Kaervek's Spite

As an additional cost to cast this spell, sacrifice all permanents you control and discard your hand.
Target player loses 5 life.

Vampire of the Dire Moon

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Shriekmaw

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
When Shriekmaw enters the battlefield, destroy target nonartifact, nonblack creature.
Evoke {1}{B} (You may cast this spell for its evoke cost. If you do, it's sacrificed when it enters the battlefield.)

Bloodsoaked Champion

Bloodsoaked Champion can't block.
Raid — {1}{B}: Return Bloodsoaked Champion from your graveyard to the battlefield. Activate only if you attacked this turn.

Shambling Ghast

When Shambling Ghast dies, choose one —
• Brave the Stench — Target creature an opponent controls gets -1/-1 until end of turn.
• Search the Body — Create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Dash Hopes

When you cast this spell, any player may pay 5 life. If a player does, counter Dash Hopes.
Counter target spell.

Knight of the Ebon Legion

{2}{B}: Knight of the Ebon Legion gets +3/+3 and gains deathtouch until end of turn.
At the beginning of your end step, if a player lost 4 or more life this turn, put a +1/+1 counter on Knight of the Ebon Legion. (Damage causes loss of life.)

Smuggler's Copter

Flying
Whenever Smuggler's Copter attacks or blocks, you may draw a card. If you do, discard a card.
Crew 1 (Tap any number of creatures you control with total power 1 or more: This Vehicle becomes an artifact creature until end of turn.)

Swamp

Go for the Throat

Vampire Neonate

{2}, {T}: Each opponent loses 1 life and you gain 1 life.

Consume Spirit

Spend only black mana on X.
Consume Spirit deals X damage to any target and you gain X life.

Night's Whisper

Vampire Lacerator

At the beginning of your upkeep, you lose 1 life unless an opponent has 10 or less life.

Cut Down

Destroy target creature with total power and toughness 5 or less.

Vampire's Kiss

Target player loses 2 life and you gain 2 life. Create two Blood tokens. (They're artifacts with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")

Blood Pet

Skullclamp

Equipped creature gets +1/-1.
Whenever equipped creature dies, draw two cards.
Equip {1}

Vraan, Executioner Thane

Whenever one or more other creatures you control die, each opponent loses 2 life and you gain 2 life. This ability triggers only once each turn.

Choking Sands

Destroy target non-Swamp land. If that land was nonbasic, Choking Sands deals 2 damage to the land's controller.

Gonti's Machinations

Whenever you lose life for the first time each turn, you get {E}. (You get an energy counter. Damage causes loss of life.)
Pay {E}{E}, Sacrifice Gonti's Machinations: Each opponent loses 3 life. You gain life equal to the life lost this way.

Carnophage

At the beginning of your upkeep, tap Carnophage unless you pay 1 life.

Evolved Sleeper

{B}: Evolved Sleeper becomes a Human Cleric with base power and toughness 2/2.
{1}{B}: If Evolved Sleeper is a Cleric, put a deathtouch counter on it and it becomes a Phyrexian Human Cleric with base power and toughness 3/3.
{1}{B}{B}: If Evolved Sleeper is a Phyrexian, put a +1/+1 counter on it, then you draw a card and you lose 1 life.

Transmogrant's Crown

Equipped creature gets +2/+0.
Whenever equipped creature dies, draw a card.
Equip {2} or {B}

Fatal Push

Destroy target creature if it has mana value 2 or less.
Revolt — Destroy that creature if it has mana value 4 or less instead if a permanent you controlled left the battlefield this turn.

Nighthawk Scavenger

Flying, deathtouch, lifelink
Nighthawk Scavenger's power is equal to 1 plus the number of card types among cards in your opponents' graveyards.

Throne of Death

At the beginning of your upkeep, mill a card.
{2}{B}, {T}, Exile a creature card from your graveyard: Draw a card.

Egon, God of Death

Deathtouch
At the beginning of your upkeep, exile two cards from your graveyard. If you can't, sacrifice Egon and draw a card.

Egon, God of Death // Throne of Death

Qarsi Sadist

Exploit (When this creature enters the battlefield, you may sacrifice a creature.)
When Qarsi Sadist exploits a creature, target opponent loses 2 life and you gain 2 life.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature, then sacrifices a land.

Night Market Lookout

Whenever Night Market Lookout becomes tapped, each opponent loses 1 life and you gain 1 life.

Dark Ritual

Sign in Blood

Target player draws two cards and loses 2 life.

Serrated Scorpion

When Serrated Scorpion dies, it deals 2 damage to each opponent and you gain 2 life.

Jadar, Ghoulcaller of Nephalia

At the beginning of your end step, if you control no creatures with decayed, create a 2/2 black Zombie creature token with decayed. (It can't block. When it attacks, sacrifice it at end of combat.)

Dismember

({B/P} can be paid with either {B} or 2 life.)
Target creature gets -5/-5 until end of turn.

Bile Urchin

Sacrifice Bile Urchin: Target player loses 1 life.

Vicious Conquistador

Whenever Vicious Conquistador attacks, each opponent loses 1 life.

Nether Traitor

Haste
Shadow (This creature can block or be blocked by only creatures with shadow.)
Whenever another creature is put into your graveyard from the battlefield, you may pay {B}. If you do, return Nether Traitor from your graveyard to the battlefield.

Tyrant's Choice

Will of the council — Starting with you, each player votes for death or torture. If death gets more votes, each opponent sacrifices a creature. If torture gets more votes or the vote is tied, each opponent loses 4 life.

Mind Twist

Target player discards X cards at random.

Loyal Subordinate

Menace
Lieutenant — At the beginning of combat on your turn, if you control your commander, each opponent loses 3 life.

Reassembling Skeleton

{1}{B}: Return Reassembling Skeleton from your graveyard to the battlefield tapped.

Cabal Therapist

Menace
At the beginning of your precombat main phase, you may sacrifice a creature. When you do, choose a nonland card name, then target player reveals their hand and discards all cards with that name.

Cabal Therapy

Choose a nonland card name. Target player reveals their hand and discards all cards with that name.
Flashback—Sacrifice a creature. (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Tragic Slip

Target creature gets -1/-1 until end of turn.
Morbid — That creature gets -13/-13 until end of turn instead if a creature died this turn.

Oubliette

When Oubliette enters the battlefield, target creature phases out until Oubliette leaves the battlefield. Tap that creature as it phases in this way. (Auras and Equipment phase out with it. While permanents are phased out, they're treated as though they don't exist.)

Etched Familiar

When Etched Familiar dies, each opponent loses 2 life and you gain 2 life.

Spawn of Mayhem

Spectacle {1}{B}{B} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Flying, trample
At the beginning of your upkeep, Spawn of Mayhem deals 1 damage to each player. Then if you have 10 or less life, put a +1/+1 counter on Spawn of Mayhem.

Banehound

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Measure of Wickedness

At the beginning of your end step, sacrifice Measure of Wickedness and you lose 8 life.
Whenever another card is put into your graveyard from anywhere, target opponent gains control of Measure of Wickedness.

Annihilating Glare

As an additional cost to cast this spell, pay {4} or sacrifice an artifact or creature.
Destroy target creature or planeswalker.

Viscera Seer

Sacrifice a creature: Scry 1. (Look at the top card of your library. You may put that card on the bottom of your library.)

Sovereign's Bite

Target player loses 3 life and you gain 3 life.

Feign Death

Until end of turn, target creature gains "When this creature dies, return it to the battlefield tapped under its owner's control with a +1/+1 counter on it."

Sunscorched Desert

When Sunscorched Desert enters the battlefield, it deals 1 damage to target player or planeswalker.
{T}: Add {C}.

Contaminated Ground

Enchant land
Enchanted land is a Swamp.
Whenever enchanted land becomes tapped, its controller loses 2 life.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Unearth

Return target creature card with mana value 3 or less from your graveyard to the battlefield.
Cycling {2} ({2}, Discard this card: Draw a card.)

Trespasser's Curse

Enchant player
Whenever a creature enters the battlefield under enchanted player's control, that player loses 1 life and you gain 1 life.

Phyrexian Vivisector

Whenever a creature you control dies, scry 1. (Look at the top card of your library. You may put that card on the bottom of your library.)

Gifted Aetherborn

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Bone Shards

As an additional cost to cast this spell, sacrifice a creature or discard a card.
Destroy target creature or planeswalker.

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature enters the battlefield under your control, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Hope of Ghirapur

Flying
Sacrifice Hope of Ghirapur: Until your next turn, target player who was dealt combat damage by Hope of Ghirapur this turn can't cast noncreature spells.

Geralf's Messenger

Geralf's Messenger enters the battlefield tapped.
When Geralf's Messenger enters the battlefield, target opponent loses 2 life.
Undying (When this creature dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)