Descent into Madness

At the beginning of your upkeep, put a despair counter on this enchantment, then each player exiles X permanents they control and/or cards from their hand, where X is the number of despair counters on this enchantment.

Infernal Tribute

{2}, Sacrifice a nontoken permanent: Draw a card.

Seal of Doom

Sacrifice this enchantment: Destroy target nonblack creature. It can't be regenerated.

Vesper Ghoul

{T}, Pay 1 life: Add one mana of any color.

Blood on the Snow

Choose one —
• Destroy all creatures.
• Destroy all planeswalkers.
Then return a creature or planeswalker card with mana value X or less from your graveyard to the battlefield, where X is the amount of {S} spent to cast this spell. ({S} is mana from a snow source.)

Skirge Familiar

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Godless Shrine

({T}: Add {W} or {B}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Talisman of Unity

{T}: Add {C}.
{T}: Add {G} or {W}. This artifact deals 1 damage to you.

Overgrown Tomb

({T}: Add {B} or {G}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Deadly Designs

{2}: Put a plot counter on this enchantment. Any player may activate this ability.
When there are five or more plot counters on this enchantment, sacrifice it. If you do, destroy up to two target creatures.

Mindwrack Harpy

Flying
At the beginning of combat on your turn, each player mills three cards.

Aphemia, the Cacophony

Flying
At the beginning of your end step, you may exile an enchantment card from your graveyard. If you do, create a 2/2 black Zombie creature token.

Brushland

{T}: Add {C}.
{T}: Add {G} or {W}. This land deals 1 damage to you.

Snow-Covered Plains

Null Profusion

Skip your draw step.
Whenever you play a card, draw a card.
Your maximum hand size is two.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. This artifact deals 1 damage to you.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Synod Sanctum

{2}, {T}: Exile target permanent you control.
{2}, Sacrifice this artifact: Return all cards exiled with this artifact to the battlefield under your control.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Snow-Covered Forest

Attrition

{B}, Sacrifice a creature: Destroy target nonblack creature.

Mire Triton

Deathtouch
When this creature enters, mill two cards and you gain 2 life. (To mill a card, put the top card of your library into your graveyard.)

Curse of the Cabal

Target player sacrifices half the permanents they control of their choice, rounded down.
Suspend 2—{2}{B}{B} (Rather than cast this card from your hand, you may pay {2}{B}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
At the beginning of each player's upkeep, if this card is suspended, that player may sacrifice a permanent of their choice. If the player does, put two time counters on this card.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. This land deals 1 damage to you.

Blightsoil Druid

Sunstone

{2}, Sacrifice a snow land: Prevent all combat damage that would be dealt this turn.

Llanowar Wastes

{T}: Add {C}.
{T}: Add {B} or {G}. This land deals 1 damage to you.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Garenbrig Growth

Return target creature or land card from your graveyard to your hand. (Then exile this card. You may cast the enchantment later from exile.)

Virtue of Strength

If you tap a basic land for mana, it produces three times as much of that mana instead.

Virtue of Strength // Garenbrig Growth

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It is every creature type.)

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Claws of Gix

{1}, Sacrifice a permanent: You gain 1 life.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Palantír of Orthanc

At the beginning of your end step, put an influence counter on Palantír of Orthanc and scry 2. Then target opponent may have you draw a card. If that player doesn't, you mill X cards, where X is the number of influence counters on Palantír of Orthanc, and that player loses life equal to the total mana value of those cards.

Midnight Oil

This enchantment enters with seven hour counters on it.
At the beginning of your draw step, draw an additional card and remove two hour counters from this enchantment.
Your maximum hand size is equal to the number of hour counters on this enchantment.
Whenever you discard a card, you lose 1 life.

Anikthea, Hand of Erebos

Menace
Other enchantment creatures you control have menace.
Whenever Anikthea enters or attacks, exile up to one target non-Aura enchantment card from your graveyard. Create a token that's a copy of that card, except it's a 3/3 black Zombie creature in addition to its other types.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle this card, all creatures get -2/-2 until end of turn.

Demon of Fate's Design

Flying, trample
Once during each of your turns, you may cast an enchantment spell by paying life equal to its mana value rather than paying its mana cost.
{2}{B}, Sacrifice another enchantment: This creature gets +X/+0 until end of turn, where X is the sacrificed enchantment's mana value.

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent of their choice that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Dark Tutelage

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Magus of the Mirror

{T}, Sacrifice this creature: Exchange life totals with target opponent. Activate only during your upkeep.

Damnation

Destroy all creatures. They can't be regenerated.

Grave Peril

When a nonblack creature enters, sacrifice this enchantment. If you do, destroy that creature.

Out of the Tombs

At the beginning of your upkeep, put two eon counters on this enchantment, then mill cards equal to the number of eon counters on it.
If you would draw a card while your library has no cards in it, instead return a creature card from your graveyard to the battlefield. If you can't, you lose the game.

Demonic Pact

At the beginning of your upkeep, choose one that hasn't been chosen —
• This enchantment deals 4 damage to any target and you gain 4 life.
• Target opponent discards two cards.
• Draw two cards.
• You lose the game.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Treacherous Blessing

When this enchantment enters, draw three cards.
Whenever you cast a spell, you lose 1 life.
When this enchantment becomes the target of a spell or ability, sacrifice it.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

No Mercy

Whenever a creature deals damage to you, destroy it.

Phyrexian Tower

{T}: Add {C}.
{T}, Sacrifice a creature: Add {B}{B}.

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Cacophony Unleashed

When this enchantment enters, if you cast it, destroy all nonenchantment creatures.
Whenever this enchantment or another enchantment you control enters, until end of turn, this enchantment becomes a legendary 6/6 Nightmare God creature with menace and deathtouch. It's still an enchantment.

Demonic Lore

When this enchantment enters, draw three cards.
At the beginning of your end step, you lose 2 life for each card in your hand.

Dark Confidant

Temple Garden

({T}: Add {G} or {W}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Talisman of Resilience

{T}: Add {C}.
{T}: Add {B} or {G}. This artifact deals 1 damage to you.

Tymaret Calls the Dead

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — Mill three cards. Then you may exile a creature or enchantment card from your graveyard. If you do, create a 2/2 black Zombie creature token.
III — You gain X life and scry X, where X is the number of Zombies you control.

Hall of Heliod's Generosity

{T}: Add {C}.
{1}{W}, {T}: Put target enchantment card from your graveyard on top of your library.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Sol Ring

Snow-Covered Swamp

Cemetery Tampering

Hideaway 5 (When this enchantment enters, look at the top five cards of your library, exile one face down, then put the rest on the bottom in a random order.)
At the beginning of your upkeep, you may mill three cards. Then if there are twenty or more cards in your graveyard, you may play the exiled card without paying its mana cost.

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Bog Witch

Perpetual Timepiece

{T}: Mill two cards.
{2}, Exile this artifact: Shuffle any number of target cards from your graveyard into your library.

Cloudstone Curio

Whenever a nonartifact permanent you control enters, you may return another permanent you control that shares a permanent type with it to its owner's hand.

Doomwake Giant

Constellation — Whenever this creature or another enchantment you control enters, creatures your opponents control get -1/-1 until end of turn.

Forbidden Ritual

Sacrifice a nontoken permanent. If you do, target opponent loses 2 life unless that player sacrifices a permanent of their choice or discards a card. You may repeat this process any number of times.

Phyrexian Etchings

Cumulative upkeep {B} (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
At the beginning of your end step, draw a card for each age counter on this enchantment.
When this enchantment is put into a graveyard from the battlefield, you lose 2 life for each age counter on it.

Hissing Miasma

Whenever a creature attacks you, its controller loses 1 life.

God-Eternal Bontu

Menace
When God-Eternal Bontu enters, sacrifice any number of other permanents, then draw that many cards.
When God-Eternal Bontu dies or is put into exile from the battlefield, you may put it into its owner's library third from the top.

Command Tower

Black Market

Whenever a creature dies, put a charge counter on this enchantment.
At the beginning of your first main phase, add {B} for each charge counter on this enchantment.

Cunning Rhetoric

Whenever an opponent attacks you and/or one or more planeswalkers you control, exile the top card of that player's library. You may play that card for as long as it remains exiled, and you may spend mana as though it were mana of any color to cast it.

Rite of Belzenlok

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — Create two 0/1 black Cleric creature tokens.
III — Create a 6/6 black Demon creature token with flying, trample, and "At the beginning of your upkeep, sacrifice another creature. If you can't, this token deals 6 damage to you."