Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Whispersilk Cloak

Equipped creature can't be blocked and has shroud. (It can't be the target of spells or abilities.)
Equip {2}

Charcoal Diamond

Charcoal Diamond enters the battlefield tapped.
{T}: Add {B}.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature.
• Each opponent sacrifices a creature token.
• Each opponent sacrifices a planeswalker.

The Eldest Reborn

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Each opponent sacrifices a creature or planeswalker.
II — Each opponent discards a card.
III — Put target creature or planeswalker card from a graveyard onto the battlefield under your control.

Braids's Frightful Return

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — You may sacrifice a creature. If you do, each opponent discards a card.
II — Return target creature card from your graveyard to your hand.
III — Target opponent may sacrifice a nonland, nontoken permanent. If they don't, they lose 2 life and you draw a card.

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Blood Fountain

When Blood Fountain enters the battlefield, create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")
{3}{B}, {T}, Sacrifice Blood Fountain: Return up to two target creature cards from your graveyard to your hand.

Elvish Doomsayer

When Elvish Doomsayer dies, each opponent discards a card.

Dread Fugue

Cleave {2}{B} (You may cast this spell for its cleave cost. If you do, remove the words in square brackets.)
Target player reveals their hand. You choose a nonland card from it [with mana value 2 or less]. That player discards that card.

Sol Ring

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Bag of Holding

Whenever you discard a card, exile that card from your graveyard.
{2}, {T}: Draw a card, then discard a card.
{4}, {T}, Sacrifice Bag of Holding: Return all cards exiled with Bag of Holding to their owner's hand.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Predator's Gambit

Enchant creature
Enchanted creature gets +2/+1.
Enchanted creature has intimidate as long as its controller controls no other creatures. (It can't be blocked except by artifact creatures and/or creatures that share a color with it.)

Animus of Night's Reach

Menace (This creature can't be blocked except by two or more creatures.)
Whenever Animus of Night's Reach attacks, it gets +X/+0 until end of turn, where X is the number of creature cards in defending player's graveyard.

The Long Reach of Night

(As this Saga enters and after your draw step, add a lore counter.)
I, II — Each opponent sacrifices a creature unless they discard a card.
III — Exile this Saga, then return it to the battlefield transformed under your control.

The Long Reach of Night // Animus of Night's Reach

Cursed Flesh

Enchant creature
Enchanted creature gets -1/-1 and has fear. (It can't be blocked except by artifact creatures and/or black creatures.)

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Swamp

Gisa, Glorious Resurrector

If a creature an opponent controls would die, exile it instead.
At the beginning of your upkeep, put all creature cards exiled with Gisa, Glorious Resurrector onto the battlefield under your control. They gain decayed. (A creature with decayed can't block. When it attacks, sacrifice it at end of combat.)

Bone Shards

As an additional cost to cast this spell, sacrifice a creature or discard a card.
Destroy target creature or planeswalker.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature, then sacrifices a land.

Prickle Faeries

Flying
At the beginning of each opponent's upkeep, if that player has two or fewer cards in hand, Prickle Faeries deals 2 damage to them.

Have

Invasion of Eldraine

(As a Siege enters, choose an opponent to protect it. You and others can attack it. When it's defeated, exile it, then cast it transformed.)
When Invasion of Eldraine enters the battlefield, target opponent discards two cards.

Invasion of Eldraine // Prickle Faeries

Burglar Rat

When Burglar Rat enters the battlefield, each opponent discards a card.

Village Rites

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Go for the Throat

Bad Deal

You draw two cards and each opponent discards two cards. Each player loses 2 life.

Creeping Dread

At the beginning of your upkeep, each player discards a card. Each opponent who discarded a card that shares a card type with the card you discarded loses 3 life. (Players reveal the discarded cards simultaneously.)

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This creature can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Cloak of Confusion

Enchant creature you control
Whenever enchanted creature attacks and isn't blocked, you may have it assign no combat damage this turn. If you do, defending player discards a card at random.

Unnerve

Hymn to Tourach

Target player discards two cards at random.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Liliana's Specter

Flying
When Liliana's Specter enters the battlefield, each opponent discards a card.

Gruesome Deformity

Enchant creature
Enchanted creature has intimidate. (It can't be blocked except by artifact creatures and/or creatures that share a color with it.)

Virus Beetle

When Virus Beetle enters the battlefield, each opponent discards a card.

Rankle, Master of Pranks

Flying, haste
Whenever Rankle, Master of Pranks deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature.

Delirium Skeins

Mindslicer

When Mindslicer dies, each player discards their hand.

Myriad Landscape

Myriad Landscape enters the battlefield tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Cry of Contrition

Target player discards a card.
Haunt (When this spell card is put into a graveyard after resolving, exile it haunting target creature.)
When the creature Cry of Contrition haunts dies, target player discards a card.

Fell Specter

Flying
When Fell Specter enters the battlefield, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Mire in Misery

Each opponent sacrifices a creature or enchantment.

Nezumi Informant

When Nezumi Informant enters the battlefield, each opponent discards a card.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Sleeper's Guile

Enchant creature
Enchanted creature has fear. (It can't be blocked except by artifact creatures and/or black creatures.)
When Sleeper's Guile is put into a graveyard from the battlefield, return Sleeper's Guile to its owner's hand.

Sign in Blood

Target player draws two cards and loses 2 life.

Fleshbag Marauder

When Fleshbag Marauder enters the battlefield, each player sacrifices a creature.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Elderfang Disciple

When Elderfang Disciple enters the battlefield, each opponent discards a card.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Dark Ritual

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Black Cat

When Black Cat dies, target opponent discards a card at random.

Solemn Simulacrum

When Solemn Simulacrum enters the battlefield, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Divest

Target player reveals their hand. You choose an artifact or creature card from it. That player discards that card.

Plaguecrafter

When Plaguecrafter enters the battlefield, each player sacrifices a creature or planeswalker. Each player who can't discards a card.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Demon's Disciple

When Demon's Disciple enters the battlefield, each player sacrifices a creature or planeswalker.