Damnation

Destroy all creatures. They can't be regenerated.

Delirium Skeins

Sol Ring

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Infernal Grasp

Destroy target creature. You lose 2 life.

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Liliana, Waker of the Dead

+1: Each player discards a card. Each opponent who can't loses 3 life.
−3: Target creature gets -X/-X until end of turn, where X is the number of cards in your graveyard.
−7: You get an emblem with "At the beginning of combat on your turn, put target creature card from a graveyard onto the battlefield under your control. It gains haste."

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Professor Onyx

Magecraft — Whenever you cast or copy an instant or sorcery spell, each opponent loses 2 life and you gain 2 life.
+1: You lose 1 life. Look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
−3: Each opponent sacrifices a creature with the greatest power among creatures that player controls.
−8: Each opponent may discard a card. If they don't, they lose 3 life. Repeat this process six more times.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Oppression

Whenever a player casts a spell, that player discards a card.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature.

Burglar Rat

When Burglar Rat enters, each opponent discards a card.

Junji, the Midnight Sky

Flying, menace
When Junji, the Midnight Sky dies, choose one —
• Each opponent discards two cards and loses 2 life.
• Put target non-Dragon creature card from a graveyard onto the battlefield under your control. You lose 2 life.

Unnerve

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Jet Medallion

Black spells you cast cost {1} less to cast.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Tourach, Dread Cantor

Kicker {B}{B} (You may pay an additional {B}{B} as you cast this spell.)
Protection from white
Whenever an opponent discards a card, put a +1/+1 counter on Tourach, Dread Cantor.
When Tourach enters, if it was kicked, target opponent discards two cards at random.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Sign in Blood

Target player draws two cards and loses 2 life.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Pilfer

Target opponent reveals their hand. You choose a nonland card from it. That player discards that card.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Virus Beetle

When Virus Beetle enters, each opponent discards a card.

Words of Waste

{1}: The next time you would draw a card this turn, each opponent discards a card instead.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Liliana of the Veil

+1: Each player discards a card.
−2: Target player sacrifices a creature.
−6: Separate all permanents target player controls into two piles. That player sacrifices all permanents in the pile of their choice.

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Elderfang Disciple

When Elderfang Disciple enters, each opponent discards a card.

Go for the Throat

Liliana's Triumph

Each opponent sacrifices a creature. If you control a Liliana planeswalker, each opponent also discards a card.

Mind Rake

Target player discards two cards.
Overload {1}{B} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Ancient Tomb

{T}: Add {C}{C}. Ancient Tomb deals 2 damage to you.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Rankle, Master of Pranks

Flying, haste
Whenever Rankle, Master of Pranks deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature.

Chain of Smog

Target player discards two cards. That player may copy this spell and may choose a new target for that copy.

Dark Ritual

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Charcoal Diamond

Charcoal Diamond enters tapped.
{T}: Add {B}.

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature.
• Each opponent sacrifices a creature token.
• Each opponent sacrifices a planeswalker.

Plaguecrafter

When Plaguecrafter enters, each player sacrifices a creature or planeswalker. Each player who can't discards a card.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Reliquary Tower

Orcish Bowmasters

Flash
When Orcish Bowmasters enters and whenever an opponent draws a card except the first one they draw in each of their draw steps, Orcish Bowmasters deals 1 damage to any target. Then amass Orcs 1.

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This creature can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Davriel, Rogue Shadowmage

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, Davriel, Rogue Shadowmage deals 2 damage to them.
−1: Target player discards a card.

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature, then sacrifices a land.

Animate Dead

Enchant creature card in a graveyard
When Animate Dead enters, if it's on the battlefield, it loses "enchant creature card in a graveyard" and gains "enchant creature put onto the battlefield with Animate Dead." Return enchanted creature card to the battlefield under your control and attach Animate Dead to it. When Animate Dead leaves the battlefield, that creature's controller sacrifices it.
Enchanted creature gets -1/-0.

Cabal Stronghold

{T}: Add {C}.
{3}, {T}: Add {B} for each basic Swamp you control.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Rotting Rats

When Rotting Rats enters, each player discards a card.
Unearth {1}{B} ({1}{B}: Return this card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step or if it would leave the battlefield. Unearth only as a sorcery.)

Doom Blade

Nezumi Informant

When Nezumi Informant enters, each opponent discards a card.

Mana Crypt

At the beginning of your upkeep, flip a coin. If you lose the flip, Mana Crypt deals 3 damage to you.
{T}: Add {C}{C}.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Phyrexian Altar

Sacrifice a creature: Add one mana of any color.

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Anvil of Bogardan

Players have no maximum hand size.
At the beginning of each player's draw step, that player draws an additional card, then discards a card.