Smallpox

Each player loses 1 life, discards a card, sacrifices a creature, then sacrifices a land.

Butcher of Malakir

Flying
Whenever Butcher of Malakir or another creature you control dies, each opponent sacrifices a creature.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Armillary Sphere

{2}, {T}, Sacrifice Armillary Sphere: Search your library for up to two basic land cards, reveal them, put them into your hand, then shuffle.

Invoke Despair

Target opponent sacrifices a creature. If they can't, they lose 2 life and you draw a card. Then repeat this process for an enchantment and a planeswalker.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Burglar Rat

When Burglar Rat enters, each opponent discards a card.

Spires of Orazca

(Transforms from Thaumatic Compass.)
{T}: Add {C}.
{T}: Untap target attacking creature an opponent controls and remove it from combat.

Thaumatic Compass

{3}, {T}: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.
At the beginning of your end step, if you control seven or more lands, transform Thaumatic Compass.

Thaumatic Compass // Spires of Orazca

Curse of the Cabal

Target player sacrifices half the permanents they control, rounded down.
Suspend 2—{2}{B}{B} (Rather than cast this card from your hand, you may pay {2}{B}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
At the beginning of each player's upkeep, if Curse of the Cabal is suspended, that player may sacrifice a permanent. If the player does, put two time counters on Curse of the Cabal.

Bearer of Silence

Devoid (This card has no color.)
When you cast this spell, you may pay {1}{C}. If you do, target opponent sacrifices a creature. ({C} represents colorless mana.)
Flying
Bearer of Silence can't block.

The Dross Pits

The Dross Pits enters tapped.
{T}: Add {B}.
{1}{B}, {T}, Sacrifice The Dross Pits: Draw a card.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Psychic Miasma

Target player discards a card. If a land card is discarded this way, return Psychic Miasma to its owner's hand.

Cruel Edict

Innocent Blood

Mind Drain

Target opponent discards two cards, mills a card, and loses 1 life. You gain 1 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Scepter of Fugue

{1}{B}, {T}: Target player discards a card. Activate only during your turn.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker and gets a poison counter.

Davriel, Rogue Shadowmage

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, Davriel, Rogue Shadowmage deals 2 damage to them.
−1: Target player discards a card.

Chittering Harvester

Mutate {4}{B} (If you cast this spell for its mutate cost, put it over or under target non-Human creature you own. They mutate into the creature on top plus all abilities from under it.)
Whenever this creature mutates, each opponent sacrifices a creature.

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Vona's Hunger

Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
Each opponent sacrifices a creature. If you have the city's blessing, instead each opponent sacrifices half the creatures they control, rounded up.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Dark Ritual

Mirrex

{T}: Add {C}.
{T}: Add one mana of any color. Activate only if Mirrex entered this turn.
{3}, {T}: Create a 1/1 colorless Phyrexian Mite artifact creature token with toxic 1 and "This creature can't block." (Players dealt combat damage by it also get a poison counter.)

Elderfang Disciple

When Elderfang Disciple enters, each opponent discards a card.

Mindstab

Target player discards three cards.
Suspend 4—{B} (Rather than cast this card from your hand, you may pay {B} and exile it with four time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)

The Eldest Reborn

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Each opponent sacrifices a creature or planeswalker.
II — Each opponent discards a card.
III — Put target creature or planeswalker card from a graveyard onto the battlefield under your control.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Traveler's Amulet

{1}, Sacrifice Traveler's Amulet: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.

Morbid Opportunist

Whenever one or more other creatures die, draw a card. This ability triggers only once each turn.

Chain Devil

Animate Chains — When Chain Devil enters, each player sacrifices a nontoken creature.

Snow-Covered Swamp

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Liliana, Waker of the Dead

+1: Each player discards a card. Each opponent who can't loses 3 life.
−3: Target creature gets -X/-X until end of turn, where X is the number of cards in your graveyard.
−7: You get an emblem with "At the beginning of combat on your turn, put target creature card from a graveyard onto the battlefield under your control. It gains haste."

Plaguecrafter

When Plaguecrafter enters, each player sacrifices a creature or planeswalker. Each player who can't discards a card.

Gix's Command

Choose two —
• Put two +1/+1 counters on up to one creature. It gains lifelink until end of turn.
• Destroy each creature with power 2 or less.
• Return up to two creature cards from your graveyard to your hand.
• Each opponent sacrifices a creature with the highest power among creatures they control.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Hymn to Tourach

Target player discards two cards at random.

Mind Rot

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Syphon Flesh

Each other player sacrifices a creature. You create a 2/2 black Zombie creature token for each creature sacrificed this way.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Noxious Vapors

Each player reveals their hand, chooses one card of each color from it, then discards all other nonland cards.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Pulse of the Dross

Target player reveals three cards from their hand and you choose one of them. That player discards that card. Then if that player has more cards in hand than you, return Pulse of the Dross to its owner's hand.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Sudden Edict

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Target player sacrifices a creature.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Expedition Map

{2}, {T}, Sacrifice Expedition Map: Search your library for a land card, reveal it, put it into your hand, then shuffle.

Cabal Stronghold

{T}: Add {C}.
{3}, {T}: Add {B} for each basic Swamp you control.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Crypt of Agadeem

Crypt of Agadeem enters tapped.
{T}: Add {B}.
{2}, {T}: Add {B} for each black creature card in your graveyard.

Mire in Misery

Each opponent sacrifices a creature or enchantment.

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Barter in Blood

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Soul Shatter

Each opponent sacrifices a creature or planeswalker with the highest mana value among creatures and planeswalkers they control.

Geth's Verdict

Target player sacrifices a creature and loses 1 life.

Black Market

Whenever a creature dies, put a charge counter on Black Market.
At the beginning of your first main phase, add {B} for each charge counter on Black Market.

Phyrexian Obliterator

Trample
Whenever a source deals damage to Phyrexian Obliterator, that source's controller sacrifices that many permanents.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Demogorgon's Clutches

Target opponent discards two cards, mills two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Virus Beetle

When Virus Beetle enters, each opponent discards a card.

Realmbreaker, the Invasion Tree

{2}, {T}: Target opponent mills three cards. Put a land card from their graveyard onto the battlefield tapped under your control. It gains "If this land would leave the battlefield, exile it instead of putting it anywhere else."
{10}, {T}, Sacrifice Realmbreaker, the Invasion Tree: Search your library for any number of Praetor cards, put them onto the battlefield, then shuffle.

Liliana's Triumph

Each opponent sacrifices a creature. If you control a Liliana planeswalker, each opponent also discards a card.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature.
• Each opponent sacrifices a creature token.
• Each opponent sacrifices a planeswalker.