Have

Defiler of Instinct

First strike
As an additional cost to cast red permanent spells, you may pay 2 life. Those spells cost {R} less to cast if you paid life this way. This effect reduces only the amount of red mana you pay.
Whenever you cast a red permanent spell, Defiler of Instinct deals 1 damage to any target.

Sol Ring

Frantic Firebolt

Frantic Firebolt deals X damage to target creature, where X is 2 plus the number of cards in your graveyard that are instant cards, sorcery cards, and/or have an Adventure.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

Searstep Pathway

Blightstep Pathway

Blightstep Pathway // Searstep Pathway

Dark Tutelage

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Sulfurous Springs

{T}: Add {C}.
{T}: Add {B} or {R}. Sulfurous Springs deals 1 damage to you.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Plunge into Darkness

Choose one —
• Sacrifice any number of creatures. You gain 3 life for each creature sacrificed this way.
• Pay any amount of life, then look at that many cards from the top of your library. Put one of those cards into your hand and exile the rest.
Entwine {B} (Choose both if you pay the entwine cost.)

Pyroblast

Choose one —
• Counter target spell if it's blue.
• Destroy target permanent if it's blue.

Chandra, Hope's Beacon

Whenever you cast an instant or sorcery spell, copy it. You may choose new targets for the copy. This ability triggers only once each turn.
+2: Add two mana in any combination of colors.
+1: Exile the top five cards of your library. Until the end of your next turn, you may cast an instant or sorcery spell from among those exiled cards.
−X: Chandra, Hope's Beacon deals X damage to each of up to two targets.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Unspeakable Symbol

Pay 3 life: Put a +1/+1 counter on target creature.

Paradise Plume

As Paradise Plume enters, choose a color.
Whenever a player casts a spell of the chosen color, you may gain 1 life.
{T}: Add one mana of the chosen color.

Ambition's Cost

You draw three cards and you lose 3 life.

Ad Nauseam

Reveal the top card of your library and put that card into your hand. You lose life equal to its mana value. You may repeat this process any number of times.

Getting

Comet Storm

Multikicker {1} (You may pay an additional {1} any number of times as you cast this spell.)
Choose any target, then choose another target for each time this spell was kicked. Comet Storm deals X damage to each of them.

Blackcleave Cliffs

Blackcleave Cliffs enters tapped unless you control two or fewer other lands.
{T}: Add {B} or {R}.

Kill! Maim! Burn!

Choose one or more —
• Destroy target artifact.
• Destroy target creature.
• Kill! Maim! Burn! deals 3 damage to target player.

Keen Duelist

At the beginning of your upkeep, you and target opponent each reveal the top card of your library. You each lose life equal to the mana value of the card revealed by the other player. You each put the card you revealed into your hand.

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Rakdos, Lord of Riots

You can't cast Rakdos, Lord of Riots unless an opponent lost life this turn.
Flying, trample
Creature spells you cast cost {1} less to cast for each 1 life your opponents have lost this turn.

Arco-Flagellant

Squad {2} (As an additional cost to cast this spell, you may pay {2} any number of times. When this creature enters, create that many tokens that are copies of it.)
Arco-Flagellant can't block.
Endurant — Pay 3 life: Arco-Flagellant gains indestructible until end of turn.

Fireball

This spell costs {1} more to cast for each target beyond the first.
Fireball deals X damage divided evenly, rounded down, among any number of targets.

Crackle with Power

Crackle with Power deals five times X damage to each of up to X targets.

Let the Galaxy Burn

Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)
Let the Galaxy Burn deals X plus 2 damage to each creature that didn't enter this turn.

Overmaster

The next instant or sorcery spell you cast this turn can't be countered.
Draw a card.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Tor Wauki the Younger

Reach, lifelink
If another source you control would deal noncombat damage to a permanent or player, it deals that much damage plus 1 to that permanent or player instead.
Whenever you cast an instant or sorcery spell, Tor Wauki the Younger deals 2 damage to any target.

Rain of Daggers

Destroy all creatures target opponent controls. You lose 2 life for each creature destroyed this way.

Hoarding Broodlord

Convoke
Flying
When Hoarding Broodlord enters, search your library for a card, exile it face down, then shuffle. For as long as that card remains exiled, you may play it.
Spells you cast from exile have convoke.

Mountain

Imodane, the Pyrohammer

Whenever an instant or sorcery spell you control that targets only a single creature deals damage to that creature, Imodane deals that much damage to each opponent.

Command Tower

Expensive Taste

Exile the top two cards of target opponent's library face down. You may look at and play those cards for as long as they remain exiled.

Decadent Dragon

Flying, trample
Whenever Decadent Dragon attacks, create a Treasure token.

Decadent Dragon // Expensive Taste

Graveyard Glutton

Ward—Discard a card.
Whenever Graveyard Glutton enters or attacks, exile up to two target cards from graveyards. For each creature card exiled this way, each opponent loses 1 life and you gain 1 life.
Nightbound (If a player casts at least two spells during their own turn, it becomes day next turn.)

Graveyard Trespasser

Ward—Discard a card.
Whenever Graveyard Trespasser enters or attacks, exile up to one target card from a graveyard. If a creature card was exiled this way, each opponent loses 1 life and you gain 1 life.
Daybound (If a player casts no spells during their own turn, it becomes night next turn.)

Graveyard Trespasser // Graveyard Glutton

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Path of Ancestry

Path of Ancestry enters tapped.
{T}: Add one mana of any color in your commander's color identity. When that mana is spent to cast a creature spell that shares a creature type with your commander, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Storm King's Thunder

When you next cast an instant or sorcery spell this turn, copy that spell X times. You may choose new targets for the copies.

Reverberate

Copy target instant or sorcery spell. You may choose new targets for the copy.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Bloodfell Caves

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {B} or {R}.

Lightning Bolt

Lightning Bolt deals 3 damage to any target.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Gamble

Search your library for a card, put that card into your hand, discard a card at random, then shuffle.

Rankle's Prank

Choose one or more —
• Each player discards two cards.
• Each player loses 4 life.
• Each player sacrifices two creatures of their choice.

Dark Ritual

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Swamp

Ob Nixilis of the Black Oath

+2: Each opponent loses 1 life. You gain life equal to the life lost this way.
−2: Create a 5/5 black Demon creature token with flying. You lose 2 life.
−8: You get an emblem with "{1}{B}, Sacrifice a creature: You gain X life and draw X cards, where X is the sacrificed creature's power."
Ob Nixilis of the Black Oath can be your commander.

Rakdos Signet

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Charming Scoundrel

Haste
When Charming Scoundrel enters, choose one —
• Discard a card, then draw a card.
• Create a Treasure token.
• Create a Wicked Role token attached to target creature you control.

Infernal Grasp

Destroy target creature. You lose 2 life.

Spiteful Hexmage

When Spiteful Hexmage enters, create a Cursed Role token attached to target creature you control. (If you control another Role on it, put that one into the graveyard. Enchanted creature is 1/1.)

Demon Bolt

Demon Bolt deals 4 damage to target creature or planeswalker.
Foretell {R} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Red Elemental Blast

Choose one —
• Counter target blue spell.
• Destroy target blue permanent.

Dash Hopes

When you cast this spell, any player may pay 5 life. If a player does, counter Dash Hopes.
Counter target spell.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Rakdos Carnarium

Rakdos Carnarium enters tapped.
When Rakdos Carnarium enters, return a land you control to its owner's hand.
{T}: Add {B}{R}.

Eradicator Valkyrie

Flying, lifelink, hexproof from planeswalkers
Boast — {1}{B}, Sacrifice a creature: Each opponent sacrifices a creature or planeswalker. (Activate only if this creature attacked this turn and only once each turn.)

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Rowan's Grim Search

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
If this spell was bargained, look at the top four cards of your library, then put up to two of them back on top of your library in any order and the rest into your graveyard.
You draw two cards and you lose 2 life.

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap Staff of Compleation.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Tavern Swindler

{T}, Pay 3 life: Flip a coin. If you win the flip, you gain 6 life.

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Deflecting Swat

If you control a commander, you may cast this spell without paying its mana cost.
You may choose new targets for target spell or ability.

Bituminous Blast

Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)
Bituminous Blast deals 4 damage to target creature.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Rowan, Scion of War

Menace
{T}: Spells you cast this turn that are black and/or red cost {X} less to cast, where X is the amount of life you lost this turn. Activate only as a sorcery.

Jadar, Ghoulcaller of Nephalia

At the beginning of your end step, if you control no creatures with decayed, create a 2/2 black Zombie creature token with decayed. (It can't block. When it attacks, sacrifice it at end of combat.)

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Mount Doom

{T}, Pay 1 life: Add {B} or {R}.
{1}{B}{R}, {T}: Mount Doom deals 1 damage to each opponent.
{5}{B}{R}, {T}, Sacrifice Mount Doom and a legendary artifact: Choose up to two creatures, then destroy the rest. Activate only as a sorcery.