Dimir Machinations

Look at the top three cards of target player's library. Exile any number of those cards, then put the rest back in any order.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Oblation

The owner of target nonland permanent shuffles it into their library, then draws two cards.

Orzhov Signet

Vessel of Endless Rest

When Vessel of Endless Rest enters the battlefield, put target card from a graveyard on the bottom of its owner's library.
{T}: Add one mana of any color.

Victim of Night

Destroy target non-Vampire, non-Werewolf, non-Zombie creature.

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Darksteel Mutation

Enchant creature
Enchanted creature is an Insect artifact creature with base power and toughness 0/1 and has indestructible, and it loses all other abilities, card types, and creature types.

Mine Excavation

Return target artifact or enchantment card from a graveyard to its owner's hand.
Conspire (As you cast this spell, you may tap two untapped creatures you control that share a color with it. When you do, copy it and you may choose a new target for the copy.)

Palace Siege

As Palace Siege enters the battlefield, choose Khans or Dragons.
• Khans — At the beginning of your upkeep, return target creature card from your graveyard to your hand.
• Dragons — At the beginning of your upkeep, each opponent loses 2 life and you gain 2 life.

Scoured Barrens

Scoured Barrens enters the battlefield tapped.
When Scoured Barrens enters the battlefield, you gain 1 life.
{T}: Add {W} or {B}.

Netherborn Phalanx

When Netherborn Phalanx enters the battlefield, each opponent loses 1 life for each creature they control.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

One Thousand Lashes

Enchant creature
Enchanted creature can't attack or block, and its activated abilities can't be activated.
At the beginning of the upkeep of enchanted creature's controller, that player loses 1 life.

Mortify

Banishing Light

When Banishing Light enters the battlefield, exile target nonland permanent an opponent controls until Banishing Light leaves the battlefield.

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Damnable Pact

Target player draws X cards and loses X life.

Forsaken Sanctuary

Forsaken Sanctuary enters the battlefield tapped.
{T}: Add {W} or {B}.

Disenchant

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Oblivion Ring

When Oblivion Ring enters the battlefield, exile another target nonland permanent.
When Oblivion Ring leaves the battlefield, return the exiled card to the battlefield under its owner's control.

Sign in Blood

Target player draws two cards and loses 2 life.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Pristine Talisman

Obzedat's Aid

Return target permanent card from your graveyard to the battlefield.

Swamp

Profane Command

Choose two —
• Target player loses X life.
• Return target creature card with mana value X or less from your graveyard to the battlefield.
• Target creature gets -X/-X until end of turn.
• Up to X target creatures gain fear until end of turn. (They can't be blocked except by artifact creatures and/or black creatures.)

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Terramorphic Expanse

{T}, Sacrifice Terramorphic Expanse: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Trading Post

{1}, {T}, Discard a card: You gain 4 life.
{1}, {T}, Pay 1 life: Create a 0/1 white Goat creature token.
{1}, {T}, Sacrifice a creature: Return target artifact card from your graveyard to your hand.
{1}, {T}, Sacrifice an artifact: Draw a card.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Dimir House Guard

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
Sacrifice a creature: Regenerate Dimir House Guard.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Demonic Collusion

Buyback—Discard two cards. (You may discard two cards in addition to any other costs as you cast this spell. If you do, put this card into your hand as it resolves.)
Search your library for a card, put that card into your hand, then shuffle.

Tainted Field

{T}: Add {C}.
{T}: Add {W} or {B}. Activate only if you control a Swamp.

Codex Shredder

{T}: Target player mills a card. (They put the top card of their library into their graveyard.)
{5}, {T}, Sacrifice Codex Shredder: Return target card from your graveyard to your hand.

Divine Reckoning

Each player chooses a creature they control. Destroy the rest.
Flashback {5}{W}{W} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Ambition's Cost

You draw three cards and you lose 3 life.

Unstable Obelisk

{T}: Add {C}.
{7}, {T}, Sacrifice Unstable Obelisk: Destroy target permanent.

Selenia, Dark Angel

Flying
Pay 2 life: Return Selenia, Dark Angel to its owner's hand.

Treasury Thrull

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever Treasury Thrull attacks, you may return target artifact, creature, or enchantment card from your graveyard to your hand.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Increasing Ambition

Search your library for a card and put that card into your hand. If this spell was cast from a graveyard, instead search your library for two cards and put those cards into your hand. Then shuffle.
Flashback {7}{B} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Near-Death Experience

At the beginning of your upkeep, if you have exactly 1 life, you win the game.

Fate Forgotten

Greed

Orzhov Guildgate

Orzhov Guildgate enters the battlefield tapped.
{T}: Add {W} or {B}.

Devour in Shadow

Destroy target creature. It can't be regenerated. You lose life equal to that creature's toughness.

Hex Parasite

{X}{B/P}: Remove up to X counters from target permanent. For each counter removed this way, Hex Parasite gets +1/+0 until end of turn. ({B/P} can be paid with either {B} or 2 life.)

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.

Everflowing Chalice

Multikicker {2} (You may pay an additional {2} any number of times as you cast this spell.)
Everflowing Chalice enters the battlefield with a charge counter on it for each time it was kicked.
{T}: Add {C} for each charge counter on Everflowing Chalice.

Burnished Hart

{3}, Sacrifice Burnished Hart: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Prismatic Lens

{T}: Add {C}.
{1}, {T}: Add one mana of any color.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Plains

Underworld Coinsmith

Constellation — Whenever Underworld Coinsmith or another enchantment enters the battlefield under your control, you gain 1 life.
{W}{B}, Pay 1 life: Each opponent loses 1 life.

Evolving Wilds

{T}, Sacrifice Evolving Wilds: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Skeletal Scrying

As an additional cost to cast this spell, exile X cards from your graveyard.
You draw X cards and you lose X life.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Pillory of the Sleepless

Enchant creature
Enchanted creature can't attack or block.
Enchanted creature has "At the beginning of your upkeep, you lose 1 life."

Orzhov Charm

Choose one —
• Return target creature you control and all Auras you control attached to it to their owner's hand.
• Destroy target creature and you lose life equal to its toughness.
• Return target creature card with mana value 1 or less from your graveyard to the battlefield.

Brainspoil

Destroy target creature that isn't enchanted. It can't be regenerated.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Ancient Craving

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Shred Memory

Exile up to four target cards from a single graveyard.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.