Prisoner's Dilemma

Each opponent secretly chooses silence or snitch, then the choices are revealed. If each opponent chose silence, Prisoner's Dilemma deals 4 damage to each of them. If each opponent chose snitch, Prisoner's Dilemma deals 8 damage to each of them. Otherwise, Prisoner's Dilemma deals 12 damage to each opponent who chose silence.
Flashback {5}{R}{R}

Sol Ring

Blood Crypt

({T}: Add {B} or {R}.)
As Blood Crypt enters, you may pay 2 life. If you don't, it enters tapped.

Ancestral Vision

Suspend 4—{U} (Rather than cast this card from your hand, pay {U} and exile it with four time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Target player draws three cards.

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Xander's Lounge

({T}: Add {U}, {B}, or {R}.)
Xander's Lounge enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Steam Vents

({T}: Add {U} or {R}.)
As Steam Vents enters, you may pay 2 life. If you don't, it enters tapped.

Crumbling Necropolis

Crumbling Necropolis enters tapped.
{T}: Add {U}, {B}, or {R}.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Wild-Magic Sorcerer

The first spell you cast from exile each turn has cascade. (When you cast your first spell from exile, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)

Mizzix, Replica Rider

Flying
Whenever you cast a spell from anywhere other than your hand, you may pay {1}{U/R}. If you do, copy that spell and you may choose new targets for the copy. If the copy is a permanent spell, it gains haste and "At the beginning of your end step, sacrifice this permanent." (A copy of a permanent spell becomes a token.)

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Luxury Suite

Luxury Suite enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Blood for the Blood God!

This spell costs {1} less to cast for each creature that died this turn.
Discard your hand, then draw eight cards. Blood for the Blood God! deals 8 damage to each opponent. Exile Blood for the Blood God!

Mount Doom

{T}, Pay 1 life: Add {B} or {R}.
{1}{B}{R}, {T}: Mount Doom deals 1 damage to each opponent.
{5}{B}{R}, {T}, Sacrifice Mount Doom and a legendary artifact: Choose up to two creatures, then destroy the rest. Activate only as a sorcery.

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters, you may pay 2 life. If you don't, it enters tapped.

Kill! Maim! Burn!

Choose one or more —
• Destroy target artifact.
• Destroy target creature.
• Kill! Maim! Burn! deals 3 damage to target player.

Training Center

Training Center enters tapped unless you have two or more opponents.
{T}: Add {U} or {R}.

Island

Volcanic Torrent

Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)
Volcanic Torrent deals X damage to each creature and planeswalker your opponents control, where X is the number of spells you've cast this turn.

Nightscape Familiar

Blue spells and red spells you cast cost {1} less to cast.
{1}{B}: Regenerate Nightscape Familiar.

Warstorm Surge

Whenever a creature you control enters, it deals damage equal to its power to any target.

Heralds of Tzeentch

Flying
Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)

Stormcarved Coast

Stormcarved Coast enters tapped unless you control two or more other lands.
{T}: Add {U} or {R}.

Maestros Charm

Choose one —
• Look at the top five cards of your library. Put one of those cards into your hand and the rest into your graveyard.
• Each opponent loses 3 life and you gain 3 life.
• Maestros Charm deals 5 damage to target creature or planeswalker.

Protection Racket

At the beginning of your upkeep, repeat the following process for each opponent in turn order. Reveal the top card of your library. That player may pay life equal to that card's mana value. If they do, exile that card. Otherwise, put it into your hand.

Abaddon the Despoiler

Trample
Mark of Chaos Ascendant — During your turn, spells you cast from your hand with mana value X or less have cascade, where X is the total amount of life your opponents have lost this turn.

Delayed Blast Fireball

Delayed Blast Fireball deals 2 damage to each opponent and each creature they control. If this spell was cast from exile, it deals 5 damage to each opponent and each creature they control instead.
Foretell {4}{R}{R} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Keeper of Secrets

First strike, haste
Symphony of Pain — Whenever you cast a spell from anywhere other than your hand, Keeper of Secrets deals damage equal to that spell's mana value to target opponent.

City on Fire

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
If a source you control would deal damage to a permanent or player, it deals triple that damage instead.

Let the Galaxy Burn

Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)
Let the Galaxy Burn deals X plus 2 damage to each creature that didn't enter this turn.

Dark Apostle

Gift of Chaos — {3}, {T}: The next noncreature spell you cast this turn has cascade. (When you cast that spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)

The Lost and the Damned

Whenever a land you control enters from anywhere other than your hand or you cast a spell from anywhere other than your hand, create a 3/3 red Spawn creature token.

Swamp

Jeska's Will

Choose one. If you control a commander as you cast this spell, you may choose both instead.
• Add {R} for each card in target opponent's hand.
• Exile the top three cards of your library. You may play them this turn.

Aurora of Emrakul

Flying, deathtouch
Whenever Aurora of Emrakul attacks, each opponent loses 3 life.

Cryptolith Fragment

Cryptolith Fragment enters tapped.
{T}: Add one mana of any color. Each player loses 1 life.
At the beginning of your upkeep, if each player has 10 or less life, transform Cryptolith Fragment.

Cryptolith Fragment // Aurora of Emrakul

Nalfeshnee

Flying
Whenever you cast a spell from exile, copy it. You may choose new targets for the copy. If it's a permanent spell, the copy gains haste and "At the beginning of the end step, sacrifice this permanent." (A copy of a permanent spell becomes a token.)

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Haunted Ridge

Haunted Ridge enters tapped unless you control two or more other lands.
{T}: Add {B} or {R}.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Rakdos Charm

Choose one —
• Exile target player's graveyard.
• Destroy target artifact.
• Each creature deals 1 damage to its controller.

Solphim, Mayhem Dominus

If a source you control would deal noncombat damage to an opponent or a permanent an opponent controls, it deals double that damage to that player or permanent instead.
{1}{R/P}{R/P}, Discard two cards: Put an indestructible counter on Solphim, Mayhem Dominus. ({R/P} can be paid with either {R} or 2 life.)

Light Up the Stage

Spectacle {R} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Exile the top two cards of your library. Until the end of your next turn, you may play those cards.

Etherium-Horn Sorcerer

{1}{U}{R}: Return Etherium-Horn Sorcerer to its owner's hand.
Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)

Loyal Subordinate

Menace (This creature can't be blocked except by two or more creatures.)
Lieutenant — At the beginning of combat on your turn, if you control your commander, each opponent loses 3 life.

Flame Rift

Flame Rift deals 4 damage to each player.

Into the Time Vortex

Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)

Rakdos, Lord of Riots

You can't cast this spell unless an opponent lost life this turn.
Flying, trample
Creature spells you cast cost {1} less to cast for each 1 life your opponents have lost this turn.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters tapped unless you control two or more basic lands.

Mana Geyser

Add {R} for each tapped land your opponents control.

Relic of Sauron

{T}: Add two mana in any combination of {U}, {B}, and/or {R}.
{3}, {T}: Draw two cards, then discard a card.

Noise Marine

Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)
Sonic Blaster — When Noise Marine enters, it deals damage equal to the number of spells you've cast this turn to any target.

Past in Flames

Each instant and sorcery card in your graveyard gains flashback until end of turn. The flashback cost is equal to its mana cost.
Flashback {4}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Bituminous Blast

Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)
Bituminous Blast deals 4 damage to target creature.

Prosper, Tome-Bound

Deathtouch
Mystic Arcanum — At the beginning of your end step, exile the top card of your library. Until the end of your next turn, you may play that card.
Pact Boon — Whenever you play a card from exile, create a Treasure token.

Treasure Cruise

Delve (Each card you exile from your graveyard while casting this spell pays for {1}.)
Draw three cards.

Dark Ritual

Dance with Calamity

Shuffle your library. As many times as you choose, you may exile the top card of your library. If the total mana value of the cards exiled this way is 13 or less, you may cast any number of spells from among those cards without paying their mana costs.

Dig Through Time

Delve (Each card you exile from your graveyard while casting this spell pays for {1}.)
Look at the top seven cards of your library. Put two of them into your hand and the rest on the bottom of your library in any order.

Inevitable Betrayal

Suspend 3—{1}{U}{U} (Rather than cast this card from your hand, pay {1}{U}{U} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search target opponent's library for a creature card and put that card onto the battlefield under your control. Then that player shuffles.

Deny Reality

Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)
Return target permanent to its owner's hand.

Call Forth the Tempest

Cascade, cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom of your library in a random order. Then do it again.)
Call Forth the Tempest deals damage to each creature your opponents control equal to the total mana value of other spells you've cast this turn.

Sloppity Bilepiper

Jolly Gutpipes — {2}, {T}, Sacrifice a creature: The next creature spell you cast this turn has cascade. (When you next cast a creature spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)

Descent into Avernus

At the beginning of your upkeep, put two descent counters on Descent into Avernus. Then each player creates X Treasure tokens and Descent into Avernus deals X damage to each player, where X is the number of descent counters on Descent into Avernus.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

The Ruinous Powers

At the beginning of your upkeep, choose an opponent at random. Exile the top card of that player's library. Until end of turn, you may play that card and you may spend mana as though it were mana of any color to cast it. When you cast a spell this way, its owner loses life equal to its mana value.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Fevered Suspicion

Each opponent exiles cards from the top of their library until they exile a nonland card. You may cast any number of spells from among those nonland cards without paying their mana costs.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)

Passionate Archaeologist

Commander creatures you own have "Whenever you cast a spell from exile, this creature deals damage equal to that spell's mana value to target opponent."

Smoldering Marsh

({T}: Add {B} or {R}.)
Smoldering Marsh enters tapped unless you control two or more basic lands.

Shipwreck Marsh

Shipwreck Marsh enters tapped unless you control two or more other lands.
{T}: Add {U} or {B}.

Wheel of Fate

Suspend 4—{1}{R} (Rather than cast this card from your hand, pay {1}{R} and exile it with four time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Each player discards their hand, then draws seven cards.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Neheb, the Eternal

Afflict 3 (Whenever this creature becomes blocked, defending player loses 3 life.)
At the beginning of each of your postcombat main phases, add {R} for each 1 life your opponents have lost this turn.

Etali, Primal Storm

Whenever Etali, Primal Storm attacks, exile the top card of each player's library, then you may cast any number of spells from among those cards without paying their mana costs.