Ulcerate

Target creature gets -3/-3 until end of turn. You lose 3 life.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Defiler of Instinct

First strike
As an additional cost to cast red permanent spells, you may pay 2 life. Those spells cost {R} less to cast if you paid life this way. This effect reduces only the amount of red mana you pay.
Whenever you cast a red permanent spell, this creature deals 1 damage to any target.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Atrocious Experiment

Target player mills two cards, draws two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Rowan, Scion of War

Menace
{T}: Spells you cast this turn that are black and/or red cost {X} less to cast, where X is the amount of life you lost this turn. Activate only as a sorcery.

Skeletal Scrying

As an additional cost to cast this spell, exile X cards from your graveyard.
You draw X cards and you lose X life.

Reckless Assault

{1}, Pay 2 life: This enchantment deals 1 damage to any target.

Death Denied

Return X target creature cards from your graveyard to your hand.

Swallowing Plague

Swallowing Plague deals X damage to target creature and you gain X life.

Fevered Suspicion

Each opponent exiles cards from the top of their library until they exile a nonland card. You may cast any number of spells from among those nonland cards without paying their mana costs.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)

Crashing Drawbridge

Defender
{T}: Creatures you control gain haste until end of turn.

Eye of Vecna

When Eye of Vecna enters, you draw a card and you lose 2 life.
At the beginning of your upkeep, you may pay {2}. If you do, you draw a card and you lose 2 life.

Kothophed, Soul Hoarder

Flying
Whenever a permanent owned by another player is put into a graveyard from the battlefield, you draw a card and you lose 1 life.

Allure of the Unknown

Reveal the top six cards of your library. An opponent exiles a nonland card from among them, then you put the rest into your hand. That opponent may cast the exiled card without paying its mana cost.

Consume Spirit

Spend only black mana on X.
Consume Spirit deals X damage to any target and you gain X life.

Overmaster

The next instant or sorcery spell you cast this turn can't be countered.
Draw a card.

Finale of Eternity

Destroy up to three target creatures with toughness X or less. If X is 10 or more, return all creature cards from your graveyard to the battlefield.

Sunbird's Invocation

Whenever you cast a spell from your hand, reveal the top X cards of your library, where X is that spell's mana value. You may cast a spell with mana value X or less from among cards revealed this way without paying its mana cost. Put the rest on the bottom of your library in a random order.

Crypt Incursion

Exile all creature cards from target player's graveyard. You gain 3 life for each card exiled this way.

Fire Covenant

As an additional cost to cast this spell, pay X life.
Fire Covenant deals X damage divided as you choose among any number of target creatures.

Mischievous Poltergeist

Flying
Pay 1 life: Regenerate this creature.

Cut of the Profits

Casualty 3 (As you cast this spell, you may sacrifice a creature with power 3 or greater. When you do, copy this spell.)
You draw X cards and you lose X life.

Street Wraith

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
Cycling—Pay 2 life. (Pay 2 life, Discard this card: Draw a card.)

Deepwood Ghoul

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Past in Flames

Each instant and sorcery card in your graveyard gains flashback until end of turn. The flashback cost is equal to its mana cost.
Flashback {4}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Commune with Lava

Exile the top X cards of your library. Until the end of your next turn, you may play those cards.

Comet Storm

Multikicker {1} (You may pay an additional {1} any number of times as you cast this spell.)
Choose any target, then choose another target for each time this spell was kicked. Comet Storm deals X damage to each of them.

Blood Pact

Target player draws two cards and loses 2 life.

Red Sun's Twilight

Destroy up to X target artifacts. If X is 5 or more, for each artifact destroyed this way, create a token that's a copy of it. Those tokens gain haste. Exile them at the beginning of the next end step.

Soul Channeling

Enchant creature
Pay 2 life: Regenerate enchanted creature.

March of Wretched Sorrow

As an additional cost to cast this spell, you may exile any number of black cards from your hand. This spell costs {2} less to cast for each card exiled this way.
March of Wretched Sorrow deals X damage to target creature or planeswalker and you gain X life.

Damnable Pact

Target player draws X cards and loses X life.

Flame Rift

Flame Rift deals 4 damage to each player.

Descent into Avernus

At the beginning of your upkeep, put two descent counters on this enchantment. Then each player creates X Treasure tokens and this enchantment deals X damage to each player, where X is the number of descent counters on this enchantment.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Stir the Grave

Return target creature card with mana value X or less from your graveyard to the battlefield.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik.

Swamp

Grave Consequences

Each player may exile any number of cards from their graveyard. Then each player loses 1 life for each card in their graveyard.
Draw a card.

Sol Ring

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Dance with Calamity

Shuffle your library. As many times as you choose, you may exile the top card of your library. If the total mana value of the cards exiled this way is 13 or less, you may cast any number of spells from among those cards without paying their mana costs.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Mordor Muster

You draw a card and you lose 1 life.
Amass Orcs 1. (Put a +1/+1 counter on an Army you control. It's also an Orc. If you don't control an Army, create a 0/0 black Orc Army creature token first.)

Vesper Ghoul

{T}, Pay 1 life: Add one mana of any color.

Black Sun's Twilight

Up to one target creature gets -X/-X until end of turn. If X is 5 or more, return a creature card with mana value X or less from your graveyard to the battlefield tapped.

Dark Ritual

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Night's Whisper

Armor of Shadows

Until end of turn, target creature gets +1/+0 and gains indestructible. (Damage and effects that say "destroy" don't destroy it.)

Initiates of the Ebon Hand

{1}: Add {B}. If this ability has been activated four or more times this turn, sacrifice this creature at the beginning of the next end step.

Goblin Motivator

{T}: Target creature gains haste until end of turn. (It can attack and {T} this turn.)

Sins of the Past

Until end of turn, you may cast target instant or sorcery card from your graveyard without paying its mana cost. If that spell would be put into your graveyard, exile it instead. Exile Sins of the Past.

Jaya's Immolating Inferno

(You may cast a legendary sorcery only if you control a legendary creature or planeswalker.)
Jaya's Immolating Inferno deals X damage to each of up to three targets.

Pain's Reward

Each player may bid life. You start the bidding with a bid of any number. In turn order, each player may top the high bid. The bidding ends if the high bid stands. The high bidder loses life equal to the high bid and draws four cards.

Builder's Bane

Destroy X target artifacts. Builder's Bane deals damage to each player equal to the number of artifacts they controlled that were put into a graveyard this way.

Gonti's Machinations

Whenever you lose life for the first time each turn, you get {E}. (You get an energy counter. Damage causes loss of life.)
Pay {E}{E}, Sacrifice this enchantment: Each opponent loses 3 life. You gain life equal to the life lost this way.

Netherborn Altar

{T}, Put a soul counter on this artifact: Put your commander into your hand from the command zone. Then you lose 3 life for each soul counter on this artifact.

By Force

Roiling Vortex

At the beginning of each player's upkeep, this enchantment deals 1 damage to them.
Whenever a player casts a spell, if no mana was spent to cast that spell, this enchantment deals 5 damage to that player.
{R}: Your opponents can't gain life this turn.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Kill-Suit Cultist

This creature attacks each combat if able.
{B}, Sacrifice this creature: The next time damage would be dealt to target creature this turn, destroy that creature instead.

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Infernal Grasp

Destroy target creature. You lose 2 life.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: This creature gets +1/+1 until end of turn.

March of Reckless Joy

As an additional cost to cast this spell, you may exile any number of red cards from your hand. This spell costs {2} less to cast for each card exiled this way.
Exile the top X cards of your library. You may play up to two of those cards until the end of your next turn.