Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Bastion of Remembrance

When Bastion of Remembrance enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Binding the Old Gods

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Destroy target nonland permanent an opponent controls.
II — Search your library for a Forest card, put it onto the battlefield tapped, then shuffle.
III — Creatures you control gain deathtouch until end of turn.

Spitting Dilophosaurus

Whenever Spitting Dilophosaurus enters or attacks, put a -1/-1 counter on up to one target creature.
Creatures your opponents control with -1/-1 counters on them can't block.

Throne of the God-Pharaoh

At the beginning of your end step, each opponent loses life equal to the number of tapped creatures you control.

Tamiyo's Safekeeping

Target permanent you control gains hexproof and indestructible until end of turn. You gain 2 life. (A permanent with hexproof and indestructible can't be the target of spells or abilities your opponents control. Damage and effects that say "destroy" don't destroy it.)

Vraska, Golgari Queen

+2: You may sacrifice another permanent. If you do, you gain 1 life and draw a card.
−3: Destroy target nonland permanent with mana value 3 or less.
−9: You get an emblem with "Whenever a creature you control deals combat damage to a player, that player loses the game."

Necroskitter

Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever a creature an opponent controls with a -1/-1 counter on it dies, you may return that card to the battlefield under your control.

Dusk Urchins

Whenever Dusk Urchins attacks or blocks, put a -1/-1 counter on it.
When Dusk Urchins dies, draw a card for each -1/-1 counter on it.

Llanowar Wastes

{T}: Add {C}.
{T}: Add {B} or {G}. Llanowar Wastes deals 1 damage to you.

Underground Mortuary

({T}: Add {B} or {G}.)
Underground Mortuary enters tapped.
When Underground Mortuary enters, surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Serrated Arrows

Serrated Arrows enters with three arrowhead counters on it.
At the beginning of your upkeep, if there are no arrowhead counters on Serrated Arrows, sacrifice it.
{T}, Remove an arrowhead counter from Serrated Arrows: Put a -1/-1 counter on target creature.

Hapatra, Vizier of Poisons

Whenever Hapatra, Vizier of Poisons deals combat damage to a player, you may put a -1/-1 counter on target creature.
Whenever you put one or more -1/-1 counters on a creature, create a 1/1 green Snake creature token with deathtouch.

Access Tunnel

{T}: Add {C}.
{3}, {T}: Target creature with power 3 or less can't be blocked this turn.

Black Sun's Zenith

Put X -1/-1 counters on each creature. Shuffle Black Sun's Zenith into its owner's library.

Jungle Hollow

Jungle Hollow enters tapped.
When Jungle Hollow enters, you gain 1 life.
{T}: Add {B} or {G}.

Ammit Eternal

Afflict 3 (Whenever this creature becomes blocked, defending player loses 3 life.)
Whenever an opponent casts a spell, put a -1/-1 counter on Ammit Eternal.
Whenever Ammit Eternal deals combat damage to a player, remove all -1/-1 counters from it.

Flourishing Defenses

Whenever a -1/-1 counter is put on a creature, you may create a 1/1 green Elf Warrior creature token.

Karn's Bastion

{T}: Add {C}.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Midnight Banshee

Wither (This deals damage to creatures in the form of -1/-1 counters.)
At the beginning of your upkeep, put a -1/-1 counter on each nonblack creature.

Channeler Initiate

When Channeler Initiate enters, put three -1/-1 counters on target creature you control.
{T}, Remove a -1/-1 counter from Channeler Initiate: Add one mana of any color.

Soul Snuffers

When Soul Snuffers enters, put a -1/-1 counter on each creature.

Skithiryx, the Blight Dragon

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx, the Blight Dragon gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

Skullclamp

Equipped creature gets +1/-1.
Whenever equipped creature dies, draw two cards.
Equip {1}

Cryptolith Rite

Creatures you control have "{T}: Add one mana of any color."

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Twilight Mire

{T}: Add {C}.
{B/G}, {T}: Add {B}{B}, {B}{G}, or {G}{G}.

Triumph of the Hordes

Until end of turn, creatures you control get +1/+1 and gain trample and infect. (Creatures with infect deal damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Temple of Malady

Temple of Malady enters tapped.
When Temple of Malady enters, scry 1.
{T}: Add {B} or {G}.

Nest of Scarabs

Whenever you put one or more -1/-1 counters on a creature, create that many 1/1 black Insect creature tokens.

Slate of Ancestry

{4}, {T}, Discard your hand: Draw a card for each creature you control.

Blooming Marsh

Blooming Marsh enters tapped unless you control two or fewer other lands.
{T}: Add {B} or {G}.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Blossoming Defense

Target creature you control gets +2/+2 and gains hexproof until end of turn.

Thieves' Tools

When Thieves' Tools enters, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
Equipped creature can't be blocked as long as its power is 3 or less.
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

End-Raze Forerunners

Vigilance, trample, haste
When End-Raze Forerunners enters, other creatures you control get +2/+2 and gain vigilance and trample until end of turn.

Wickerbough Elder

Wickerbough Elder enters with a -1/-1 counter on it.
{G}, Remove a -1/-1 counter from Wickerbough Elder: Destroy target artifact or enchantment.

Grasping Dunes

{T}: Add {C}.
{1}, {T}, Sacrifice Grasping Dunes: Put a -1/-1 counter on target creature. Activate only as a sorcery.

Second Harvest

For each token you control, create a token that's a copy of that permanent.

Fume Spitter

Sacrifice Fume Spitter: Put a -1/-1 counter on target creature.

Skinrender

When Skinrender enters, put three -1/-1 counters on target creature.

Liliana's Influence

Put a -1/-1 counter on each creature you don't control. You may search your library and/or graveyard for a card named Liliana, Death Wielder, reveal it, and put it into your hand. If you search your library this way, shuffle.

Undergrowth Stadium

Undergrowth Stadium enters tapped unless you have two or more opponents.
{T}: Add {B} or {G}.

Quillspike

{B/G}, Remove a -1/-1 counter from a creature you control: Quillspike gets +3/+3 until end of turn.

Sol Ring

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Beast Within

Destroy target permanent. Its controller creates a 3/3 green Beast creature token.

Vraska, Swarm's Eminence

Whenever a creature you control with deathtouch deals damage to a player or planeswalker, put a +1/+1 counter on that creature.
−2: Create a 1/1 black Assassin creature token with deathtouch and "Whenever this creature deals damage to a planeswalker, destroy that planeswalker."

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap Staff of Compleation.

Hooded Blightfang

Deathtouch
Whenever a creature you control with deathtouch attacks, each opponent loses 1 life and you gain 1 life.
Whenever a creature you control with deathtouch deals damage to a planeswalker, destroy that planeswalker.

Overgrown Tomb

({T}: Add {B} or {G}.)
As Overgrown Tomb enters, you may pay 2 life. If you don't, it enters tapped.

Woodland Cemetery

Woodland Cemetery enters tapped unless you control a Swamp or a Forest.
{T}: Add {B} or {G}.

Parallel Lives

If an effect would create one or more tokens under your control, it creates twice that many of those tokens instead.

Itlimoc, Cradle of the Sun

(Transforms from Growing Rites of Itlimoc.)
{T}: Add {G}.
{T}: Add {G} for each creature you control.

Growing Rites of Itlimoc

When Growing Rites of Itlimoc enters, look at the top four cards of your library. You may reveal a creature card from among them and put it into your hand. Put the rest on the bottom of your library in any order.
At the beginning of your end step, if you control four or more creatures, transform Growing Rites of Itlimoc.

Growing Rites of Itlimoc // Itlimoc, Cradle of the Sun

Incremental Blight

Put a -1/-1 counter on target creature, two -1/-1 counters on another target creature, and three -1/-1 counters on a third target creature.

Shamanic Revelation

Draw a card for each creature you control.
Ferocious — You gain 4 life for each creature you control with power 4 or greater.

Blowfly Infestation

Whenever a creature dies, if it had a -1/-1 counter on it, put a -1/-1 counter on target creature.

Massacre Girl

Menace
When Massacre Girl enters, each other creature gets -1/-1 until end of turn. Whenever a creature dies this turn, each creature other than Massacre Girl gets -1/-1 until end of turn.

Forest

Beastmaster Ascension

Whenever a creature you control attacks, you may put a quest counter on Beastmaster Ascension.
As long as Beastmaster Ascension has seven or more quest counters on it, creatures you control get +5/+5.

Cauldron of Souls

{T}: Choose any number of target creatures. Each of those creatures gains persist until end of turn. (When it dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Seshiro the Anointed

Other Snake creatures you control get +2/+2.
Whenever a Snake you control deals combat damage to a player, you may draw a card.

Vorinclex, Monstrous Raider

Trample, haste
If you would put one or more counters on a permanent or player, put twice that many of each of those kinds of counters on that permanent or player instead.
If an opponent would put one or more counters on a permanent or player, they put half that many of each of those kinds of counters on that permanent or player instead, rounded down.

Obelisk Spider

Reach
Whenever Obelisk Spider deals combat damage to a creature, put a -1/-1 counter on that creature.
Whenever you put one or more -1/-1 counters on a creature, each opponent loses 1 life and you gain 1 life.

Golgari Signet

Golgari Rot Farm

Golgari Rot Farm enters tapped.
When Golgari Rot Farm enters, return a land you control to its owner's hand.
{T}: Add {B}{G}.

Generous Patron

When Generous Patron enters, support 2. (Put a +1/+1 counter on each of up to two other target creatures.)
Whenever you put one or more counters on a creature you don't control, draw a card.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Devoted Druid

{T}: Add {G}.
Put a -1/-1 counter on Devoted Druid: Untap Devoted Druid.

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Tear Asunder

Kicker {1}{B} (You may pay an additional {1}{B} as you cast this spell.)
Exile target artifact or enchantment. If this spell was kicked, exile target nonland permanent instead.

Swamp

Massacre Girl, Known Killer

Menace
Creatures you control have wither. (They deal damage to creatures in the form of -1/-1 counters.)
Whenever a creature an opponent controls dies, if its toughness was less than 1, draw a card.

Serrated Biskelion

{T}: Put a -1/-1 counter on Serrated Biskelion and a -1/-1 counter on target creature.

Sylvan Anthem

Green creatures you control get +1/+1.
Whenever a green creature you control enters, scry 1.

Plumb the Forbidden

As an additional cost to cast this spell, you may sacrifice one or more creatures. When you do, copy this spell for each creature sacrificed this way.
You draw a card and you lose 1 life.

Toski, Bearer of Secrets

This spell can't be countered.
Indestructible
Toski, Bearer of Secrets attacks each combat if able.
Whenever a creature you control deals combat damage to a player, draw a card.

Assassin's Trophy

Destroy target permanent an opponent controls. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Hapatra's Mark

Target creature you control gains hexproof until end of turn. Remove all -1/-1 counters from it. (A creature with hexproof can't be the target of spells or abilities your opponents control.)

Whispersilk Cloak

Equipped creature can't be blocked and has shroud. (It can't be the target of spells or abilities.)
Equip {2}

Crumbling Ashes

At the beginning of your upkeep, destroy target creature with a -1/-1 counter on it.

Carnifex Demon

Flying
Carnifex Demon enters with two -1/-1 counters on it.
{B}, Remove a -1/-1 counter from Carnifex Demon: Put a -1/-1 counter on each other creature.

Fynn, the Fangbearer

Deathtouch
Whenever a creature you control with deathtouch deals combat damage to a player, that player gets two poison counters. (A player with ten or more poison counters loses the game.)

Opal Palace

{T}: Add {C}.
{1}, {T}: Add one mana of any color in your commander's color identity. If you spend this mana to cast your commander, it enters with a number of additional +1/+1 counters on it equal to the number of times it's been cast from the command zone this game.

Lead

Aftermath (Cast this spell only from your graveyard. Then exile it.)
All creatures able to block target creature this turn do so.

Destined

Target creature gets +1/+0 and gains indestructible until end of turn.

Destined // Lead

Craterhoof Behemoth

Haste
When Craterhoof Behemoth enters, creatures you control gain trample and get +X/+X until end of turn, where X is the number of creatures you control.

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Liliana, Death Wielder

+2: Put a -1/-1 counter on up to one target creature.
−3: Destroy target creature with a -1/-1 counter on it.
−10: Return all creature cards from your graveyard to the battlefield.

Eldrazi Monument

Creatures you control get +1/+1 and have flying and indestructible.
At the beginning of your upkeep, sacrifice a creature. If you can't, sacrifice Eldrazi Monument.

Grim Backwoods

{T}: Add {C}.
{2}{B}{G}, {T}, Sacrifice a creature: Draw a card.

Grim Poppet

Grim Poppet enters with three -1/-1 counters on it.
Remove a -1/-1 counter from Grim Poppet: Put a -1/-1 counter on another target creature.

Ifnir Deadlands

{T}: Add {C}.
{T}, Pay 1 life: Add {B}.
{2}{B}{B}, {T}, Sacrifice a Desert: Put two -1/-1 counters on target creature an opponent controls. Activate only as a sorcery.