onto the battlefield under your control.

Hero's Downfall

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Path of Ancestry

Path of Ancestry enters tapped.
{T}: Add one mana of any color in your commander's color identity. When that mana is spent to cast a creature spell that shares a creature type with your commander, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Frantic Search

Draw two cards, then discard two cards. Untap up to three lands.

Mercurial Spelldancer

Mercurial Spelldancer can't be blocked.
Whenever you cast a noncreature spell, put an oil counter on Mercurial Spelldancer.
Whenever Mercurial Spelldancer deals combat damage to a player, you may remove two oil counters from it. If you do, when you next cast an instant or sorcery spell this turn, copy that spell. You may choose new targets for the copy.

Ledger Shredder

Flying
Whenever a player casts their second spell each turn, Ledger Shredder connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)

Serum Snare

Return target nonland permanent to its owner's hand. If that permanent had mana value 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Consider

Surveil 1. (Look at the top card of your library. You may put it into your graveyard.)
Draw a card.

Command Tower

Island

See the Truth

Look at the top three cards of your library. Put one of those cards into your hand and the rest on the bottom of your library in any order. If this spell was cast from anywhere other than your hand, put each of those cards into your hand instead.

Done

Tap up to two target creatures. Those creatures don't untap during their controller's next untap step.

Said

Return target instant or sorcery card from your graveyard to your hand.

Said // Done

Archaeomancer

When Archaeomancer enters, return target instant or sorcery card from your graveyard to your hand.

Phyresis Outbreak

Each opponent gets a poison counter. Then each creature your opponents control gets -1/-1 until end of turn for each poison counter its controller has.