Big Game Hunter

When Big Game Hunter enters, destroy target creature with power 4 or greater. It can't be regenerated.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Elderfang Disciple

When Elderfang Disciple enters, each opponent discards a card.

Murderous Compulsion

Destroy target tapped creature.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Virus Beetle

When Virus Beetle enters, each opponent discards a card.

Alms of the Vein

Target opponent loses 3 life and you gain 3 life.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Skirge Familiar

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This creature can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Plaguecrafter

When Plaguecrafter enters, each player sacrifices a creature or planeswalker of their choice. Each player who can't discards a card.

Davriel, Rogue Shadowmage

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, Davriel, Rogue Shadowmage deals 2 damage to them.
−1: Target player discards a card.

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Burglar Rat

When this creature enters, each opponent discards a card.

Miasmic Mummy

When Miasmic Mummy enters, each player discards a card.

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Swamp

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Hymn to Tourach

Target player discards two cards at random.

Ichor Slick

Target creature gets -3/-3 until end of turn.
Cycling {2} ({2}, Discard this card: Draw a card.)
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Howling Golem

Whenever Howling Golem attacks or blocks, each player draws a card.

Rotting Rats

When Rotting Rats enters, each player discards a card.
Unearth {1}{B} ({1}{B}: Return this card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step or if it would leave the battlefield. Unearth only as a sorcery.)

Kitchen Imp

Flying, haste
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Bone Shards

As an additional cost to cast this spell, sacrifice a creature or discard a card.
Destroy target creature or planeswalker.

Profane Memento

Whenever a creature card is put into an opponent's graveyard from anywhere, you gain 1 life.

Nezumi Informant

When Nezumi Informant enters, each opponent discards a card.

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Biting Rain

All creatures get -2/-2 until end of turn.
Madness {2}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Psychic Miasma

Target player discards a card. If a land card is discarded this way, return Psychic Miasma to its owner's hand.

The Rack

As The Rack enters, choose an opponent.
At the beginning of the chosen player's upkeep, The Rack deals X damage to that player, where X is 3 minus the number of cards in their hand.

Cursed Rack

As Cursed Rack enters, choose an opponent.
The chosen player's maximum hand size is four.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Gisa's Bidding

Create two 2/2 black Zombie creature tokens.
Madness {2}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)