Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Quag Sickness

Enchant creature
Enchanted creature gets -1/-1 for each Swamp you control.

Liliana's Mastery

Zombies you control get +1/+1.
When Liliana's Mastery enters, create two 2/2 black Zombie creature tokens.

Spread the Sickness

Destroy target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Kagemaro's Clutch

Enchant creature
Enchanted creature gets -X/-X, where X is the number of cards in your hand.

Engineered Plague

As Engineered Plague enters, choose a creature type.
All creatures of the chosen type get -1/-1.

Cartouche of Ambition

Enchant creature you control
When Cartouche of Ambition enters, you may put a -1/-1 counter on target creature.
Enchanted creature gets +1/+1 and has lifelink.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Erebos, Bleak-Hearted

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature.
Whenever another creature you control dies, you may pay 2 life. If you do, draw a card.
{1}{B}, Sacrifice another creature: Target creature gets -2/-1 until end of turn.

Sol Ring

Revel in Riches

Whenever a creature an opponent controls dies, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
At the beginning of your upkeep, if you control ten or more Treasures, you win the game.

Nyx Infusion

Enchant creature
Enchanted creature gets +2/+2 as long as it's an enchantment. Otherwise, it gets -2/-2.

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Skullclamp

Equipped creature gets +1/-1.
Whenever equipped creature dies, draw two cards.
Equip {1}

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Clutch of Undeath

Enchant creature
Enchanted creature gets +3/+3 as long as it's a Zombie. Otherwise, it gets -3/-3.

Incremental Blight

Put a -1/-1 counter on target creature, two -1/-1 counters on another target creature, and three -1/-1 counters on a third target creature.

Beseech the Queen

({2/B} can be paid with any two mana or with {B}. This card's mana value is 6.)
Search your library for a card with mana value less than or equal to the number of lands you control, reveal it, put it into your hand, then shuffle.

Carnifex Demon

Flying
Carnifex Demon enters with two -1/-1 counters on it.
{B}, Remove a -1/-1 counter from Carnifex Demon: Put a -1/-1 counter on each other creature.

Weight of the Underworld

Enchant creature
Enchanted creature gets -3/-2.

Curse of Death's Hold

Enchant player
Creatures enchanted player controls get -1/-1.

Soulstinger

When Soulstinger enters, put two -1/-1 counters on target creature you control.
When Soulstinger dies, you may put a -1/-1 counter on target creature for each -1/-1 counter on Soulstinger.

Liliana, Death Wielder

+2: Put a -1/-1 counter on up to one target creature.
−3: Destroy target creature with a -1/-1 counter on it.
−10: Return all creature cards from your graveyard to the battlefield.

Fevered Convulsions

{2}{B}{B}: Put a -1/-1 counter on target creature.

Core Prowler

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Core Prowler dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Phyrexian Boon

Enchant creature
Enchanted creature gets +2/+1 as long as it's black. Otherwise, it gets -1/-2.

Necropede

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Necropede dies, you may put a -1/-1 counter on target creature.

Inner Demon

Enchant creature
Enchanted creature gets +2/+2, has flying, and is a Demon in addition to its other types.
When Inner Demon enters, all non-Demon creatures get -2/-2 until end of turn.

Dictate of Erebos

Flash
Whenever a creature you control dies, each opponent sacrifices a creature.

Fume Spitter

Sacrifice Fume Spitter: Put a -1/-1 counter on target creature.

Cabal Stronghold

{T}: Add {C}.
{3}, {T}: Add {B} for each basic Swamp you control.

Planeswalker's Scorn

{3}{B}: Target opponent reveals a card at random from their hand. Target creature gets -X/-X until end of turn, where X is the revealed card's mana value. Activate only as a sorcery.

Black Sun's Zenith

Put X -1/-1 counters on each creature. Shuffle Black Sun's Zenith into its owner's library.

Night of Souls' Betrayal

Corrosive Mentor

Black creatures you control have wither. (They deal damage to creatures in the form of -1/-1 counters.)

Damnation

Destroy all creatures. They can't be regenerated.

Necroskitter

Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever a creature an opponent controls with a -1/-1 counter on it dies, you may return that card to the battlefield under your control.

Virulent Plague

Karn's Bastion

{T}: Add {C}.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Archfiend of Ifnir

Flying
Whenever you cycle or discard another card, put a -1/-1 counter on each creature your opponents control.
Cycling {2} ({2}, Discard this card: Draw a card.)

Massacre Girl

Menace
When Massacre Girl enters, each other creature gets -1/-1 until end of turn. Whenever a creature dies this turn, each creature other than Massacre Girl gets -1/-1 until end of turn.

Grim Poppet

Grim Poppet enters with three -1/-1 counters on it.
Remove a -1/-1 counter from Grim Poppet: Put a -1/-1 counter on another target creature.

Demonic Tutor

Liliana's Influence

Put a -1/-1 counter on each creature you don't control. You may search your library and/or graveyard for a card named Liliana, Death Wielder, reveal it, and put it into your hand. If you search your library this way, shuffle.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Doomwake Giant

Constellation — Whenever Doomwake Giant or another enchantment you control enters, creatures your opponents control get -1/-1 until end of turn.

Black Market

Whenever a creature dies, put a charge counter on Black Market.
At the beginning of your first main phase, add {B} for each charge counter on Black Market.

Midnight Banshee

Wither (This deals damage to creatures in the form of -1/-1 counters.)
At the beginning of your upkeep, put a -1/-1 counter on each nonblack creature.

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Banewhip Punisher

When Banewhip Punisher enters, you may put a -1/-1 counter on target creature.
{B}, Sacrifice Banewhip Punisher: Destroy target creature that has a -1/-1 counter on it.

Nest of Scarabs

Whenever you put one or more -1/-1 counters on a creature, create that many 1/1 black Insect creature tokens.

Desert of the Glorified

Desert of the Glorified enters tapped.
{T}: Add {B}.
Cycling {1}{B} ({1}{B}, Discard this card: Draw a card.)

Glistening Oil

Enchant creature
Enchanted creature has infect.
At the beginning of your upkeep, put a -1/-1 counter on enchanted creature.
When Glistening Oil is put into a graveyard from the battlefield, return Glistening Oil to its owner's hand.

Traveling Plague

Enchant creature
At the beginning of each upkeep, put a plague counter on Traveling Plague.
Enchanted creature gets -1/-1 for each plague counter on Traveling Plague.
When enchanted creature leaves the battlefield, that creature's controller returns Traveling Plague from its owner's graveyard to the battlefield.

Maggot Therapy

Flash
Enchant creature
Enchanted creature gets +2/-2.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Liliana, Dreadhorde General

Whenever a creature you control dies, draw a card.
+1: Create a 2/2 black Zombie creature token.
−4: Each player sacrifices two creatures.
−9: Each opponent chooses a permanent they control of each permanent type and sacrifices the rest.

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Soul Snuffers

When Soul Snuffers enters, put a -1/-1 counter on each creature.

Sadistic Obsession

Enchant creature
Enchanted creature has "{B}, {T}: Put a -1/-1 counter on target creature."

Swamp

Torture

Enchant creature
{1}{B}: Put a -1/-1 counter on enchanted creature.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Screams from Within

Enchant creature
Enchanted creature gets -1/-1.
When enchanted creature dies, return Screams from Within from your graveyard to the battlefield.

Hero's Downfall

Blowfly Infestation

Whenever a creature dies, if it had a -1/-1 counter on it, put a -1/-1 counter on target creature.

Sudden Spoiling

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Until end of turn, creatures target player controls lose all abilities and have base power and toughness 0/2.