Leyline of Punishment

If Leyline of Punishment is in your opening hand, you may begin the game with it on the battlefield.
Players can't gain life.
Damage can't be prevented.

Twinflame

Strive — This spell costs {2}{R} more to cast for each target beyond the first.
Choose any number of target creatures you control. For each of them, create a token that's a copy of that creature, except it has haste. Exile those tokens at the beginning of the next end step.

Big Score

As an additional cost to cast this spell, discard a card.
Draw two cards and create two Treasure tokens. (They're artifacts with "{T}, Sacrifice this artifact: Add one mana of any color.")

Field of Ruin

{T}: Add {C}.
{2}, {T}, Sacrifice Field of Ruin: Destroy target nonbasic land an opponent controls. Each player searches their library for a basic land card, puts it onto the battlefield, then shuffles.

Sulfuric Vortex

At the beginning of each player's upkeep, Sulfuric Vortex deals 2 damage to that player.
If a player would gain life, that player gains no life instead.

War's Toll

Whenever an opponent taps a land for mana, tap all lands that player controls.
If a creature an opponent controls attacks, all creatures that opponent controls attack if able.

Roiling Terrain

Destroy target land, then Roiling Terrain deals damage to that land's controller equal to the number of land cards in that player's graveyard.

Molten Rain

Destroy target land. If that land was nonbasic, Molten Rain deals 2 damage to the land's controller.

Grafted Exoskeleton

Equipped creature gets +2/+2 and has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever Grafted Exoskeleton becomes unattached from a permanent, sacrifice that permanent.
Equip {2}

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Ruination

Solemn Simulacrum

When Solemn Simulacrum enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Dingus Egg

Whenever a land is put into a graveyard from the battlefield, Dingus Egg deals 2 damage to that land's controller.

By Force

Tectonic Instability

Whenever a land enters, tap all lands its controller controls.

Wild Guess

As an additional cost to cast this spell, discard a card.
Draw two cards.

Dwarven Miner

{2}{R}, {T}: Destroy target nonbasic land.

Caged Sun

As Caged Sun enters, choose a color.
Creatures you control of the chosen color get +1/+1.
Whenever a land's ability causes you to add one or more mana of the chosen color, add one additional mana of that color.

Stoneshaker Shaman

At the beginning of each player's end step, that player sacrifices an untapped land.

Magus of the Moon

Wake of Destruction

Destroy target land and all other lands with the same name as that land.

Seething Song

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Mountain

Simian Spirit Guide

Exile Simian Spirit Guide from your hand: Add {R}.

Burnished Hart

{3}, Sacrifice Burnished Hart: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Wildfire

Each player sacrifices four lands. Wildfire deals 4 damage to each creature.

Impending Disaster

At the beginning of your upkeep, if there are seven or more lands on the battlefield, sacrifice Impending Disaster and destroy all lands.

Decree of Annihilation

Exile all artifacts, creatures, and lands from the battlefield, all cards from all graveyards, and all cards from all hands.
Cycling {5}{R}{R} ({5}{R}{R}, Discard this card: Draw a card.)
When you cycle Decree of Annihilation, destroy all lands.

Harsh Mentor

Whenever an opponent activates an ability of an artifact, creature, or land on the battlefield, if it isn't a mana ability, Harsh Mentor deals 2 damage to that player.

Manabarbs

Whenever a player taps a land for mana, Manabarbs deals 1 damage to that player.

Blood Sun

When Blood Sun enters, draw a card.
All lands lose all abilities except mana abilities.

Jokulhaups

Destroy all artifacts, creatures, and lands. They can't be regenerated.

Storm Cauldron

Each player may play an additional land during each of their turns.
Whenever a land is tapped for mana, return it to its owner's hand.

Ghost Quarter

{T}: Add {C}.
{T}, Sacrifice Ghost Quarter: Destroy target land. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Stone Rain

Coldsteel Heart

Coldsteel Heart enters tapped.
As Coldsteel Heart enters, choose a color.
{T}: Add one mana of the chosen color.

Sol Ring

Crawlspace

No more than two creatures can attack you each combat.

Thrill of Possibility

Defiler of Instinct

First strike
As an additional cost to cast red permanent spells, you may pay 2 life. Those spells cost {R} less to cast if you paid life this way. This effect reduces only the amount of red mana you pay.
Whenever you cast a red permanent spell, Defiler of Instinct deals 1 damage to any target.

Geomancer's Gambit

Destroy target land. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.
Draw a card.

Mogg Salvage

If an opponent controls an Island and you control a Mountain, you may cast this spell without paying its mana cost.
Destroy target artifact.

Heat Shimmer

Create a token that's a copy of target creature, except it has haste and "At the beginning of the end step, exile this permanent."

Mine Layer

{1}{R}, {T}: Put a mine counter on target land.
Whenever a land with a mine counter on it becomes tapped, destroy it.
When Mine Layer leaves the battlefield, remove all mine counters from all lands.

Doublecast

When you next cast an instant or sorcery spell this turn, copy that spell. You may choose new targets for the copy.

Desperate Ritual

Add {R}{R}{R}.
Splice onto Arcane {1}{R} (As you cast an Arcane spell, you may reveal this card from your hand and pay its splice cost. If you do, add this card's effects to that spell.)

Keldon Firebombers

When Keldon Firebombers enters, each player sacrifices all lands they control except for three.

Bust

Boom

Destroy target land you control and target land you don't control.

Boom // Bust

Smoke

Players can't untap more than one creature during their untap steps.

Palladium Myr

Moonsilver Key

{1}, {T}, Sacrifice Moonsilver Key: Search your library for an artifact card with a mana ability or a basic land card, reveal it, put it into your hand, then shuffle.

Invader Parasite

Imprint — When Invader Parasite enters, exile target land.
Whenever a land an opponent controls with the same name as the exiled card enters, Invader Parasite deals 2 damage to that player.

Bend or Break

Each player separates all nontoken lands they control into two piles. For each player, one of their piles is chosen by one of their opponents of their choice. Destroy all lands in the chosen piles. Tap all lands in the other piles.

Mana Geyser

Add {R} for each tapped land your opponents control.

Fire Diamond

Fire Diamond enters tapped.
{T}: Add {R}.

Demolish

Sol Talisman

Suspend 3—{1} (Rather than cast this card from your hand, pay {1} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
{T}: Add {C}{C}.

Heartless Hidetsugu

{T}: Heartless Hidetsugu deals damage to each player equal to half that player's life total, rounded down.

Thoughts of Ruin

Each player sacrifices a land for each card in your hand.

Anger of the Gods

Anger of the Gods deals 3 damage to each creature. If a creature dealt damage this way would die this turn, exile it instead.

Dualcaster Mage

Flash
When Dualcaster Mage enters, copy target instant or sorcery spell. You may choose new targets for the copy.

Raze

As an additional cost to cast this spell, sacrifice a land.
Destroy target land.

Darksteel Ingot

Indestructible (Effects that say "destroy" don't destroy this artifact.)
{T}: Add one mana of any color.

Zo-Zu the Punisher

Whenever a land enters, Zo-Zu the Punisher deals 2 damage to that land's controller.

God-Pharaoh's Statue

Spells your opponents cast cost {2} more to cast.
At the beginning of your end step, each opponent loses 1 life.

From the Ashes

Destroy all nonbasic lands. For each land destroyed this way, its controller may search their library for a basic land card and put it onto the battlefield. Then each player who searched their library this way shuffles.