Each player loses a third of their life, then discards a third of the cards in their hand, then sacrifices a third of the creatures they control of their choice, then sacrifices a third of the lands they control of their choice. Round up each time.

Crawlspace

No more than two creatures can attack you each combat.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Fraying Omnipotence

Each player loses half their life, then discards half the cards in their hand, then sacrifices half the creatures they control of their choice. Round up each time.

Blood Crypt

({T}: Add {B} or {R}.)
As Blood Crypt enters, you may pay 2 life. If you don't, it enters tapped.

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Boiling Seas

Wild Guess

As an additional cost to cast this spell, discard a card.
Draw two cards.

Manabarbs

Whenever a player taps a land for mana, Manabarbs deals 1 damage to that player.

Everlasting Torment

Players can't gain life.
Damage can't be prevented.
All damage is dealt as though its source had wither. (A source with wither deals damage to creatures in the form of -1/-1 counters.)

Impending Disaster

At the beginning of your upkeep, if there are seven or more lands on the battlefield, sacrifice Impending Disaster and destroy all lands.

Lightning Bolt

Lightning Bolt deals 3 damage to any target.

Sulfuric Vortex

At the beginning of each player's upkeep, Sulfuric Vortex deals 2 damage to that player.
If a player would gain life, that player gains no life instead.

Animate Dead

Enchant creature card in a graveyard
When Animate Dead enters, if it's on the battlefield, it loses "enchant creature card in a graveyard" and gains "enchant creature put onto the battlefield with Animate Dead." Return enchanted creature card to the battlefield under your control and attach Animate Dead to it. When Animate Dead leaves the battlefield, that creature's controller sacrifices it.
Enchanted creature gets -1/-0.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Damnation

Destroy all creatures. They can't be regenerated.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Vandalblast

Destroy target artifact you don't control.
Overload {4}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Heartless Hidetsugu

{T}: Heartless Hidetsugu deals damage to each player equal to half that player's life total, rounded down.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Reiterate

Buyback {3} (You may pay an additional {3} as you cast this spell. If you do, put this card into your hand as it resolves.)
Copy target instant or sorcery spell. You may choose new targets for the copy.

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Jeska's Will

Choose one. If you control a commander as you cast this spell, you may choose both instead.
• Add {R} for each card in target opponent's hand.
• Exile the top three cards of your library. You may play them this turn.

Defense Grid

Each spell costs {3} more to cast except during its controller's turn.

Wheel of Misfortune

Each player secretly chooses a number 0 or greater, then all players reveal those numbers simultaneously and determine the highest and lowest numbers revealed this way. Wheel of Misfortune deals damage equal to the highest number to each player who chose that number. Each player who didn't choose the lowest number discards their hand, then draws seven cards.

Flashfires

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Smoke

Players can't untap more than one creature during their untap steps.

Purphoros, God of the Forge

Indestructible
As long as your devotion to red is less than five, Purphoros isn't a creature.
Whenever another creature you control enters, Purphoros deals 2 damage to each opponent.
{2}{R}: Creatures you control get +1/+0 until end of turn.

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Orcish Bowmasters

Flash
When Orcish Bowmasters enters and whenever an opponent draws a card except the first one they draw in each of their draw steps, Orcish Bowmasters deals 1 damage to any target. Then amass Orcs 1.

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature of their choice.

Stranglehold

Your opponents can't search libraries.
If an opponent would begin an extra turn, that player skips that turn instead.

Solphim, Mayhem Dominus

If a source you control would deal noncombat damage to an opponent or a permanent an opponent controls, it deals double that damage to that player or permanent instead.
{1}{R/P}{R/P}, Discard two cards: Put an indestructible counter on Solphim, Mayhem Dominus. ({R/P} can be paid with either {R} or 2 life.)

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Thrill of Possibility

Pyroblast

Choose one —
• Counter target spell if it's blue.
• Destroy target permanent if it's blue.

By Force

Incendiary Command

Choose two —
• Incendiary Command deals 4 damage to target player or planeswalker.
• Incendiary Command deals 2 damage to each creature.
• Destroy target nonbasic land.
• Each player discards all the cards in their hand, then draws that many cards.

Tainted Aether

Whenever a creature enters, its controller sacrifices a creature or land of their choice.

Hypnotic Specter

Flying
Whenever Hypnotic Specter deals damage to an opponent, that player discards a card at random.

Price of Progress

Price of Progress deals damage to each player equal to twice the number of nonbasic lands that player controls.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Wild Ricochet

You may choose new targets for target instant or sorcery spell. Then copy that spell. You may choose new targets for the copy.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Abrade

Choose one —
• Abrade deals 3 damage to target creature.
• Destroy target artifact.

Demonic Tutor

Storm Cauldron

Each player may play an additional land during each of their turns.
Whenever a land is tapped for mana, return it to its owner's hand.