Go for the Throat

Mutilate

All creatures get -1/-1 until end of turn for each Swamp you control.

Tasha's Hideous Laughter

Each opponent exiles cards from the top of their library until that player has exiled cards with total mana value 20 or more.

Circu, Dimir Lobotomist

Whenever you cast a blue spell, exile the top card of target player's library.
Whenever you cast a black spell, exile the top card of target player's library.
Your opponents can't cast spells with the same name as a card exiled with Circu, Dimir Lobotomist.

Invoke Despair

Target opponent sacrifices a creature of their choice. If they can't, they lose 2 life and you draw a card. Then repeat this process for an enchantment and a planeswalker.

Counterspell

Baleful Strix

Flying, deathtouch
When Baleful Strix enters, draw a card.

Oona, Queen of the Fae

Flying
{X}{U/B}: Choose a color. Target opponent exiles the top X cards of their library. For each card of the chosen color exiled this way, create a 1/1 blue and black Faerie Rogue creature token with flying.

Hostage Taker

When Hostage Taker enters, exile another target creature or artifact until Hostage Taker leaves the battlefield. You may cast that card for as long as it remains exiled, and mana of any type can be spent to cast that spell.

Ashiok, Nightmare Muse

+1: Create a 2/3 blue and black Nightmare creature token with "Whenever this creature attacks or blocks, each opponent exiles the top two cards of their library."
−3: Return target nonland permanent to its owner's hand, then that player exiles a card from their hand.
−7: You may cast up to three spells from among face-up cards your opponents own from exile without paying their mana costs.