Angrath, the Flame-Chained

+1: Each opponent discards a card and loses 2 life.
−3: Gain control of target creature until end of turn. Untap it. It gains haste until end of turn. Sacrifice it at the beginning of the next end step if it has mana value 3 or less.
−8: Each opponent loses life equal to the number of cards in their graveyard.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Kroxa, Titan of Death's Hunger

When Kroxa enters, sacrifice it unless it escaped.
Whenever Kroxa enters or attacks, each opponent discards a card, then each opponent who didn't discard a nonland card this way loses 3 life.
Escape—{B}{B}{R}{R}, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Herald of Anguish

Improvise (Your artifacts can help cast this spell. Each artifact you tap after you're done activating mana abilities pays for {1}.)
Flying
At the beginning of your end step, each opponent discards a card.
{1}{B}, Sacrifice an artifact: Target creature gets -2/-2 until end of turn.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Unnerve

Abyssal Nocturnus

Whenever an opponent discards a card, Abyssal Nocturnus gets +2/+2 and gains fear until end of turn. (It can't be blocked except by artifact creatures and/or black creatures.)

Burglar Rat

When Burglar Rat enters, each opponent discards a card.

Worldgorger Dragon

Flying, trample
When Worldgorger Dragon enters, exile all other permanents you control.
When Worldgorger Dragon leaves the battlefield, return the exiled cards to the battlefield under their owners' control.

Myojin of Night's Reach

Myojin of Night's Reach enters with a divinity counter on it if you cast it from your hand.
Myojin of Night's Reach has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Night's Reach: Each opponent discards their hand.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

The Eldest Reborn

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Each opponent sacrifices a creature or planeswalker of their choice.
II — Each opponent discards a card.
III — Put target creature or planeswalker card from a graveyard onto the battlefield under your control.

Entomb

Search your library for a card, put that card into your graveyard, then shuffle.

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Animate Dead

Enchant creature card in a graveyard
When Animate Dead enters, if it's on the battlefield, it loses "enchant creature card in a graveyard" and gains "enchant creature put onto the battlefield with Animate Dead." Return enchanted creature card to the battlefield under your control and attach Animate Dead to it. When Animate Dead leaves the battlefield, that creature's controller sacrifices it.
Enchanted creature gets -1/-0.

Awaken the Erstwhile

Each player discards all the cards in their hand, then creates that many 2/2 black Zombie creature tokens.

Distended Mindbender

Emerge {5}{B}{B} (You may cast this spell by sacrificing a creature and paying the emerge cost reduced by that creature's mana value.)
When you cast this spell, target opponent reveals their hand. You choose from it a nonland card with mana value 3 or less and a card with mana value 4 or greater. That player discards those cards.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Buried Alive

Search your library for up to three creature cards, put them into your graveyard, then shuffle.

Dance of the Dead

Enchant creature card in a graveyard
When Dance of the Dead enters, if it's on the battlefield, it loses "enchant creature card in a graveyard" and gains "enchant creature put onto the battlefield with Dance of the Dead." Put enchanted creature card onto the battlefield tapped under your control and attach Dance of the Dead to it. When Dance of the Dead leaves the battlefield, that creature's controller sacrifices it.
Enchanted creature gets +1/+1 and doesn't untap during its controller's untap step.
At the beginning of the upkeep of enchanted creature's controller, that player may pay {1}{B}. If the player does, untap that creature.

Sire of Insanity

At the beginning of each end step, each player discards their hand.

Thought Distortion

This spell can't be countered.
Target opponent reveals their hand. Exile all noncreature, nonland cards from that player's hand and graveyard.

Tasigur's Cruelty

Delve (Each card you exile from your graveyard while casting this spell pays for {1}.)
Each opponent discards two cards.