Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Chain Reaction

Chain Reaction deals X damage to each creature, where X is the number of creatures on the battlefield.

Magus of the Disk

This creature enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Perplexing Test

Choose one —
• Return all creature tokens to their owners' hands.
• Return all nontoken creatures to their owners' hands.

Door to Nothingness

This artifact enters tapped.
{W}{W}{U}{U}{B}{B}{R}{R}{G}{G}, {T}, Sacrifice this artifact: Target player loses the game.

Athreos, Shroud-Veiled

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
At the beginning of your end step, put a coin counter on another target creature.
Whenever a creature with a coin counter on it dies or is put into exile, return that card to the battlefield under your control.

Ajani Vengeant

+1: Target permanent doesn't untap during its controller's next untap step.
−2: Ajani deals 3 damage to any target and you gain 3 life.
−7: Destroy all lands target player controls.

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Bearer of the Heavens

When this creature dies, destroy all permanents at the beginning of the next end step.

Revel in Riches

Whenever a creature an opponent controls dies, create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")
At the beginning of your upkeep, if you control ten or more Treasures, you win the game.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Prismatic Omen

Lands you control are every basic land type in addition to their other types.

Aetherspouts

For each attacking creature, its owner puts it on their choice of the top or bottom of their library.

Culling Ritual

Destroy each nonland permanent with mana value 2 or less. Add {B} or {G} for each permanent destroyed this way.

Child of Alara

Trample
When Child of Alara dies, destroy all nonland permanents. They can't be regenerated.

Avacyn, Angel of Hope

Flying, vigilance, indestructible
Other permanents you control have indestructible.

Bontu's Last Reckoning

Destroy all creatures. Lands you control don't untap during your next untap step.

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Crux of Fate

Choose one —
• Destroy all Dragon creatures.
• Destroy all non-Dragon creatures.

Assemble the Legion

At the beginning of your upkeep, put a muster counter on this enchantment. Then create a 1/1 red and white Soldier creature token with haste for each muster counter on this enchantment.

Worldslayer

Whenever equipped creature deals combat damage to a player, destroy all permanents other than this Equipment.
Equip {5} ({5}: Attach to target creature you control. Equip only as a sorcery.)

Vanquish the Horde

This spell costs {1} less to cast for each creature on the battlefield.
Destroy all creatures.

Elspeth, Sun's Champion

+1: Create three 1/1 white Soldier creature tokens.
−3: Destroy all creatures with power 4 or greater.
−7: You get an emblem with "Creatures you control get +2/+2 and have flying."

All Is Dust

Each player sacrifices all permanents they control that are one or more colors.

Hour of Reckoning

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy all nontoken creatures.

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Leyline of Anticipation

If this card is in your opening hand, you may begin the game with it on the battlefield.
You may cast spells as though they had flash.

Reckless Endeavor

Roll two d12 and choose one result. Reckless Endeavor deals damage equal to that result to each creature. Then create a number of Treasure tokens equal to the other result.

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Aetherize

Return all attacking creatures to their owner's hand.

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Ondu Skyruins

Ondu Inversion

Ondu Inversion // Ondu Skyruins

Time Wipe

Return a creature you control to its owner's hand, then destroy all creatures.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle this card, all creatures get -2/-2 until end of turn.

Wrath of God

Destroy all creatures. They can't be regenerated.

Ruinous Ultimatum

Destroy all nonland permanents your opponents control.

Rest in Peace

When this enchantment enters, exile all graveyards.
If a card or token would be put into a graveyard from anywhere, exile it instead.

Day of Judgment

Whelming Wave

Return all creatures to their owners' hands except for Krakens, Leviathans, Octopuses, and Serpents.

Marchesa, Resolute Monarch

Menace, deathtouch
Whenever Marchesa attacks, remove all counters from up to one target permanent.
At the beginning of your upkeep, if you haven't been dealt combat damage since your last turn, you draw a card and you lose 1 life.

Invasion of Fiora

(As a Siege enters, choose an opponent to protect it. You and others can attack it. When it's defeated, exile it, then cast it transformed.)
When this Siege enters, choose one or both —
• Destroy all legendary creatures.
• Destroy all nonlegendary creatures.

Invasion of Fiora // Marchesa, Resolute Monarch

Stuffy Doll

Indestructible
As this creature enters, choose a player.
Whenever this creature is dealt damage, it deals that much damage to the chosen player.
{T}: This creature deals 1 damage to itself.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Fall of the Thran

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Destroy all lands.
II, III — Each player returns two land cards from their graveyard to the battlefield.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Elspeth Tirel

+2: You gain 1 life for each creature you control.
−2: Create three 1/1 white Soldier creature tokens.
−5: Destroy all other permanents except for lands and tokens.

Nevinyrral's Disk

This artifact enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.