Ulamog, the Infinite Gyre

When you cast this spell, destroy target permanent.
Indestructible
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents.)
When Ulamog, the Infinite Gyre is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.

Kozilek, Butcher of Truth

When you cast this spell, draw four cards.
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents.)
When Kozilek, Butcher of Truth is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.

Void Winnower

Your opponents can't cast spells with even mana values. (Zero is even.)
Your opponents can't block with creatures with even mana values.

Ulamog, the Ceaseless Hunger

When you cast this spell, exile two target permanents.
Indestructible
Whenever Ulamog, the Ceaseless Hunger attacks, defending player exiles the top twenty cards of their library.

Reality Smasher

({C} represents colorless mana.)
Trample, haste
Whenever Reality Smasher becomes the target of a spell an opponent controls, counter that spell unless its controller discards a card.

Thought-Knot Seer

({C} represents colorless mana.)
When Thought-Knot Seer enters the battlefield, target opponent reveals their hand. You choose a nonland card from it and exile that card.
When Thought-Knot Seer leaves the battlefield, target opponent draws a card.

Zhulodok, Void Gorger

Colorless spells you cast from your hand with mana value 7 or greater have "Cascade, cascade." (When you cast one, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom of your library in a random order. Then do it again.)

Conduit of Ruin

When you cast this spell, you may search your library for a colorless creature card with mana value 7 or greater, reveal it, then shuffle and put that card on top.
The first creature spell you cast each turn costs {2} less to cast.

Kozilek, the Great Distortion

When you cast this spell, if you have fewer than seven cards in hand, draw cards equal to the difference.
Menace
Discard a card with mana value X: Counter target spell with mana value X.

Matter Reshaper

({C} represents colorless mana.)
When Matter Reshaper dies, reveal the top card of your library. You may put that card onto the battlefield if it's a permanent card with mana value 3 or less. Otherwise, put that card into your hand.

All Is Dust

Each player sacrifices all permanents they control that are one or more colors.

Emrakul, the Promised End

This spell costs {1} less to cast for each card type among cards in your graveyard.
When you cast this spell, you gain control of target opponent during that player's next turn. After that turn, that player takes an extra turn.
Flying, trample, protection from instants

It That Betrays

Annihilator 2 (Whenever this creature attacks, defending player sacrifices two permanents.)
Whenever an opponent sacrifices a nontoken permanent, put that card onto the battlefield under your control.

Flayer of Loyalties

When you cast this spell, gain control of target creature until end of turn. Untap that creature. Until end of turn, it has base power and toughness 10/10, and gains trample, annihilator 2, and haste.
Annihilator 2 (Whenever this creature attacks, defending player sacrifices two permanents.)
Trample

Endbringer

Untap Endbringer during each other player's untap step.
{T}: Endbringer deals 1 damage to any target.
{C}, {T}: Target creature can't attack or block this turn.
{C}{C}, {T}: Draw a card.

Not of This World

Counter target spell or ability that targets a permanent you control.
This spell costs {7} less to cast if it targets a spell or ability that targets a creature you control with power 7 or greater.