Isolate

Exile target permanent with mana value 1.

Illness in the Ranks

Krovikan Plague

Enchant non-Wall creature you control
When Krovikan Plague enters, draw a card at the beginning of the next turn's upkeep.
Tap enchanted creature: Krovikan Plague deals 1 damage to any target. Put a -0/-1 counter on enchanted creature. Activate only if enchanted creature is untapped.

Virulent Plague

Imperial Mask

When Imperial Mask enters, if it's not a token, each of your teammates creates a token that's a copy of Imperial Mask.
You have hexproof. (You can't be the target of spells or abilities your opponents control.)

Spreading Plague

Whenever a creature enters, destroy all other creatures that share a color with it. They can't be regenerated.

Desecration Plague

Folk Medicine

You gain 1 life for each creature you control.
Flashback {1}{W} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Contagion

You may pay 1 life and exile a black card from your hand rather than pay this spell's mana cost.
Distribute two -2/-1 counters among one or two target creatures.

Sickening Shoal

You may exile a black card with mana value X from your hand rather than pay this spell's mana cost.
Target creature gets -X/-X until end of turn.

Traveling Plague

Enchant creature
At the beginning of each upkeep, put a plague counter on Traveling Plague.
Enchanted creature gets -1/-1 for each plague counter on Traveling Plague.
When enchanted creature leaves the battlefield, that creature's controller returns Traveling Plague from its owner's graveyard to the battlefield.

Virulent Swipe

Target creature gets +2/+0 and gains deathtouch until end of turn.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)

Plague Fiend

Whenever Plague Fiend deals combat damage to a creature, destroy that creature unless its controller pays {2}.

Nemesis Mask

All creatures able to block equipped creature do so.
Equip {3} ({3}: Attach to target creature you control. Equip only as a sorcery. This card enters unattached and stays on the battlefield if the creature leaves.)

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Run Away Together

Choose two target creatures controlled by different players. Return those creatures to their owners' hands.

Mask of Immolation

When Mask of Immolation enters, create a 1/1 red Elemental creature token, then attach Mask of Immolation to it.
Equipped creature has "Sacrifice this creature: It deals 1 damage to any target."
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Plague Wind

Destroy all creatures you don't control. They can't be regenerated.

Plaguecrafter

When Plaguecrafter enters, each player sacrifices a creature or planeswalker of their choice. Each player who can't discards a card.

The Cheese Stands Alone

When you control no permanents other than The Cheese Stands Alone and have no cards in hand, you win the game.

Undercity Plague

Target player loses 1 life, discards a card, then sacrifices a permanent of their choice.
Cipher (Then you may exile this spell card encoded on a creature you control. Whenever that creature deals combat damage to a player, its controller may cast a copy of the encoded card without paying its mana cost.)

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Plague Mare

Plague Mare can't be blocked by white creatures.
When Plague Mare enters, creatures your opponents control get -1/-1 until end of turn.

Mask of Memory

Whenever equipped creature deals combat damage to a player, you may draw two cards. If you do, discard a card.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Mask of Law and Grace

Enchant creature
Enchanted creature has protection from black and from red.

Patient Turtle

Patient Turtle enters with two +1/+1 counters on it if you didn't go first this game.

Disease Carriers

When Disease Carriers dies, target creature gets -2/-2 until end of turn.

Plague Beetle

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)

Spread the Sickness

Destroy target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Plague Engineer

Deathtouch
As Plague Engineer enters, choose a creature type.
Creatures of the chosen type your opponents control get -1/-1.

Temporal Isolation

Flash
Enchant creature
Enchanted creature has shadow. (It can block or be blocked by only creatures with shadow.)
Prevent all damage that would be dealt by enchanted creature.

Phyrexian Plaguelord

{T}, Sacrifice Phyrexian Plaguelord: Target creature gets -4/-4 until end of turn.
Sacrifice a creature: Target creature gets -1/-1 until end of turn.

Infectious Horror

Whenever Infectious Horror attacks, each opponent loses 2 life.

Virulent Sliver

All Sliver creatures have poisonous 1. (Whenever a Sliver deals combat damage to a player, that player gets a poison counter. A player with ten or more poison counters loses the game.)

Desperate Research

Choose a card name other than a basic land card name. Reveal the top seven cards of your library and put all of them with that name into your hand. Exile the rest.

Mask of Intolerance

At the beginning of each player's upkeep, if there are four or more basic land types among lands that player controls, Mask of Intolerance deals 3 damage to that player.

Strength of Isolation

Enchant creature
Enchanted creature gets +1/+2 and has protection from black.
Madness {W} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Forsaken Sanctuary

Forsaken Sanctuary enters tapped.
{T}: Add {W} or {B}.

Overburden

Whenever a player puts a nontoken creature onto the battlefield, that player returns a land they control to its owner's hand.

Lost Hours

Target player reveals their hand. You choose a nonland card from it. That player puts that card into their library third from the top.

Uba Mask

If a player would draw a card, that player exiles that card face up instead.
Each player may play lands and cast spells from among cards they exiled with Uba Mask this turn.

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Plague Rats

Plague Rats's power and toughness are each equal to the number of creatures named Plague Rats on the battlefield.

Pestilence Demon

Flying
{B}: Pestilence Demon deals 1 damage to each creature and each player.

Vile Consumption

All creatures have "At the beginning of your upkeep, sacrifice this creature unless you pay 1 life."

Plagued Rusalka

{B}, Sacrifice a creature: Target creature gets -1/-1 until end of turn.

Isolated Watchtower

{T}: Add {C}.
{2}, {T}: Scry 1, then you may reveal the top card of your library. If a basic land card is revealed this way, put it onto the battlefield tapped. Activate only if an opponent controls at least two more lands than you.

Contagious Nim

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Plague Belcher

Menace
When Plague Belcher enters, put two -1/-1 counters on target creature you control.
Whenever another Zombie you control dies, each opponent loses 1 life.

Doomed Traveler

When Doomed Traveler dies, create a 1/1 white Spirit creature token with flying.

Eternal Isolation

Put target creature with power 4 or greater on the bottom of its owner's library.

Plaguebearer

{X}{X}{B}: Destroy target nonblack creature with mana value X.

Guardian of Solitude

Whenever you cast a Spirit or Arcane spell, target creature gains flying until end of turn.

Plague Witch

{B}, {T}, Discard a card: Target creature gets -1/-1 until end of turn.

Necrotic Plague

Enchant creature
Enchanted creature has "At the beginning of your upkeep, sacrifice this creature."
When enchanted creature dies, its controller chooses target creature one of their opponents controls. Return Necrotic Plague from its owner's graveyard to the battlefield attached to that creature.

Karona, False God

Haste
At the beginning of each player's upkeep, that player untaps Karona, False God and gains control of it.
Whenever Karona attacks, creatures of the creature type of your choice get +3/+3 until end of turn.

Plague Boiler

At the beginning of your upkeep, put a plague counter on Plague Boiler.
{1}{B}{G}: Put a plague counter on Plague Boiler or remove a plague counter from it.
When Plague Boiler has three or more plague counters on it, sacrifice it. If you do, destroy all nonland permanents.

Ivory Tower

At the beginning of your upkeep, you gain X life, where X is the number of cards in your hand minus 4.

Pestilence Rats

Pestilence Rats's power is equal to the number of other Rats on the battlefield. (For example, as long as there are two other Rats on the battlefield, Pestilence Rats's power and toughness are 2/3.)

Deserted Temple

{T}: Add {C}.
{1}, {T}: Untap target land.

Plague Spores

Destroy target nonblack creature and target land. They can't be regenerated.

Plague Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{T}: Add {C}.

Isolation Zone

When Isolation Zone enters, exile target creature or enchantment an opponent controls until Isolation Zone leaves the battlefield. (That permanent returns under its owner's control.)

Pestilent Kathari

Flying
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
{2}{R}: Pestilent Kathari gains first strike until end of turn.

Patient Rebuilding

At the beginning of your upkeep, target opponent mills three cards, then you draw a card for each land card put into their graveyard this way.

Medicine Bag

{1}, {T}, Discard a card: Regenerate target creature.

Grunn, the Lonely King

Kicker {3} (You may pay an additional {3} as you cast this spell.)
If Grunn, the Lonely King was kicked, it enters with five +1/+1 counters on it.
Whenever Grunn attacks alone, double its power and toughness until end of turn.

Sick and Tired

Two target creatures each get -1/-1 until end of turn.

Lonely Sandbar

Lonely Sandbar enters tapped.
{T}: Add {U}.
Cycling {U} ({U}, Discard this card: Draw a card.)

Curfew

Each player returns a creature they control to its owner's hand.

Swallowing Plague

Swallowing Plague deals X damage to target creature and you gain X life.

Agent of Masks

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Sicken

Enchant creature
Enchanted creature gets -1/-1.
Cycling {2} ({2}, Discard this card: Draw a card.)

Solitary Confinement

At the beginning of your upkeep, sacrifice Solitary Confinement unless you discard a card.
Skip your draw step.
You have shroud. (You can't be the target of spells or abilities.)
Prevent all damage that would be dealt to you.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Endemic Plague

As an additional cost to cast this spell, sacrifice a creature.
Destroy all creatures that share a creature type with the sacrificed creature. They can't be regenerated.

Hold at Bay

Prevent the next 7 damage that would be dealt to any target this turn.

Illusionary Mask

{X}: You may choose a creature card in your hand whose mana cost could be paid by some amount of, or all of, the mana you spent on {X}. If you do, you may cast that card face down as a 2/2 creature spell without paying its mana cost. If the creature that spell becomes as it resolves has not been turned face up and would assign or deal damage, be dealt damage, or become tapped, instead it's turned face up and assigns or deals damage, is dealt damage, or becomes tapped. Activate only as a sorcery.

Plague Sliver

All Slivers have "At the beginning of your upkeep, this permanent deals 1 damage to you."

Mask of Avacyn

Equipped creature gets +1/+2 and has hexproof. (It can't be the target of spells or abilities your opponents control.)
Equip {3}

Rogue's Gloves

Whenever equipped creature deals combat damage to a player, you may draw a card.
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Mask of Riddles

Equipped creature has fear. (It can't be blocked except by artifact creatures and/or black creatures.)
Whenever equipped creature deals combat damage to a player, you may draw a card.
Equip {2}

Isolation Cell

Whenever an opponent casts a creature spell, that player loses 2 life unless they pay {2}.

Safe Haven

{2}, {T}: Exile target creature you control.
At the beginning of your upkeep, you may sacrifice Safe Haven. If you do, return each card exiled with Safe Haven to the battlefield under its owner's control.

Arrest

Enchant creature
Enchanted creature can't attack or block, and its activated abilities can't be activated.

Alchemist's Refuge

{T}: Add {C}.
{G}{U}, {T}: You may cast spells this turn as though they had flash.

Engineered Plague

As Engineered Plague enters, choose a creature type.
All creatures of the chosen type get -1/-1.

Plague Spitter

At the beginning of your upkeep, Plague Spitter deals 1 damage to each creature and each player.
When Plague Spitter dies, it deals 1 damage to each creature and each player.

Virulent Wound

Put a -1/-1 counter on target creature. When that creature dies this turn, its controller gets a poison counter.

Forsaken City

Forsaken City doesn't untap during your untap step.
At the beginning of your upkeep, you may exile a card from your hand. If you do, untap Forsaken City.
{T}: Add one mana of any color.

Pestilent Spirit

Menace, deathtouch
Instant and sorcery spells you control have deathtouch. (Any amount of damage they deal to a creature is enough to destroy it.)

Instill Infection

Put a -1/-1 counter on target creature.
Draw a card.

Medicine Runner

When Medicine Runner enters, you may remove a counter from target permanent.

Masked Admirers

When Masked Admirers enters, draw a card.
Whenever you cast a creature spell, you may pay {G}{G}. If you do, return Masked Admirers from your graveyard to your hand.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Quarantine Field

Quarantine Field enters with X isolation counters on it.
When Quarantine Field enters, for each isolation counter on it, exile up to one target nonland permanent an opponent controls until Quarantine Field leaves the battlefield.

Kelsien, the Plague

Vigilance, haste
Kelsien, the Plague gets +1/+1 for each experience counter you have.
{T}: Kelsien deals 1 damage to target creature you don't control. When that creature dies this turn, you get an experience counter.

Exotic Disease

Domain — Target player loses X life and you gain X life, where X is the number of basic land types among lands you control.

Abandoned Outpost

Abandoned Outpost enters tapped.
{T}: Add {W}.
{T}, Sacrifice Abandoned Outpost: Add one mana of any color.

Sphere of Safety

Creatures can't attack you or planeswalkers you control unless their controller pays {X} for each of those creatures, where X is the number of enchantments you control.

Plague Dogs

When Plague Dogs dies, all creatures get -1/-1 until end of turn.
{2}, Sacrifice Plague Dogs: Draw a card.