Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Mind Rake

Target player discards two cards.
Overload {1}{B} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

The Eldest Reborn

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Each opponent sacrifices a creature or planeswalker.
II — Each opponent discards a card.
III — Put target creature or planeswalker card from a graveyard onto the battlefield under your control.

Toll of the Invasion

Target opponent reveals their hand. You choose a nonland card from it. That player discards that card.
Amass Zombies 1. (Put a +1/+1 counter on an Army you control. It's also a Zombie. If you don't control an Army, create a 0/0 black Zombie Army creature token first.)

Mind Drain

Target opponent discards two cards, mills a card, and loses 1 life. You gain 1 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Rotting Rats

When Rotting Rats enters the battlefield, each player discards a card.
Unearth {1}{B} ({1}{B}: Return this card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step or if it would leave the battlefield. Unearth only as a sorcery.)

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Earsplitting Rats

When Earsplitting Rats enters the battlefield, each player discards a card.
Discard a card: Regenerate Earsplitting Rats.

Locust Miser

Each opponent's maximum hand size is reduced by two.

Guul Draz Specter

Flying
Guul Draz Specter gets +3/+3 as long as an opponent has no cards in hand.
Whenever Guul Draz Specter deals combat damage to a player, that player discards a card.

Hero's Downfall

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Court of Ambition

When Court of Ambition enters the battlefield, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Blood Divination

As an additional cost to cast this spell, sacrifice a creature.
Draw three cards.

Awaken the Erstwhile

Each player discards all the cards in their hand, then creates that many 2/2 black Zombie creature tokens.

Stabwhisker the Odious

At the beginning of each opponent's upkeep, that player loses 1 life for each card fewer than three in their hand.

Nezumi Shortfang

{1}{B}, {T}: Target opponent discards a card. Then if that player has no cards in hand, flip Nezumi Shortfang.

Nezumi Shortfang // Stabwhisker the Odious

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Bloodhusk Ritualist

Multikicker {B} (You may pay an additional {B} any number of times as you cast this spell.)
When Bloodhusk Ritualist enters the battlefield, target opponent discards a card for each time it was kicked.

Murder

Doom Blade

Go Blank

Target player discards two cards. Then exile that player's graveyard.

Greed

Bone Shards

As an additional cost to cast this spell, sacrifice a creature or discard a card.
Destroy target creature or planeswalker.

Larceny

Whenever a creature you control deals combat damage to a player, that player discards a card.

Sol Ring

Hymn to Tourach

Target player discards two cards at random.

Go for the Throat

Unnerve

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Animus of Night's Reach

Menace (This creature can't be blocked except by two or more creatures.)
Whenever Animus of Night's Reach attacks, it gets +X/+0 until end of turn, where X is the number of creature cards in defending player's graveyard.

The Long Reach of Night

(As this Saga enters and after your draw step, add a lore counter.)
I, II — Each opponent sacrifices a creature unless they discard a card.
III — Exile this Saga, then return it to the battlefield transformed under your control.

The Long Reach of Night // Animus of Night's Reach

Nezumi Informant

When Nezumi Informant enters the battlefield, each opponent discards a card.

Drill Bit

Spectacle {B} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Target player reveals their hand. You choose a nonland card from it. That player discards that card.

Extract the Truth

Choose one —
• Target opponent reveals their hand. You may choose a creature, enchantment, or planeswalker card from it. That player discards that card.
• Target opponent sacrifices an enchantment.

Delirium Skeins

Stronghold Rats

Shadow (This creature can block or be blocked by only creatures with shadow.)
Whenever Stronghold Rats deals combat damage to a player, each player discards a card.

Orzhov Racketeers

Whenever Orzhov Racketeers deals combat damage to a player, that player discards a card.
Afterlife 2 (When this creature dies, create two 1/1 white and black Spirit creature tokens with flying.)

Skullslither Worm

When Skullslither Worm enters the battlefield, each opponent discards a card. For each opponent who can't, put two +1/+1 counters on Skullslither Worm.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Virus Beetle

When Virus Beetle enters the battlefield, each opponent discards a card.

Pilfer

Target opponent reveals their hand. You choose a nonland card from it. That player discards that card.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Creeping Dread

At the beginning of your upkeep, each player discards a card. Each opponent who discarded a card that shares a card type with the card you discarded loses 3 life. (Players reveal the discarded cards simultaneously.)

Wheel of Torture

At the beginning of each opponent's upkeep, Wheel of Torture deals X damage to that player, where X is 3 minus the number of cards in their hand.

Aim for the Head

Choose one —
• Exile target Zombie.
• Target opponent exiles two cards from their hand.

Burglar Rat

When Burglar Rat enters the battlefield, each opponent discards a card.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Cast Down

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Elderfang Disciple

When Elderfang Disciple enters the battlefield, each opponent discards a card.

Fell Specter

Flying
When Fell Specter enters the battlefield, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Demon's Disciple

When Demon's Disciple enters the battlefield, each player sacrifices a creature or planeswalker.

Never Happened

Target opponent reveals their hand. You choose a nonland card from that player's graveyard or hand and exile it.

Miasmic Mummy

When Miasmic Mummy enters the battlefield, each player discards a card.

Funeral Charm

Choose one —
• Target player discards a card.
• Target creature gets +2/-1 until end of turn.
• Target creature gains swampwalk until end of turn. (It can't be blocked as long as defending player controls a Swamp.)

Davriel, Rogue Shadowmage

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, Davriel, Rogue Shadowmage deals 2 damage to them.
−1: Target player discards a card.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature, then sacrifices a land.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

The Cruelty of Gix

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.
II — Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.
III — Put target creature card from a graveyard onto the battlefield under your control.

Gnat Miser

Each opponent's maximum hand size is reduced by one.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Mind Rot

You Are Already Dead

Destroy target creature that was dealt damage this turn.
Draw a card.

Eaten Alive

As an additional cost to cast this spell, sacrifice a creature or pay {3}{B}.
Exile target creature or planeswalker.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Liliana's Specter

Flying
When Liliana's Specter enters the battlefield, each opponent discards a card.

Pelakka Caverns

Pelakka Caverns enters the battlefield tapped.
{T}: Add {B}.

Pelakka Predation

Target opponent reveals their hand. You choose a card from it with mana value 3 or greater. That player discards that card.

Pelakka Predation // Pelakka Caverns

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Plaguecrafter

When Plaguecrafter enters the battlefield, each player sacrifices a creature or planeswalker. Each player who can't discards a card.

Nezumi Bone-Reader

{B}, Sacrifice a creature: Target player discards a card. Activate only as a sorcery.

Drainpipe Vermin

When Drainpipe Vermin dies, you may pay {B}. If you do, target player discards a card.

Swamp

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Davriel's Shadowfugue

Target player discards two cards and loses 2 life.

Dark Ritual

Cut Down

Destroy target creature with total power and toughness 5 or less.

Dark Inquiry

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This creature can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Hypnotic Specter

Flying
Whenever Hypnotic Specter deals damage to an opponent, that player discards a card at random.