Thrill of Possibility

As an additional cost to cast this spell, discard a card.
Draw two cards.

Faerie Fencing

Target creature gets -X/-X until end of turn. That creature gets an additional -3/-3 until end of turn if you controlled a Faerie as you cast this spell.

Braids's Frightful Return

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — You may sacrifice a creature. If you do, each opponent discards a card.
II — Return target creature card from your graveyard to your hand.
III — Target opponent may sacrifice a nonland, nontoken permanent of their choice. If they don't, they lose 2 life and you draw a card.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Poxwalkers

Deathtouch
Curse of the Walking Pox — Whenever you cast a spell from anywhere other than your hand, return Poxwalkers from your graveyard to the battlefield tapped.

Chain Lightning

Chain Lightning deals 3 damage to any target. Then that player or that permanent's controller may pay {R}{R}. If the player does, they may copy this spell and may choose a new target for that copy.

Offer Immortality

Target creature gains deathtouch and indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Lightning Axe

As an additional cost to cast this spell, discard a card or pay {5}.
Lightning Axe deals 5 damage to target creature.

Exquisite Firecraft

Exquisite Firecraft deals 4 damage to any target.
Spell mastery — If there are two or more instant and/or sorcery cards in your graveyard, this spell can't be countered.

Great Unclean One

Reverberating Summons — At the beginning of your end step, each opponent loses 2 life. Then for each opponent who has less life than you, create a 1/3 black Demon creature token named Plaguebearer of Nurgle.

Toxic Abomination

When Toxic Abomination enters, you lose 2 life.

Patriar's Seal

{T}: Add one mana of any color.
{1}, {T}: Untap target legendary creature you control.

Guttersnipe

Whenever you cast an instant or sorcery spell, this creature deals 2 damage to each opponent.

Fiery Inscription

When Fiery Inscription enters, the Ring tempts you.
Whenever you cast an instant or sorcery spell, Fiery Inscription deals 2 damage to each opponent.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Vat of Rebirth

Whenever another artifact or creature you control is put into a graveyard from the battlefield, put an oil counter on Vat of Rebirth.
{2}{B}, {T}, Remove four oil counters from Vat of Rebirth: Return target creature card from your graveyard to the battlefield. Activate only as a sorcery.

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Electrickery

Electrickery deals 1 damage to target creature you don't control.
Overload {1}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Magic Missile

This spell can't be countered.
Magic Missile deals 3 damage divided as you choose among one, two, or three targets.

Stonesplitter Bolt

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
Stonesplitter Bolt deals X damage to target creature or planeswalker. If this spell was bargained, it deals twice X damage to that permanent instead.

Rankle's Prank

Choose one or more —
• Each player discards two cards.
• Each player loses 4 life.
• Each player sacrifices two creatures of their choice.

Lightning Bolt

Lightning Bolt deals 3 damage to any target.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Wild Guess

Rowan, Scion of War

Menace
{T}: Spells you cast this turn that are black and/or red cost {X} less to cast, where X is the amount of life you lost this turn. Activate only as a sorcery.

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Plague Drone

Flying
Rot Fly — If an opponent would gain life, that player loses that much life instead.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Eriette's Tempting Apple

When Eriette's Tempting Apple enters, gain control of target creature until end of turn. Untap that creature. It gains haste until end of turn.
{2}, {T}, Sacrifice Eriette's Tempting Apple: You gain 3 life.
{2}, {T}, Sacrifice Eriette's Tempting Apple: Target opponent loses 3 life.

Impact Tremors

Whenever a creature you control enters, this enchantment deals 1 damage to each opponent.

Vindictive Flamestoker

Whenever you cast a noncreature spell, put an oil counter on Vindictive Flamestoker.
{6}{R}, Sacrifice Vindictive Flamestoker: Discard your hand, then draw four cards. This ability costs {1} less to activate for each oil counter on Vindictive Flamestoker.

Terror

Destroy target nonartifact, nonblack creature. It can't be regenerated.

Crystal Grotto

When Crystal Grotto enters, scry 1.
{T}: Add {C}.
{1}, {T}: Add one mana of any color.

Black Sun's Twilight

Up to one target creature gets -X/-X until end of turn. If X is 5 or more, return a creature card with mana value X or less from your graveyard to the battlefield tapped.

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap Staff of Compleation.

Sting, the Glinting Dagger

Equipped creature gets +1/+1 and has haste.
At the beginning of each combat, untap equipped creature.
Equipped creature has first strike as long as it's blocking or blocked by a Goblin or Orc.
Equip {2}

Burn Together

Target creature you control deals damage equal to its power to any other target. Then sacrifice it.

Callous Sell-Sword

Callous Sell-Sword enters with a +1/+1 counter on it for each creature that died under your control this turn.

Callous Sell-Sword // Burn Together

Mountain

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Myr Convert

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
{T}, Pay 2 life: Add one mana of any color.

Magus of the Wheel

{1}{R}, {T}, Sacrifice Magus of the Wheel: Each player discards their hand, then draws seven cards.

Vraan, Executioner Thane

Whenever one or more other creatures you control die, each opponent loses 2 life and you gain 2 life. This ability triggers only once each turn.

Phyrexian Obliterator

Trample
Whenever a source deals damage to Phyrexian Obliterator, that source's controller sacrifices that many permanents of their choice.

Cloudkill

All creatures get -X/-X until end of turn, where X is the greatest mana value of a commander you own on the battlefield or in the command zone.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Ob Nixilis Reignited

+1: You draw a card and you lose 1 life.
−3: Destroy target creature.
−8: Target opponent gets an emblem with "Whenever a player draws a card, you lose 2 life."

Swamp

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Mortarion, Daemon Primarch

Flying
Primarch of the Death Guard — At the beginning of your end step, you may pay {X}. If you do, create X 2/2 black Astartes Warrior creature tokens with menace. X can't be greater than the amount of life you lost this turn.

Pact Weapon

As long as Pact Weapon is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Ob Nixilis, Unshackled

Flying, trample
Whenever an opponent searches their library, that player sacrifices a creature of their choice and loses 10 life.
Whenever another creature dies, put a +1/+1 counter on Ob Nixilis, Unshackled.

Greed

Sign in Blood

Target player draws two cards and loses 2 life.

Red Sun's Twilight

Destroy up to X target artifacts. If X is 5 or more, for each artifact destroyed this way, create a token that's a copy of it. Those tokens gain haste. Exile them at the beginning of the next end step.

Palace Siege

As Palace Siege enters, choose Khans or Dragons.
• Khans — At the beginning of your upkeep, return target creature card from your graveyard to your hand.
• Dragons — At the beginning of your upkeep, each opponent loses 2 life and you gain 2 life.

Dark Tutelage

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Lord Skitter's Blessing

When Lord Skitter's Blessing enters, create a Wicked Role token attached to target creature you control. (Enchanted creature gets +1/+1. When this Aura is put into a graveyard, each opponent loses 1 life.)
At the beginning of your draw step, if you control an enchanted creature, you lose 1 life and you draw an additional card.

Shock

Solphim, Mayhem Dominus

If a source you control would deal noncombat damage to an opponent or a permanent an opponent controls, it deals double that damage to that player or permanent instead.
{1}{R/P}{R/P}, Discard two cards: Put an indestructible counter on Solphim, Mayhem Dominus. ({R/P} can be paid with either {R} or 2 life.)

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent of their choice that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Expensive Taste

Exile the top two cards of target opponent's library face down. You may look at and play those cards for as long as they remain exiled.

Decadent Dragon

Flying, trample
Whenever Decadent Dragon attacks, create a Treasure token.

Decadent Dragon // Expensive Taste

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.

Parasitic Impetus

Enchant creature
Enchanted creature gets +2/+2 and is goaded. (It attacks each combat if able and attacks a player other than you if able.)
Whenever enchanted creature attacks, its controller loses 2 life and you gain 2 life.