Each player loses a third of their life, then discards a third of the cards in their hand, then sacrifices a third of the creatures they control of their choice, then sacrifices a third of the lands they control of their choice. Round up each time.

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Professor Onyx

Magecraft — Whenever you cast or copy an instant or sorcery spell, each opponent loses 2 life and you gain 2 life.
+1: You lose 1 life. Look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
−3: Each opponent sacrifices a creature with the greatest power among creatures that player controls.
−8: Each opponent may discard a card. If they don't, they lose 3 life. Repeat this process six more times.

Chain of Smog

Target player discards two cards. That player may copy this spell and may choose a new target for that copy.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Sol Ring

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Sentinel Tower

Whenever an instant or sorcery spell is cast during your turn, Sentinel Tower deals damage to any target equal to 1 plus the number of instant and sorcery spells cast before that spell this turn.

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put Sensei's Divining Top on top of its owner's library.

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Delirium Skeins

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Mind Rake

Target player discards two cards.
Overload {1}{B} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Stronghold Rats

Shadow (This creature can block or be blocked by only creatures with shadow.)
Whenever Stronghold Rats deals combat damage to a player, each player discards a card.

Magus of the Coffers

{2}, {T}: Add {B} for each Swamp you control.

Homeward Path

{T}: Add {C}.
{T}: Each player gains control of all creatures they own.

Bubbling Muck

Until end of turn, whenever a player taps a Swamp for mana, that player adds an additional {B}.

Basalt Monolith

Basalt Monolith doesn't untap during your untap step.
{T}: Add {C}{C}{C}.
{3}: Untap Basalt Monolith.

Rankle, Master of Pranks

Flying, haste
Whenever Rankle, Master of Pranks deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature of their choice.

Awaken the Erstwhile

Each player discards all the cards in their hand, then creates that many 2/2 black Zombie creature tokens.

Ancient Tomb

{T}: Add {C}{C}. Ancient Tomb deals 2 damage to you.

Withering Boon

As an additional cost to cast this spell, pay 3 life.
Counter target creature spell.

Mindslicer

When Mindslicer dies, each player discards their hand.

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Lake of the Dead

If Lake of the Dead would enter, sacrifice a Swamp instead. If you do, put Lake of the Dead onto the battlefield. If you don't, put it into its owner's graveyard.
{T}: Add {B}.
{T}, Sacrifice a Swamp: Add {B}{B}{B}{B}.

Mox Amber

{T}: Add one mana of any color among legendary creatures and planeswalkers you control.

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Davriel, Rogue Shadowmage

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, Davriel, Rogue Shadowmage deals 2 damage to them.
−1: Target player discards a card.

Skirge Familiar

Rings of Brighthearth

Whenever you activate an ability, if it isn't a mana ability, you may pay {2}. If you do, copy that ability. You may choose new targets for the copy.

Oppression

Whenever a player casts a spell, that player discards a card.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Shrine of Limitless Power

At the beginning of your upkeep and whenever you cast a black spell, put a charge counter on Shrine of Limitless Power.
{4}, {T}, Sacrifice Shrine of Limitless Power: Target player discards a card for each charge counter on Shrine of Limitless Power.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Anvil of Bogardan

Players have no maximum hand size.
At the beginning of each player's draw step, that player draws an additional card, then discards a card.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Extraplanar Lens

Imprint — When Extraplanar Lens enters, you may exile target land you control.
Whenever a land with the same name as the exiled card is tapped for mana, its controller adds one mana of any type that land produced.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Jet Medallion

Black spells you cast cost {1} less to cast.

Nezumi Informant

When Nezumi Informant enters, each opponent discards a card.

Snow-Covered Swamp

Containment Construct

Whenever you discard a card, you may exile that card from your graveyard. If you do, you may play that card this turn.

Snuff Out

If you control a Swamp, you may pay 4 life rather than pay this spell's mana cost.
Destroy target nonblack creature. It can't be regenerated.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent of their choice that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Myojin of Night's Reach

Myojin of Night's Reach enters with a divinity counter on it if you cast it from your hand.
Myojin of Night's Reach has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Night's Reach: Each opponent discards their hand.

Caged Sun

As Caged Sun enters, choose a color.
Creatures you control of the chosen color get +1/+1.
Whenever a land's ability causes you to add one or more mana of the chosen color, add one additional mana of that color.

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Blood Pet

Sphinx-Bone Wand

Whenever you cast an instant or sorcery spell, you may put a charge counter on Sphinx-Bone Wand. If you do, Sphinx-Bone Wand deals damage equal to the number of charge counters on it to any target.

Deserted Temple

{T}: Add {C}.
{1}, {T}: Untap target land.

Scorched Ruins

If Scorched Ruins would enter, sacrifice two untapped lands instead. If you do, put Scorched Ruins onto the battlefield. If you don't, put it into its owner's graveyard.
{T}: Add {C}{C}{C}{C}.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Sedgemoor Witch

Menace
Ward—Pay 3 life. (Whenever this creature becomes the target of a spell or ability an opponent controls, counter it unless that player pays 3 life.)
Magecraft — Whenever you cast or copy an instant or sorcery spell, create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."