Negate

Flesh Reaver

Whenever Flesh Reaver deals damage to a creature or opponent, Flesh Reaver deals that much damage to you.

Morphic Pool

Morphic Pool enters the battlefield tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Phyrexian Obliterator

Trample
Whenever a source deals damage to Phyrexian Obliterator, that source's controller sacrifices that many permanents.

Asmodeus the Archfiend

Binding Contract — If you would draw a card, exile the top card of your library face down instead.
{B}{B}{B}: Draw seven cards.
{B}: Return all cards exiled with Asmodeus the Archfiend to their owner's hand and you lose that much life.

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Djinn of Infinite Deceits

Flying
{T}: Exchange control of two target nonlegendary creatures. You can't activate this ability during combat.

Island

Desecration Elemental

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
Whenever a player casts a spell, sacrifice a creature.

Homeward Path

{T}: Add {C}.
{T}: Each player gains control of all creatures they own.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Castle Locthwain

Castle Locthwain enters the battlefield tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Phyrexian Negator

Trample
Whenever Phyrexian Negator is dealt damage, sacrifice that many permanents.

Archfiend of the Dross

Flying
Archfiend of the Dross enters the battlefield with four oil counters on it.
At the beginning of your upkeep, remove an oil counter from Archfiend of the Dross. Then if it has no oil counters on it, you lose the game.
Whenever a creature an opponent controls dies, its controller loses 2 life.

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Countersquall

Counter target noncreature spell. Its controller loses 2 life.

Steel Golem

Heartless Summoning

Creature spells you cast cost {2} less to cast.
Creatures you control get -1/-1.

Evil Eye of Orms-by-Gore

Non-Eye creatures you control can't attack.
Evil Eye of Orms-by-Gore can't be blocked except by Walls.

Hellcarver Demon

Flying
Whenever Hellcarver Demon deals combat damage to a player, sacrifice all other permanents you control and discard your hand. Exile the top six cards of your library. You may cast any number of spells from among cards exiled this way without paying their mana costs.

Taniwha

Trample
Phasing (This phases in or out before you untap during each of your untap steps. While it's phased out, it's treated as though it doesn't exist.)
At the beginning of your upkeep, all lands you control phase out. (They phase in before you untap during your next untap step.)

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature.

Polluted Delta

{T}, Pay 1 life, Sacrifice Polluted Delta: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Infernal Grasp

Destroy target creature. You lose 2 life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Greater Harvester

At the beginning of your upkeep, sacrifice a permanent.
Whenever Greater Harvester deals combat damage to a player, that player sacrifices two permanents.

Maze of Ith

{T}: Untap target attacking creature. Prevent all combat damage that would be dealt to and dealt by that creature this turn.

Plague Reaver

At the beginning of your end step, sacrifice each other creature you control.
Discard two cards, Sacrifice Plague Reaver: Choose target opponent. Return Plague Reaver to the battlefield under that player's control at the beginning of their next upkeep.

Crawlspace

No more than two creatures can attack you each combat.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters the battlefield tapped unless you control two or more basic lands.

Mana Crypt

At the beginning of your upkeep, flip a coin. If you lose the flip, Mana Crypt deals 3 damage to you.
{T}: Add {C}{C}.

Thought Devourer

Flying
Your maximum hand size is reduced by four.

Arcane Denial

Counter target spell. Its controller may draw up to two cards at the beginning of the next turn's upkeep.
You draw a card at the beginning of the next turn's upkeep.

Grid Monitor

Slip Out the Back

Put a +1/+1 counter on target creature. It phases out. (Treat it and anything attached to it as though they don't exist until its controller's next turn.)

Neurok Stealthsuit

Equipped creature has shroud. (It can't be the target of spells or abilities.)
{U}{U}: Attach Neurok Stealthsuit to target creature you control.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Demonic Taskmaster

Flying
At the beginning of your upkeep, sacrifice a creature other than Demonic Taskmaster.

Arcane Signet

Aetherize

Return all attacking creatures to their owner's hand.

Liege of the Pit

Flying, trample
At the beginning of your upkeep, sacrifice a creature other than Liege of the Pit. If you can't, Liege of the Pit deals 7 damage to you.
Morph {B}{B}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Counterspell

No Mercy

Whenever a creature deals damage to you, destroy it.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Abyssal Persecutor

Flying, trample
You can't win the game and your opponents can't lose the game.

Evil Eye of Urborg

Non-Eye creatures you control can't attack.
Whenever Evil Eye of Urborg becomes blocked by a creature, destroy that creature.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Drinker of Sorrow

Drinker of Sorrow can't block.
Whenever Drinker of Sorrow deals combat damage, sacrifice a permanent.

Switcheroo

Exchange control of two target creatures.

Cursed Totem

Activated abilities of creatures can't be activated.

Ebonblade Reaper

Whenever Ebonblade Reaper attacks, you lose half your life, rounded up.
Whenever Ebonblade Reaper deals combat damage to a player, that player loses half their life, rounded up.
Morph {3}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Despotic Scepter

{T}: Destroy target permanent you own. It can't be regenerated.

Painwracker Oni

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
At the beginning of your upkeep, sacrifice a creature if you don't control an Ogre.

Grinning Demon

At the beginning of your upkeep, you lose 2 life.
Morph {2}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Choked Estuary

As Choked Estuary enters the battlefield, you may reveal an Island or Swamp card from your hand. If you don't, Choked Estuary enters the battlefield tapped.
{T}: Add {U} or {B}.

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this artifact: Add one mana of any color.")

Wrong Turn

Target opponent gains control of target creature. (If an attacking or blocking creature changes controllers, it's removed from combat.)

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Yukora, the Prisoner

When Yukora, the Prisoner leaves the battlefield, sacrifice all non-Ogre creatures you control.

Rust Elemental

Flying
At the beginning of your upkeep, sacrifice an artifact other than Rust Elemental. If you can't, tap Rust Elemental and you lose 4 life.

Damnation

Destroy all creatures. They can't be regenerated.

Command Beacon

{T}: Add {C}.
{T}, Sacrifice Command Beacon: Put your commander into your hand from the command zone.

Rotting Regisaur

At the beginning of your upkeep, discard a card.

Desecration Demon

Flying
At the beginning of each combat, any opponent may sacrifice a creature. If a player does, tap Desecration Demon and put a +1/+1 counter on it.

Fateful Handoff

Draw cards equal to the mana value of target artifact or creature you control. An opponent gains control of that permanent.

Ancient Tomb

{T}: Add {C}{C}. Ancient Tomb deals 2 damage to you.

Jon Irenicus, Shattered One

At the beginning of your end step, target opponent gains control of up to one target creature you control. Put two +1/+1 counters on it and tap it. It's goaded for the rest of the game and it gains "This creature can't be sacrificed." (It attacks each combat if able and attacks a player other than you if able.)
Whenever a creature you own but don't control attacks, you draw a card.

Reality Shift

Exile target creature. Its controller manifests the top card of their library. (That player puts the top card of their library onto the battlefield face down as a 2/2 creature. If it's a creature card, it can be turned face up any time for its mana cost.)

Thought Eater

Flying
Your maximum hand size is reduced by three.

Lord of the Pit

Flying, trample
At the beginning of your upkeep, sacrifice a creature other than Lord of the Pit. If you can't, Lord of the Pit deals 7 damage to you.

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap Staff of Compleation.

Drowned Catacomb

Drowned Catacomb enters the battlefield tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Castle Vantress

Castle Vantress enters the battlefield tapped unless you control an Island.
{T}: Add {U}.
{2}{U}{U}, {T}: Scry 2.

Phage the Untouchable

When Phage the Untouchable enters the battlefield, if you didn't cast it from your hand, you lose the game.
Whenever Phage deals combat damage to a creature, destroy that creature. It can't be regenerated.
Whenever Phage deals combat damage to a player, that player loses the game.

Phyrexian Vatmother

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
At the beginning of your upkeep, you get a poison counter.