Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Contagious Nim

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Bone Splinters

As an additional cost to cast this spell, sacrifice a creature.
Destroy target creature.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.

Skinrender

When Skinrender enters, put three -1/-1 counters on target creature.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Life's Finale

Destroy all creatures, then search target opponent's library for up to three creature cards and put them into their graveyard. Then that player shuffles.

Phyrexian Atlas

{T}: Add one mana of any color.
Corrupted — Whenever Phyrexian Atlas becomes tapped, each opponent who has three or more poison counters loses 1 life.

Offer Immortality

Target creature gains deathtouch and indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Memoricide

Choose a nonland card name. Search target player's graveyard, hand, and library for any number of cards with that name and exile them. Then that player shuffles.

Decimator Web

{4}, {T}: Target opponent loses 2 life, gets a poison counter, then mills six cards.

Plague Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{T}: Add {C}.

Vault of Whispers

Chancellor of the Dross

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent loses 3 life, then you gain life equal to the life lost this way.
Flying, lifelink

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Flesh-Eater Imp

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Sacrifice a creature: Flesh-Eater Imp gets +1/+1 until end of turn.

Vraan, Executioner Thane

Whenever one or more other creatures you control die, each opponent loses 2 life and you gain 2 life. This ability triggers only once each turn.

Caustic Hound

When Caustic Hound dies, each player loses 4 life.

Vat Emergence

Put target creature card from a graveyard onto the battlefield under your control. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Phyresis

Enchant creature
Enchanted creature has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Spread the Sickness

Destroy target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Gulping Scraptrap

When Gulping Scraptrap enters or dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Skithiryx, the Blight Dragon

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx, the Blight Dragon gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

Mortis Dogs

Whenever Mortis Dogs attacks, it gets +2/+0 until end of turn.
When Mortis Dogs dies, target player loses life equal to its power.

Glistening Oil

Enchant creature
Enchanted creature has infect.
At the beginning of your upkeep, put a -1/-1 counter on enchanted creature.
When Glistening Oil is put into a graveyard from the battlefield, return Glistening Oil to its owner's hand.

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Breach the Multiverse

Each player mills ten cards. For each player, choose a creature or planeswalker card in that player's graveyard. Put those cards onto the battlefield under your control. Then each creature you control becomes a Phyrexian in addition to its other types.

Phyrexian Crusader

First strike, protection from red and from white
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Swamp

Reaper of Sheoldred

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever a source deals damage to Reaper of Sheoldred, that source's controller gets a poison counter.

Merciless Repurposing

Exile target creature. Incubate 3. (Create an Incubator token with three +1/+1 counters on it and "{2}: Transform this artifact." It transforms into a 0/0 Phyrexian artifact creature.)

Zenith Chronicler

Whenever a player casts their first multicolored spell each turn, each other player draws a card.

Despise

Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.

Septic Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever Septic Rats attacks, if defending player is poisoned, it gets +1/+1 until end of turn.

Hand of the Praetors

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Other creatures you control with infect get +1/+1.
Whenever you cast a creature spell with infect, target player gets a poison counter.

Nested Ghoul

Whenever a source deals damage to Nested Ghoul, create a 2/2 black Phyrexian Zombie creature token.

Carnifex Demon

Flying
Carnifex Demon enters with two -1/-1 counters on it.
{B}, Remove a -1/-1 counter from Carnifex Demon: Put a -1/-1 counter on each other creature.

Necrotic Ooze

As long as Necrotic Ooze is on the battlefield, it has all activated abilities of all creature cards in all graveyards.

Blistergrub

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
When Blistergrub dies, each opponent loses 2 life.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Gruesome Encore

Put target creature card from an opponent's graveyard onto the battlefield under your control. It gains haste. Exile it at the beginning of the next end step. If that creature would leave the battlefield, exile it instead of putting it anywhere else.

Mirrorworks

Whenever another nontoken artifact you control enters, you may pay {2}. If you do, create a token that's a copy of that artifact.

Tainted Strike

Target creature gets +1/+0 and gains infect until end of turn. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Fume Spitter

Sacrifice Fume Spitter: Put a -1/-1 counter on target creature.

Drivnod, Carnage Dominus

If a creature dying causes a triggered ability of a permanent you control to trigger, that ability triggers an additional time.
{B/P}{B/P}, Exile three creature cards from your graveyard: Put an indestructible counter on Drivnod, Carnage Dominus. ({B/P} can be paid with either {B} or 2 life.)

Phyrexian Vatmother

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
At the beginning of your upkeep, you get a poison counter.

Geth's Verdict

Target player sacrifices a creature of their choice and loses 1 life.

Black Sun's Twilight

Up to one target creature gets -X/-X until end of turn. If X is 5 or more, return a creature card with mana value X or less from your graveyard to the battlefield tapped.

Terror of Towashi

Deathtouch
Whenever Terror of Towashi attacks, you may pay {3}{B}. When you do, return target creature card from your graveyard to the battlefield. It's a Phyrexian in addition to its other types.

Batterskull

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +4/+4 and has vigilance and lifelink.
{3}: Return Batterskull to its owner's hand.
Equip {5}

Evolved Sleeper

{B}: Evolved Sleeper becomes a Human Cleric with base power and toughness 2/2.
{1}{B}: If Evolved Sleeper is a Cleric, put a deathtouch counter on it and it becomes a Phyrexian Human Cleric with base power and toughness 3/3.
{1}{B}{B}: If Evolved Sleeper is a Phyrexian, put a +1/+1 counter on it, then you draw a card and you lose 1 life.

Massacre Wurm

When this creature enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Toxic Nim

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Regenerate Toxic Nim.

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Go for the Throat

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Isolation Cell

Whenever an opponent casts a creature spell, that player loses 2 life unless they pay {2}.

Horrifying Revelation

Target player discards a card, then mills a card.

Dross Skullbomb

{1}, Sacrifice Dross Skullbomb: Draw a card.
{2}{B}, Sacrifice Dross Skullbomb: Return target creature card from your graveyard to your hand. Draw a card. Activate only as a sorcery.

The Dross Pits

The Dross Pits enters tapped.
{T}: Add {B}.
{1}{B}, {T}, Sacrifice The Dross Pits: Draw a card.

Caress of Phyrexia

Target player draws three cards, loses 3 life, and gets three poison counters.

Core Prowler

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Core Prowler dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Annihilating Glare

As an additional cost to cast this spell, pay {4} or sacrifice an artifact or creature.
Destroy target creature or planeswalker.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Cut Down

Destroy target creature with total power and toughness 5 or less.

Drown in Ichor

Target creature gets -4/-4 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Virulent Wound

Put a -1/-1 counter on target creature. When that creature dies this turn, its controller gets a poison counter.

Karumonix, the Rat King

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Other Rats you control have toxic 1.
When Karumonix enters, look at the top five cards of your library. You may reveal any number of Rat cards from among them and put the revealed cards into your hand. Put the rest on the bottom of your library in a random order.

Phyrexian Obliterator

Trample
Whenever a source deals damage to Phyrexian Obliterator, that source's controller sacrifices that many permanents of their choice.

Vault Skirge

({B/P} can be paid with either {B} or 2 life.)
Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Perilous Myr

When Perilous Myr dies, it deals 2 damage to any target.

Anoint with Affliction

Exile target creature if it has mana value 3 or less.
Corrupted — Exile that creature instead if its controller has three or more poison counters.

Seer of Stolen Sight

Menace (This creature can't be blocked except by two or more creatures.)
Whenever one or more artifacts and/or creatures you control are put into a graveyard from the battlefield, surveil 1. (Look at the top card of your library. You may put that card into your graveyard.)

Geth, Lord of the Vault

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
{X}{B}: Put target artifact or creature card with mana value X from an opponent's graveyard onto the battlefield under your control tapped. Then that player mills X cards.

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters, each player gets a poison counter.

Whispering Specter

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever Whispering Specter deals combat damage to a player, you may sacrifice it. If you do, that player discards a card for each poison counter they have.

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Grafted Butcher

When Grafted Butcher enters, Phyrexians you control gain menace until end of turn.
Other Phyrexians you control get +1/+1.
{3}{B}, Sacrifice an artifact or creature: Return Grafted Butcher from your graveyard to the battlefield. Activate only as a sorcery.

Flensermite

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Blightbelly Rat

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Blightbelly Rat dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Kinzu of the Bleak Coven

Flying
Whenever another nontoken creature you control dies, you may pay 2 life and exile it. If you do, create a token that's a copy of that creature, except it's 1/1 and has toxic 1. (Players dealt combat damage by it also get a poison counter.)

Necrogen Communion

Enchant creature you control
Enchanted creature has toxic 2. (Players dealt combat damage by it also get two poison counters.)
When enchanted creature dies, return that card to the battlefield under your control.

Shrine of Limitless Power

At the beginning of your upkeep and whenever you cast a black spell, put a charge counter on Shrine of Limitless Power.
{4}, {T}, Sacrifice Shrine of Limitless Power: Target player discards a card for each charge counter on Shrine of Limitless Power.

Blind Zealot

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
Whenever Blind Zealot deals combat damage to a player, you may sacrifice it. If you do, destroy target creature that player controls.

Praetor's Grasp

Search target opponent's library for a card and exile it face down. Then that player shuffles. You may play that card for as long as it remains exiled.

Trigon of Corruption

Trigon of Corruption enters with three charge counters on it.
{B}{B}, {T}: Put a charge counter on Trigon of Corruption.
{2}, {T}, Remove a charge counter from Trigon of Corruption: Put a -1/-1 counter on target creature.

Wurmcoil Engine

Deathtouch, lifelink
When Wurmcoil Engine dies, create a 3/3 colorless Phyrexian Wurm artifact creature token with deathtouch and a 3/3 colorless Phyrexian Wurm artifact creature token with lifelink.

Black Sun's Zenith

Put X -1/-1 counters on each creature. Shuffle Black Sun's Zenith into its owner's library.

Bilious Skulldweller

Deathtouch
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Enslave

Enchant creature
You control enchanted creature.
At the beginning of your upkeep, enchanted creature deals 1 damage to its owner.