Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Accomplished Alchemist

{T}: Add one mana of any color.
{T}: Add X mana of any one color, where X is the amount of life you gained this turn.

Adanto Vanguard

As long as Adanto Vanguard is attacking, it gets +2/+0.
Pay 4 life: Adanto Vanguard gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Beledros Witherbloom

Flying
At the beginning of each upkeep, create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."
Pay 10 life: Untap all lands you control. Activate only once each turn.

Mana Crypt

At the beginning of your upkeep, flip a coin. If you lose the flip, Mana Crypt deals 3 damage to you.
{T}: Add {C}{C}.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Windswept Heath

{T}, Pay 1 life, Sacrifice Windswept Heath: Search your library for a Forest or Plains card, put it onto the battlefield, then shuffle.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Greven, Predator Captain

Menace
Greven, Predator Captain gets +X/+0, where X is the amount of life you've lost this turn.
Whenever Greven attacks, you may sacrifice another creature. If you do, you draw cards equal to that creature's power and you lose life equal to that creature's toughness.

Treasonous Ogre

Dethrone (Whenever this creature attacks the player with the most life or tied for most life, put a +1/+1 counter on it.)
Pay 3 life: Add {R}.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Reflecting Pool

{T}: Add one mana of any type that a land you control could produce.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Wooded Foothills

{T}, Pay 1 life, Sacrifice Wooded Foothills: Search your library for a Mountain or Forest card, put it onto the battlefield, then shuffle.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Snow-Covered Swamp

Congregate

Target player gains 2 life for each creature on the battlefield.

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Bayou

Painful Truths

Converge — You draw X cards and you lose X life, where X is the number of colors of mana spent to cast this spell.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Mischievous Poltergeist

Flying
Pay 1 life: Regenerate Mischievous Poltergeist.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Ikra Shidiqi, the Usurper

Menace
Whenever a creature you control deals combat damage to a player, you gain life equal to that creature's toughness.
Partner (You can have two commanders if both have partner.)

Solitude

Flash
Lifelink
When Solitude enters, exile up to one other target creature. That creature's controller gains life equal to its power.
Evoke—Exile a white card from your hand.

Snow-Covered Forest

Stinging Study

You draw X cards and you lose X life, where X is the mana value of a commander you own on the battlefield or in the command zone.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is Esper Sentinel's power.

Grim Feast

At the beginning of your upkeep, Grim Feast deals 1 damage to you.
Whenever a creature is put into an opponent's graveyard from the battlefield, you gain life equal to its toughness.

Temple of Aclazotz

(Transforms from Arguel's Blood Fast.)
{T}: Add {B}.
{T}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Arguel's Blood Fast

{1}{B}, Pay 2 life: Draw a card.
At the beginning of your upkeep, if you have 5 or less life, you may transform Arguel's Blood Fast.

Arguel's Blood Fast // Temple of Aclazotz

Fellwar Stone

Scrubland

Heliod, Sun-Crowned

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature.
Whenever you gain life, put a +1/+1 counter on target creature or enchantment you control.
{1}{W}: Another target creature gains lifelink until end of turn.

Savannah

Healing Technique

Demonstrate (When you cast this spell, you may copy it. If you do, choose an opponent to also copy it. Players may choose new targets for their copies.)
Return target card from your graveyard to your hand. You gain life equal to that card's mana value. Exile Healing Technique.

Bountiful Promenade

Bountiful Promenade enters tapped unless you have two or more opponents.
{T}: Add {G} or {W}.

Lorcan, Warlock Collector

Flying
Whenever a creature card is put into an opponent's graveyard from anywhere, you may pay life equal to its mana value. If you do, put it onto the battlefield under your control. It's a Warlock in addition to its other types.
If a Warlock you control would die, exile it instead.

Tymna the Weaver

Lifelink
At the beginning of each of your postcombat main phases, you may pay X life, where X is the number of opponents that were dealt combat damage this turn. If you do, draw X cards.
Partner (You can have two commanders if both have partner.)

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature of their choice and you return up to one target creature card from your graveyard to your hand.

Stomping Ground

({T}: Add {R} or {G}.)
As Stomping Ground enters, you may pay 2 life. If you don't, it enters tapped.

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Valakut Stoneforge

Valakut Stoneforge enters tapped.
{T}: Add {R}.

Valakut Awakening

Put any number of cards from your hand on the bottom of your library, then draw that many cards plus one.

Valakut Awakening // Valakut Stoneforge

Taiga

Hatred

As an additional cost to cast this spell, pay X life.
Target creature gets +X/+0 until end of turn.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Mythos of Nethroi

Destroy target nonland permanent if it's a creature or if {G}{W} was spent to cast this spell.

Temple Garden

({T}: Add {G} or {W}.)
As Temple Garden enters, you may pay 2 life. If you don't, it enters tapped.

Indatha Triome

({T}: Add {W}, {B}, or {G}.)
Indatha Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Bala Ged Sanctuary

Bala Ged Sanctuary enters tapped.
{T}: Add {G}.

Bala Ged Recovery

Return target card from your graveyard to your hand.

Bala Ged Recovery // Bala Ged Sanctuary

Spectator Seating

Spectator Seating enters tapped unless you have two or more opponents.
{T}: Add {R} or {W}.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Farseek

Search your library for a Plains, Island, Swamp, or Mountain card, put it onto the battlefield tapped, then shuffle.

Verdant Catacombs

{T}, Pay 1 life, Sacrifice Verdant Catacombs: Search your library for a Swamp or Forest card, put it onto the battlefield, then shuffle.

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Sacred Foundry

({T}: Add {R} or {W}.)
As Sacred Foundry enters, you may pay 2 life. If you don't, it enters tapped.

Resolute Archangel

Flying
When Resolute Archangel enters, if your life total is less than your starting life total, it becomes equal to your starting life total.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Snow-Covered Mountain

Overgrown Tomb

({T}: Add {B} or {G}.)
As Overgrown Tomb enters, you may pay 2 life. If you don't, it enters tapped.

Sylvan Library

At the beginning of your draw step, you may draw two additional cards. If you do, choose two cards in your hand drawn this turn. For each of those cards, pay 4 life or put the card on top of your library.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Night's Whisper

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Phyrexian Processor

As Phyrexian Processor enters, pay any amount of life.
{4}, {T}: Create an X/X black Phyrexian Minion creature token, where X is the life paid as Phyrexian Processor entered.

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Snow-Covered Plains

City of Brass

Whenever City of Brass becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.

Kessig Wolf Run

{T}: Add {C}.
{X}{R}{G}, {T}: Target creature gets +X/+0 and gains trample until end of turn.

Sol Ring

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Plateau

Bruse Tarl, Boorish Herder

Whenever Bruse Tarl, Boorish Herder enters or attacks, target creature you control gains double strike and lifelink until end of turn.
Partner (You can have two commanders if both have partner.)

Mana Confluence

{T}, Pay 1 life: Add one mana of any color.

Emiel the Blessed

{3}: Exile another target creature you control, then return it to the battlefield under its owner's control.
Whenever another creature you control enters, you may pay {G/W}. If you do, put a +1/+1 counter on it. If it's a Unicorn, put two +1/+1 counters on it instead. ({G/W} can be paid with either {G} or {W}.)

Mirari's Wake

Creatures you control get +1/+1.
Whenever you tap a land for mana, add one mana of any type that land produced.

Luxury Suite

Luxury Suite enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Undergrowth Stadium

Undergrowth Stadium enters tapped unless you have two or more opponents.
{T}: Add {B} or {G}.

Command Tower

Blood Crypt

({T}: Add {B} or {R}.)
As Blood Crypt enters, you may pay 2 life. If you don't, it enters tapped.

Fire Covenant

As an additional cost to cast this spell, pay X life.
Fire Covenant deals X damage divided as you choose among any number of target creatures.

Cultivator Colossus

Trample
Cultivator Colossus's power and toughness are each equal to the number of lands you control.
When Cultivator Colossus enters, you may put a land card from your hand onto the battlefield tapped. If you do, draw a card and repeat this process.

Badlands

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Kodama's Reach

Moltensteel Dragon

({R/P} can be paid with either {R} or 2 life.)
Flying
{R/P}: Moltensteel Dragon gets +1/+0 until end of turn.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Phyrexian Purge

This spell costs 3 life more to cast for each target.
Destroy any number of target creatures.

Savai Triome

({T}: Add {R}, {W}, or {B}.)
Savai Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Abundance

If you would draw a card, you may instead choose land or nonland and reveal cards from the top of your library until you reveal a card of the chosen kind. Put that card into your hand and put all other cards revealed this way on the bottom of your library in any order.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.