Webspinner Cuff

Reach
Equipped creature gets +1/+4 and has reach.
Reconfigure {4} ({4}: Attach to target creature you control; or unattach from a creature. Reconfigure only as a sorcery. While attached, this isn't a creature.)

Spider

Lolth, Spider Queen Emblem

Whenever an opponent is dealt combat damage by one or more creatures you control, if that player lost less than 8 life this turn, they lose life equal to the difference.

Juvenile Gloomwidow

Reach (This creature can block creatures with flying.)
Wither (This deals damage to creatures in the form of -1/-1 counters.)

Hidden Spider

When an opponent casts a creature spell with flying, if Hidden Spider is an enchantment, Hidden Spider becomes a 3/5 Spider creature with reach. (It can block creatures with flying.)

Spider Umbra

Enchant creature
Enchanted creature gets +1/+1 and has reach. (It can block creatures with flying.)
Umbra armor (If enchanted creature would be destroyed, instead remove all damage from it and destroy this Aura.)

Thantis, the Warweaver

Vigilance, reach
All creatures attack each combat if able.
Whenever a creature attacks you or a planeswalker you control, put a +1/+1 counter on Thantis, the Warweaver.

Mirkwood Spider

Deathtouch
Whenever Mirkwood Spider attacks, target legendary creature you control gains deathtouch until end of turn.

Gloomwidow's Feast

Destroy target creature with flying. If that creature was blue or black, create a 1/2 green Spider creature token with reach. (It can block creatures with flying.)

Swarmyard

{T}: Add {C}.
{T}: Regenerate target Insect, Rat, Spider, or Squirrel. (The next time it would be destroyed this turn, instead tap it, remove it from combat, and heal all damage on it.)

Gloomwidow

Reach
Gloomwidow can block only creatures with flying.

Lolth, Spider Queen

Whenever a creature you control dies, put a loyalty counter on Lolth, Spider Queen.
0: You draw a card and you lose 1 life.
−3: Create two 2/1 black Spider creature tokens with menace and reach.
−8: You get an emblem with "Whenever an opponent is dealt combat damage by one or more creatures you control, if that player lost less than 8 life this turn, they lose life equal to the difference."

Shelob, Dread Weaver

Whenever a nontoken creature an opponent controls dies, exile it.
{2}{B}, Put a creature card exiled with Shelob, Dread Weaver into its owner's graveyard: Put two +1/+1 counters on Shelob. Draw a card.
{X}{1}{B}: Put target creature card with mana value X exiled with Shelob onto the battlefield tapped under your control.

Rotwidow Pack

Reach
{3}{B}{G}, Exile a creature card from your graveyard: Create a 1/2 green Spider creature token with reach, then each opponent loses 1 life for each Spider you control.

Curse of Clinging Webs

Enchant player
Whenever a nontoken creature enchanted player controls dies, exile it and you create a 1/2 green Spider creature token with reach.

Drider

Reach
Whenever Drider deals combat damage to a player, create a 2/1 black Spider creature token with menace and reach.

Watcher in the Web

Reach (This creature can block creatures with flying.)
Watcher in the Web can block an additional seven creatures each combat.

Search for Blex

Look at the top five cards of your library. You may put any number of them into your hand and the rest into your graveyard. You lose 3 life for each card you put into your hand this way.

Blex, Vexing Pest

Other Pests, Bats, Insects, Snakes, and Spiders you control get +1/+1.
When Blex, Vexing Pest dies, you gain 4 life.

Blex, Vexing Pest // Search for Blex

Arasta of the Endless Web

Reach
Whenever an opponent casts an instant or sorcery spell, create a 1/2 green Spider creature token with reach.

Copy

(This token can be used to represent a token that's a copy of a permanent.)

Arachnogenesis

Create X 1/2 green Spider creature tokens with reach, where X is the number of creatures attacking you. Prevent all combat damage that would be dealt this turn by non-Spider creatures.

Twin-Silk Spider

Reach
When Twin-Silk Spider enters, create a 1/2 green Spider creature token with reach.

Mammoth Spider

Reach (This creature can block creatures with flying.)

Shelob, Child of Ungoliant

Deathtouch, ward {2}
Other Spiders you control have deathtouch and ward {2}.
Whenever another creature dealt damage this turn by a Spider you controlled dies, create a token that's a copy of that creature, except it's a Food artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life," and it loses all other card types.

Spidersilk Armor

Creatures you control get +0/+1 and have reach. (They can block creatures with flying.)