Utter End

Life Insurance

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever a nontoken creature dies, you lose 1 life and create a Treasure token.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Cruel Celebrant

Whenever Cruel Celebrant or another creature or planeswalker you control dies, each opponent loses 1 life and you gain 1 life.

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Fracture

Destroy target artifact, enchantment, or planeswalker.

Sign in Blood

Target player draws two cards and loses 2 life.

Vanish into Eternity

This spell costs {3} more to cast if it targets a creature.
Exile target nonland permanent.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Dawn of Hope

Whenever you gain life, you may pay {2}. If you do, draw a card.
{3}{W}: Create a 1/1 white Soldier creature token with lifelink.

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Deadly Dispute

As an additional cost to cast this spell, sacrifice an artifact or creature.
Draw two cards and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Agent of the Iron Throne

Commander creatures you own have "Whenever an artifact or creature you control is put into a graveyard from the battlefield, each opponent loses 1 life."

Vermin Gorger

{T}, Sacrifice another creature: Each opponent loses 2 life and you gain 2 life.

Shineshadow Snarl

As Shineshadow Snarl enters, you may reveal a Plains or Swamp card from your hand. If you don't, Shineshadow Snarl enters tapped.
{T}: Add {W} or {B}.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Bastion of Remembrance

When Bastion of Remembrance enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Angelic Accord

At the beginning of each end step, if you gained 4 or more life this turn, create a 4/4 white Angel creature token with flying.

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Sanctum Seeker

Whenever a Vampire you control attacks, each opponent loses 1 life and you gain 1 life.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Glass-Cast Heart

Whenever one or more Vampires you control attack, create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")
{B}, {T}, Pay 1 life: Create a 1/1 white and black Vampire creature token with lifelink.
{B}{B}, {T}, Sacrifice Glass-Cast Heart and thirteen Blood tokens: Each opponent loses 13 life and you gain 13 life.

Vampire Nighthawk

Flying
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Nightshade Harvester

Whenever a land an opponent controls enters, that player loses 1 life. Put a +1/+1 counter on Nightshade Harvester.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Return to Dust

Exile target artifact or enchantment. If you cast this spell during your main phase, you may exile up to one other target artifact or enchantment.

Vindicate

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Vault of the Archangel

{T}: Add {C}.
{2}{W}{B}, {T}: Creatures you control gain deathtouch and lifelink until end of turn.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Snow-Covered Swamp

Astarion's Thirst

Exile target creature. Put X +1/+1 counters on a commander creature you control, where X is the power of the creature exiled this way.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Orzhov Signet

Victimize

Choose two target creature cards in your graveyard. Sacrifice a creature. If you do, return the chosen cards to the battlefield tapped.

Despark

Exile target permanent with mana value 4 or greater.

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Ancient Craving

You draw three cards and you lose 3 life.

Feast of the Victorious Dead

At the beginning of your end step, if one or more creatures died this turn, you gain that much life and distribute that many +1/+1 counters among creatures you control.

Ambition's Cost

Malakir Bloodwitch

Flying, protection from white
When Malakir Bloodwitch enters, each opponent loses life equal to the number of Vampires you control. You gain life equal to the life lost this way.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Sigarda's Splendor

As Sigarda's Splendor enters, note your life total.
At the beginning of your upkeep, draw a card if your life total is greater than or equal to the last noted life total for Sigarda's Splendor. Then note your life total.
Whenever you cast a white spell, you gain 1 life.

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Sol Ring

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Damnable Pact

Target player draws X cards and loses X life.

Mortify

Vampire Neonate

{2}, {T}: Each opponent loses 1 life and you gain 1 life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Greed

Isolation Cell

Whenever an opponent casts a creature spell, that player loses 2 life unless they pay {2}.

Mage Hunter

Whenever an opponent casts or copies an instant or sorcery spell, they lose 1 life.

Village Rites

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Legions to Ashes

Exile target nonland permanent an opponent controls and all tokens that player controls with the same name as that permanent.

Tainted Field

{T}: Add {C}.
{T}: Add {W} or {B}. Activate only if you control a Swamp.

Marauding Blight-Priest

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Mavren Fein, Dusk Apostle

Whenever one or more nontoken Vampires you control attack, create a 1/1 white Vampire creature token with lifelink.

Plains

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Death Grasp

Death Grasp deals X damage to any target. You gain X life.

Edgar Markov's Coffin

At the beginning of your upkeep, create a 1/1 white and black Vampire creature token with lifelink and put a bloodline counter on Edgar Markov's Coffin. Then if there are three or more bloodline counters on it, remove those counters and transform it.

Edgar, Charmed Groom

Other Vampires you control get +1/+1.
When Edgar, Charmed Groom dies, return it to the battlefield transformed under its owner's control.

Edgar, Charmed Groom // Edgar Markov's Coffin

Falkenrath Noble

Flying
Whenever Falkenrath Noble or another creature dies, target player loses 1 life and you gain 1 life.

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Disenchant

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Fellwar Stone

Arcane Signet

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.