Mindslicer

When Mindslicer dies, each player discards their hand.

Nezumi Informant

When Nezumi Informant enters the battlefield, each opponent discards a card.

Demonfire

Demonfire deals X damage to any target. If a creature dealt damage this way would die this turn, exile it instead.
Hellbent — If you have no cards in hand, this spell can't be countered and the damage can't be prevented.

Charcoal Diamond

Charcoal Diamond enters the battlefield tapped.
{T}: Add {B}.

Dark Suspicions

At the beginning of each opponent's upkeep, that player loses X life, where X is the number of cards in that player's hand minus the number of cards in your hand.

Fire Diamond

Fire Diamond enters the battlefield tapped.
{T}: Add {R}.

Liliana, Waker of the Dead

+1: Each player discards a card. Each opponent who can't loses 3 life.
−3: Target creature gets -X/-X until end of turn, where X is the number of cards in your graveyard.
−7: You get an emblem with "At the beginning of combat on your turn, put target creature card from a graveyard onto the battlefield under your control. It gains haste."

The Rack

As The Rack enters the battlefield, choose an opponent.
At the beginning of the chosen player's upkeep, The Rack deals X damage to that player, where X is 3 minus the number of cards in their hand.

Elderfang Disciple

When Elderfang Disciple enters the battlefield, each opponent discards a card.

Mindstorm Crown

At the beginning of your upkeep, draw a card if you had no cards in hand at the beginning of this turn. If you had a card in hand, Mindstorm Crown deals 1 damage to you.

Angrath, the Flame-Chained

+1: Each opponent discards a card and loses 2 life.
−3: Gain control of target creature until end of turn. Untap it. It gains haste until end of turn. Sacrifice it at the beginning of the next end step if it has mana value 3 or less.
−8: Each opponent loses life equal to the number of cards in their graveyard.

Avaricious Dragon

Flying
At the beginning of your draw step, draw an additional card.
At the beginning of your end step, discard your hand.

Nightmare Unmaking

Choose one —
• Exile each creature with power greater than the number of cards in your hand.
• Exile each creature with power less than the number of cards in your hand.

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Gibbering Descent

At the beginning of each player's upkeep, that player loses 1 life and discards a card.
Hellbent — Skip your upkeep step if you have no cards in hand.
Madness {2}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

One with Nothing

Twinstrike

Twinstrike deals 2 damage to each of two target creatures.
Hellbent — Destroy those creatures instead if you have no cards in hand.

Hellfire Mongrel

At the beginning of each opponent's upkeep, if that player has two or fewer cards in hand, Hellfire Mongrel deals 2 damage to that player.

Fiery Temper

Fiery Temper deals 3 damage to any target.
Madness {R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Sol Ring

Grim Strider

Grim Strider gets -1/-1 for each card in your hand.

Terminal Agony

Destroy target creature.
Madness {B}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Howltooth Hollow

Hideaway 4 (When this land enters the battlefield, look at the top four cards of your library, exile one face down, then put the rest on the bottom in a random order.)
Howltooth Hollow enters the battlefield tapped.
{T}: Add {B}.
{B}, {T}: You may play the exiled card without paying its mana cost if each player has no cards in hand.

Burglar Rat

When Burglar Rat enters the battlefield, each opponent discards a card.

Tragic Fall

Target creature gets -3/-3 until end of turn.
Hellbent — That creature gets -13/-13 until end of turn instead if you have no cards in hand.

Rix Maadi, Dungeon Palace

{T}: Add {C}.
{1}{B}{R}, {T}: Each player discards a card. Activate only as a sorcery.

Corpse Explosion

As an additional cost to cast this spell, exile a creature card from your graveyard.
Corpse Explosion deals damage equal to the exiled card's power to each creature and each planeswalker.

Liliana of the Veil

+1: Each player discards a card.
−2: Target player sacrifices a creature.
−6: Separate all permanents target player controls into two piles. That player sacrifices all permanents in the pile of their choice.

Words of Waste

{1}: The next time you would draw a card this turn, each opponent discards a card instead.

Malfegor

Flying
When Malfegor enters the battlefield, discard your hand. Each opponent sacrifices a creature for each card discarded this way.

Prickle Faeries

Flying
At the beginning of each opponent's upkeep, if that player has two or fewer cards in hand, Prickle Faeries deals 2 damage to them.

Invasion of Eldraine

(As a Siege enters, choose an opponent to protect it. You and others can attack it. When it's defeated, exile it, then cast it transformed.)
When Invasion of Eldraine enters the battlefield, target opponent discards two cards.

Invasion of Eldraine // Prickle Faeries

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Paupers' Cage

At the beginning of each opponent's upkeep, if that player has two or fewer cards in hand, Paupers' Cage deals 2 damage to that player.

Thought Gorger

Trample
When Thought Gorger enters the battlefield, put a +1/+1 counter on it for each card in your hand. If you do, discard your hand.
When Thought Gorger leaves the battlefield, draw a card for each +1/+1 counter on it.

Sire of Insanity

At the beginning of each end step, each player discards their hand.

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Ill-Gotten Gains

Exile Ill-Gotten Gains. Each player discards their hand, then returns up to three cards from their graveyard to their hand.

Dread Slag

Trample
Dread Slag gets -4/-4 for each card in your hand.

Behold the Beyond

Discard your hand. Search your library for three cards, put them into your hand, then shuffle.

Neheb, the Worthy

First strike
Other Minotaurs you control have first strike.
As long as you have one or fewer cards in hand, Minotaurs you control get +2/+0.
Whenever Neheb, the Worthy deals combat damage to a player, each player discards a card.

Ensnaring Bridge

Creatures with power greater than the number of cards in your hand can't attack.

Dark Withering

Destroy target nonblack creature.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Virus Beetle

When Virus Beetle enters the battlefield, each opponent discards a card.

Fell Specter

Flying
When Fell Specter enters the battlefield, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Keldon Megaliths

Keldon Megaliths enters the battlefield tapped.
{T}: Add {R}.
Hellbent — {1}{R}, {T}: Keldon Megaliths deals 1 damage to any target. Activate only if you have no cards in hand.

Lavaborn Muse

At the beginning of each opponent's upkeep, if that player has two or fewer cards in hand, Lavaborn Muse deals 3 damage to that player.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Chainer, Nightmare Adept

Discard a card: You may cast a creature spell from your graveyard this turn. Activate only once each turn.
Whenever a nontoken creature enters the battlefield under your control, if you didn't cast it from your hand, it gains haste until your next turn.

Jagged Poppet

Whenever Jagged Poppet is dealt damage, discard that many cards.
Hellbent — Whenever Jagged Poppet deals combat damage to a player, if you have no cards in hand, that player discards cards equal to the damage.

Hollowborn Barghest

At the beginning of your upkeep, if you have no cards in hand, each opponent loses 2 life.
At the beginning of each opponent's upkeep, if that player has no cards in hand, they lose 2 life.

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Kardur's Vicious Return

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — You may sacrifice a creature. When you do, Kardur's Vicious Return deals 3 damage to any target.
II — Each player discards a card.
III — Return target creature card from your graveyard to the battlefield. Put a +1/+1 counter on it. It gains haste until your next turn.

Feast of Sanity

Whenever you discard a card, Feast of Sanity deals 1 damage to any target and you gain 1 life.

Davriel, Rogue Shadowmage

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, Davriel, Rogue Shadowmage deals 2 damage to them.
−1: Target player discards a card.

Viseling

At the beginning of each opponent's upkeep, Viseling deals X damage to that player, where X is the number of cards in their hand minus 4.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Scalding Tongs

At the beginning of your upkeep, if you have three or fewer cards in hand, Scalding Tongs deals 1 damage to target opponent or planeswalker.

Delirium Skeins

Solphim, Mayhem Dominus

If a source you control would deal noncombat damage to an opponent or a permanent an opponent controls, it deals double that damage to that player or permanent instead.
{1}{R/P}{R/P}, Discard two cards: Put an indestructible counter on Solphim, Mayhem Dominus. ({R/P} can be paid with either {R} or 2 life.)

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Headless Specter

Flying
Hellbent — Whenever Headless Specter deals combat damage to a player, if you have no cards in hand, that player discards a card at random.

Arcane Signet

Rackling

At the beginning of each opponent's upkeep, Rackling deals X damage to that player, where X is 3 minus the number of cards in their hand.

Chandra, Heart of Fire

+1: Discard your hand, then exile the top three cards of your library. Until end of turn, you may play cards exiled this way.
+1: Chandra, Heart of Fire deals 2 damage to any target.
−9: Search your graveyard and library for any number of red instant and/or sorcery cards, exile them, then shuffle. You may cast them this turn. Add six {R}.

Anthem of Rakdos

Whenever a creature you control attacks, it gets +2/+0 until end of turn and Anthem of Rakdos deals 1 damage to you.
Hellbent — As long as you have no cards in hand, if a source you control would deal damage to a permanent or player, it deals double that damage to that permanent or player instead.

Hazoret the Fervent

Indestructible, haste
Hazoret the Fervent can't attack or block unless you have one or fewer cards in hand.
{2}{R}, Discard a card: Hazoret deals 2 damage to each opponent.

Kroxa, Titan of Death's Hunger

When Kroxa enters the battlefield, sacrifice it unless it escaped.
Whenever Kroxa enters the battlefield or attacks, each opponent discards a card, then each opponent who didn't discard a nonland card this way loses 3 life.
Escape—{B}{B}{R}{R}, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Creeping Dread

At the beginning of your upkeep, each player discards a card. Each opponent who discarded a card that shares a card type with the card you discarded loses 3 life. (Players reveal the discarded cards simultaneously.)

Dream Devourer

Each nonland card in your hand without foretell has foretell. Its foretell cost is equal to its mana cost reduced by {2}. (During your turn, you may pay {2} and exile it from your hand face down. Cast it on a later turn for its foretell cost.)
Whenever you foretell a card, Dream Devourer gets +2/+0 until end of turn.

Null Brooch

{2}, {T}, Discard your hand: Counter target noncreature spell.

Stabwhisker the Odious

At the beginning of each opponent's upkeep, that player loses 1 life for each card fewer than three in their hand.

Nezumi Shortfang

{1}{B}, {T}: Target opponent discards a card. Then if that player has no cards in hand, flip Nezumi Shortfang.

Nezumi Shortfang // Stabwhisker the Odious

Ghirapur Orrery

Each player may play an additional land on each of their turns.
At the beginning of each player's upkeep, if that player has no cards in hand, that player draws three cards.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Stronghold Rats

Shadow (This creature can block or be blocked by only creatures with shadow.)
Whenever Stronghold Rats deals combat damage to a player, each player discards a card.

Swamp

Pain Magnification

Whenever an opponent is dealt 3 or more damage by a single source, that player discards a card.