Jace, the Perfected Mind

Compleated ({U/P} can be paid with {U} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
+1: Until your next turn, up to one target creature gets -3/-0.
−2: Target player mills three cards. Then if a graveyard has twenty or more cards in it, you draw three cards. Otherwise, you draw a card.
−X: Target player mills three times X cards.

Xanathar, Guild Kingpin

At the beginning of your upkeep, choose target opponent. Until end of turn, that player can't cast spells, you may look at the top card of their library any time, you may play the top card of their library, and you may spend mana as though it were mana of any color to cast spells this way.

Ashiok, Sculptor of Fears

+2: Draw a card. Each player mills two cards.
−5: Put target creature card from a graveyard onto the battlefield under your control.
−11: Gain control of all creatures target opponent controls.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters the battlefield tapped unless you control two or more basic lands.

Mind's Dilation

Whenever an opponent casts their first spell each turn, that player exiles the top card of their library. If it's a nonland card, you may cast it without paying its mana cost.

Nevinyrral's Disk

Nevinyrral's Disk enters the battlefield tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Guard Gomazoa

Defender, flying
Prevent all combat damage that would be dealt to Guard Gomazoa.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Sanity Grinding

Chroma — Reveal the top ten cards of your library. For each blue mana symbol in the mana costs of the revealed cards, target opponent mills a card. Then put the cards you revealed this way on the bottom of your library in any order.

Aetherize

Return all attacking creatures to their owner's hand.

Chill of Foreboding

Each player mills five cards.
Flashback {7}{U} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap Staff of Compleation.

Swamp

Siphon Insight

Look at the top two cards of target opponent's library. Exile one of them face down and put the other on the bottom of that library. You may play the exiled card for as long as it remains exiled, and you may spend mana as though it were mana of any color to cast that spell.
Flashback {1}{U}{B}

Phenax, God of Deception

Indestructible
As long as your devotion to blue and black is less than seven, Phenax isn't a creature.
Creatures you control have "{T}: Target player mills X cards, where X is this creature's toughness."

Island

Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Explore the Vastlands

Each player looks at the top five cards of their library and may reveal a land card and/or an instant or sorcery card from among them. Each player puts the cards they revealed this way into their hand and the rest on the bottom of their library in a random order. Each player gains 3 life.

Wandering Archaic

Whenever an opponent casts an instant or sorcery spell, they may pay {2}. If they don't, you may copy that spell. You may choose new targets for the copy.

Wandering Archaic // Explore the Vastlands

Glacial Grasp

Tap target creature. Its controller mills two cards. That creature doesn't untap during its controller's next untap step. (They put the top two cards of their library into their graveyard.)
Draw a card.

Tekuthal, Inquiry Dominus

Flying
If you would proliferate, proliferate twice instead.
{1}{U/P}{U/P}, Remove three counters from among other artifacts, creatures, and planeswalkers you control: Put an indestructible counter on Tekuthal, Inquiry Dominus. ({U/P} can be paid with either {U} or 2 life.)

Reject Imperfection

Counter target spell. If that spell's mana value was 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Knacksaw Clique

Flying
{1}{U}, {Q}: Target opponent exiles the top card of their library. Until end of turn, you may play that card. ({Q} is the untap symbol.)

Fog Bank

Defender, flying
Prevent all combat damage that would be dealt to and dealt by Fog Bank.

Glimpse the Unthinkable

Duskmantle Guildmage

{1}{U}{B}: Whenever a card is put into an opponent's graveyard from anywhere this turn, that player loses 1 life.
{2}{U}{B}: Target player mills two cards.

Arcane Signet

Dimir Signet

Vraska's Fall

Each opponent sacrifices a creature or planeswalker and gets a poison counter.

Weathered Sentinels

Defender, vigilance, reach, trample
Weathered Sentinels can attack players who attacked you during their last turn as though it didn't have defender.
Whenever Weathered Sentinels attacks, it gets +3/+3 and gains indestructible until end of turn.

Tasha, the Witch Queen

Whenever you cast a spell you don't own, create a 3/3 black Demon creature token.
+1: Draw a card. For each opponent, exile up to one target instant or sorcery card from that player's graveyard and put a page counter on it.
−3: You may cast a spell from among cards in exile with page counters on them without paying its mana cost.
Tasha, the Witch Queen can be your commander.

Hand of the Praetors

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Other creatures you control with infect get +1/+1.
Whenever you cast a creature spell with infect, target player gets a poison counter.

Inexorable Tide

Whenever you cast a spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Protection Racket

At the beginning of your upkeep, repeat the following process for each opponent in turn order. Reveal the top card of your library. That player may pay life equal to that card's mana value. If they do, exile that card. Otherwise, put it into your hand.

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters the battlefield, each player gets a poison counter.

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Drowned Secrets

Whenever you cast a blue spell, target player mills two cards.

Psychic Strike

Counter target spell. Its controller mills two cards.

Experimental Augury

Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Flux Channeler

Whenever you cast a noncreature spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Venser, Corpse Puppet

Lifelink, toxic 1
Whenever you proliferate, choose one —
• If you don't control a creature named The Hollow Sentinel, create The Hollow Sentinel, a legendary 3/3 colorless Phyrexian Golem artifact creature token.
• Target artifact creature you control gains flying and lifelink until end of turn.

Karn's Bastion

{T}: Add {C}.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Ashiok's Forerunner

Flash
When Ashiok's Forerunner enters the battlefield, you may search your library and/or graveyard for a card named Ashiok, Sculptor of Fears, reveal it, and put it into your hand. If you search your library this way, shuffle.

Covetous Urge

Target opponent reveals their hand. You choose a nonland card from that player's graveyard or hand and exile it. You may cast that card for as long as it remains exiled, and you may spend mana as though it were mana of any color to cast that spell.

Phyresis Outbreak

Each opponent gets a poison counter. Then each creature your opponents control gets -1/-1 until end of turn for each poison counter its controller has.

Ichormoon Gauntlet

Planeswalkers you control have "[0]: Proliferate" and "[−12]: Take an extra turn after this one."
Whenever you cast a noncreature spell, choose a counter on target permanent. Put an additional counter of that kind on that permanent.

Voidwing Hybrid

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When you proliferate, return Voidwing Hybrid from your graveyard to your hand.

Whispering Specter

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever Whispering Specter deals combat damage to a player, you may sacrifice it. If you do, that player discards a card for each poison counter they have.

The Seedcore

{T}: Add {C}.
{T}: Add one mana of any color. Spend this mana only to cast Phyrexian creature spells.
Corrupted — {T}: Target 1/1 creature gets +2/+1 until end of turn. Activate only if an opponent has three or more poison counters.

Maddening Cacophony

Kicker {3}{U}
Each opponent mills eight cards. If this spell was kicked, instead each opponent mills half their library, rounded up.

Paranoid Delusions

Target player mills three cards.
Cipher (Then you may exile this spell card encoded on a creature you control. Whenever that creature deals combat damage to a player, its controller may cast a copy of the encoded card without paying its mana cost.)

Thought Collapse

Counter target spell. Its controller mills three cards.

Mu Yanling, Sky Dancer

+2: Until your next turn, up to one target creature gets -2/-0 and loses flying.
−3: Create a 4/4 blue Elemental Bird creature token with flying.
−8: You get an emblem with "Islands you control have '{T}: Draw a card.'"

Relic Putrescence

Enchant artifact
Whenever enchanted artifact becomes tapped, its controller gets a poison counter.

Glacial Wall

Disturbing Conversion

Flash
Enchant creature
When Disturbing Conversion enters the battlefield, each player mills two cards.
Enchanted creature gets -X/-0, where X is the number of cards in its controller's graveyard.

Swamp Mosquito

Flying
Whenever Swamp Mosquito attacks and isn't blocked, defending player gets a poison counter. (A player with ten or more poison counters loses the game.)

Curse of the Bloody Tome

Enchant player
At the beginning of enchanted player's upkeep, that player mills two cards.

Drift of Phantasms

Defender (This creature can't attack.)
Flying
Transmute {1}{U}{U} ({1}{U}{U}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Disciple of Deceit

Inspired — Whenever Disciple of Deceit becomes untapped, you may discard a nonland card. If you do, search your library for a card with the same mana value as that card, reveal it, put it into your hand, then shuffle.

Fractured Sanity

Each opponent mills fourteen cards.
Cycling {1}{U} ({1}{U}, Discard this card: Draw a card.)
When you cycle Fractured Sanity, each opponent mills four cards.

Sol Ring

Guildpact Informant

Flying
Whenever Guildpact Informant deals combat damage to a player or planeswalker, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

King Narfi's Betrayal

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Each player mills four cards. Then you may exile a creature or planeswalker card from each graveyard.
II, III — Until end of turn, you may cast spells from among cards exiled with King Narfi's Betrayal, and you may spend mana as though it were mana of any color to cast those spells.

Persistent Nightmare

Skulk (This creature can't be blocked by creatures with greater power.)
When Persistent Nightmare deals combat damage to a player, return it to its owner's hand.

Startled Awake

Target opponent mills thirteen cards.
{3}{U}{U}: Put Startled Awake from your graveyard onto the battlefield transformed. Activate only as a sorcery.

Startled Awake // Persistent Nightmare

Temple of Deceit

Temple of Deceit enters the battlefield tapped.
When Temple of Deceit enters the battlefield, scry 1.
{T}: Add {U} or {B}.

Ornate Kanzashi

{2}, {T}: Target opponent exiles the top card of their library. You may play that card this turn.

Glistening Sphere

Glistening Sphere enters the battlefield tapped.
When Glistening Sphere enters the battlefield, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Hover Barrier

Thrummingbird

Flying
Whenever Thrummingbird deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Scheming Aspirant

Whenever you proliferate, each opponent loses 2 life and you gain 2 life.

Expedition Lookout

Defender
As long as an opponent has eight or more cards in their graveyard, Expedition Lookout can attack as though it didn't have defender and it can't be blocked.

Septic Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever Septic Rats attacks, if defending player is poisoned, it gets +1/+1 until end of turn.