Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Island

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters, each player gets a poison counter.

Putrefy

Destroy target artifact or creature. It can't be regenerated.

Obscura Storefront

When Obscura Storefront enters, sacrifice it. When you do, search your library for a basic Plains, Island, or Swamp card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Golgari Signet

Phyrexian Atlas

{T}: Add one mana of any color.
Corrupted — Whenever Phyrexian Atlas becomes tapped, each opponent who has three or more poison counters loses 1 life.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Glistener Elf

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Ezuri, Stalker of Spheres

When Ezuri, Stalker of Spheres enters, you may pay {3}. If you do, proliferate twice.
Whenever you proliferate, draw a card.

Evolution Sage

Landfall — Whenever a land you control enters, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Bilious Skulldweller

Deathtouch
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Infectious Bite

Target creature you control deals damage equal to its power to target creature you don't control. Each opponent gets a poison counter.

Cankerbloom

{1}, Sacrifice Cankerbloom: Choose one —
• Destroy target artifact.
• Destroy target enchantment.
• Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Voidwing Hybrid

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When you proliferate, return Voidwing Hybrid from your graveyard to your hand.

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Blightbelly Rat

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Blightbelly Rat dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Skrelv, Defector Mite

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Skrelv, Defector Mite can't block.
{W/P}, {T}: Choose a color. Another target creature you control gains toxic 1 and hexproof from that color until end of turn. It can't be blocked by creatures of that color this turn. ({W/P} can be paid with either {W} or 2 life.)

Esper Panorama

{T}: Add {C}.
{1}, {T}, Sacrifice Esper Panorama: Search your library for a basic Plains, Island, or Swamp card, put it onto the battlefield tapped, then shuffle.

Sol Ring

Simic Signet

Anoint with Affliction

Exile target creature if it has mana value 3 or less.
Corrupted — Exile that creature instead if its controller has three or more poison counters.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.

Venerated Rotpriest

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Whenever a creature you control becomes the target of a spell, target opponent gets a poison counter.

Blight Mamba

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{1}{G}: Regenerate Blight Mamba.

Orzhov Signet

Plague Stinger

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Tekuthal, Inquiry Dominus

Flying
If you would proliferate, proliferate twice instead.
{1}{U/P}{U/P}, Remove three counters from among other artifacts, creatures, and planeswalkers you control: Put an indestructible counter on Tekuthal, Inquiry Dominus. ({U/P} can be paid with either {U} or 2 life.)

Glistening Sphere

Glistening Sphere enters tapped.
When Glistening Sphere enters, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Venomous Brutalizer

Toxic 3 (Players dealt combat damage by this creature also get three poison counters.)
When Venomous Brutalizer enters, you may pay {1}{G}. If you do, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Thriving Heath

Thriving Heath enters tapped. As it enters, choose a color other than white.
{T}: Add {W} or one mana of the chosen color.

Distorted Curiosity

Corrupted — This spell costs {2} less to cast if an opponent has three or more poison counters.
Draw two cards.

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Sandsteppe Citadel

Sandsteppe Citadel enters tapped.
{T}: Add {W}, {B}, or {G}.

Corrupted Resolve

Counter target spell if its controller is poisoned.

Forest

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Command Tower

Tainted Observer

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Whenever another creature you control enters, you may pay {2}. If you do, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Blighted Agent

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Blighted Agent can't be blocked.

Otawara, Soaring City

{T}: Add {U}.
Channel — {3}{U}, Discard Otawara, Soaring City: Return target artifact, creature, enchantment, or planeswalker to its owner's hand. This ability costs {1} less to activate for each legendary creature you control.

Counterspell

Swamp

Experimental Augury

Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Azorius Signet

Thrummingbird

Flying
Whenever Thrummingbird deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Drown in Ichor

Target creature gets -4/-4 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Mirrex

{T}: Add {C}.
{T}: Add one mana of any color. Activate only if Mirrex entered this turn.
{3}, {T}: Create a 1/1 colorless Phyrexian Mite artifact creature token with toxic 1 and "This creature can't block." (Players dealt combat damage by it also get a poison counter.)

Atraxa, Praetors' Voice

Flying, vigilance, deathtouch, lifelink
At the beginning of your end step, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Bring the Ending

Counter target spell unless its controller pays {2}.
Corrupted — Counter that spell instead if its controller has three or more poison counters.

Mortify

Ixhel, Scion of Atraxa

Flying, vigilance, toxic 2
Corrupted — At the beginning of your end step, each opponent who has three or more poison counters exiles the top card of their library face down. You may look at and play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast those spells.

Cut Down

Destroy target creature with total power and toughness 5 or less.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Arcane Sanctum

Arcane Sanctum enters tapped.
{T}: Add {W}, {U}, or {B}.

Bloated Contaminator

Trample
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Whenever Bloated Contaminator deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Plains

Pestilent Syphoner

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Serum Snare

Return target nonland permanent to its owner's hand. If that permanent had mana value 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Go for the Throat

Necrogen Rotpriest

Toxic 2 (Players dealt combat damage by this creature also get two poison counters.)
Whenever a creature you control with toxic deals combat damage to a player, that player gets an additional poison counter.
{1}{B}{G}: Target creature you control with toxic gains deathtouch until end of turn.

Path of Ancestry

Path of Ancestry enters tapped.
{T}: Add one mana of any color in your commander's color identity. When that mana is spent to cast a creature spell that shares a creature type with your commander, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Mother of Runes

{T}: Target creature you control gains protection from the color of your choice until end of turn.

Exotic Orchard

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Skrelv's Hive

At the beginning of your upkeep, you lose 1 life and create a 1/1 colorless Phyrexian Mite artifact creature token with toxic 1 and "This creature can't block."
Corrupted — As long as an opponent has three or more poison counters, creatures you control with toxic have lifelink.

Opulent Palace

Opulent Palace enters tapped.
{T}: Add {B}, {G}, or {U}.

Norn's Decree

Whenever one or more creatures an opponent controls deal combat damage to you, that opponent gets a poison counter.
Whenever a player attacks, if one or more players being attacked are poisoned, the attacking player draws a card.

Dimir Signet

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Brokers Confluence

Choose three. You may choose the same mode more than once.
• Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
• Target creature phases out. (Treat it and anything attached to it as though they don't exist until its controller's next turn.)
• Counter target activated or triggered ability.